Prevention of coronary heart disease in clinical practice. Summary of recommendations of the Second Joint Task Force of European and other Societies* on Coronary Prevention

Wood, David; Backer, Guy De; Færgeman, Ole; Graham, Ian; Mancia, Giuseppe; Pyörälà, Kalevi

doi:10.1097/00004872-199816100-00003

Cited by 474 publications

(663 citation statements)

References 2 publications

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“…The baseline mean cholesterol value for our group of patients was much lower (3.52 ± 0.846 mmol/L; n = 100). This was partly caused by the inclusion criteria which did not allow the inclusion of anyone with total cholesterol Ͼ7 mmol/L and LDL Ͼ6 mmol/L, because these hypertensive patients should be, according to current guidelines, 24 treated with lipid-lowering drugs. Over a period of 12 years, there has also been a statistically significant decline in the mean total cholesterol value in a middle-aged random population sample in the Czech Republic.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the effects of fixed combinations of sustained-release verapamil/trandolapril versus captopril/hydrochlorothiazide on metabolic and electrolyte parameters in patients with essential hypertension

Cífková

Nakov²,

Novozámská

et al. 2000

J Hum Hypertens

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The objective of this randomised open, active controlled, cross-over study was to evaluate the effect of a fixed combination of verapamil SR/trandolapril compared to captopril/hydrochlorothiazide on serum lipids, lipoproteins, and other metabolic and electrolyte parameters in patients with essential hypertension. Another objective was to assess the efficacy and safety of both combinations. One hundred hypertensives with systolic blood pressure 140-209 mm Hg and diastolic blood pressure 90-119 mm Hg were evaluated after 16 weeks receiving a fixed combination of verapamil SR 180 mg/ trandolapril 2 mg (VT) or captopril 50 mg/hydrochlorothiazide 25 mg (CH) both given once daily. Lipids and lipoproteins were assessed in duplicate on 2 consecutive days. The study was completed by 80 patients. There was no statistically significant difference between the two combined regimens with respect to low-density lipoprotein (LDL)-cholesterol for the 'intention-to-treat'

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Section: Discussionmentioning

confidence: 99%

Evaluation of the effects of fixed combinations of sustained-release verapamil/trandolapril versus captopril/hydrochlorothiazide on metabolic and electrolyte parameters in patients with essential hypertension

Cífková

Nakov²,

Novozámská

et al. 2000

J Hum Hypertens

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“…It has been also reported that low HDL-C levels represent one of the most prevalent lipid abnormality in the subjects affected by CHD [3,4], and unlike high total cholesterol (TC) levels, low HDL-C levels seem to maintain a significant predictive value for CHD in the older population [5]. Therefore, several recent guidelines [6][7][8] consider low HDL-C levels a strong and independent risk factor for CHD.…”

Section: Introductionmentioning

confidence: 99%

High interleukin-6 plasma levels are associated with low HDL-C levels in community-dwelling older adults: The InChianti study

et al. 2007

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“…As secondary prevention for patients with coronary heart disease, diet is an integral part of the overall management (Wood et al, 1998). A population-based primary prevention strategy relies on non-pharmacological interventions.…”

Section: Introductionmentioning

confidence: 99%

“…A population-based primary prevention strategy relies on non-pharmacological interventions. Diet is fundamental in this respect, and national as well as international dietary guidelines have been issued with recommendations to reduce dietary intake of saturated fat and to increase intake of dietary ®bre (Sandstro Èm et al, 1996;Swedish National Food Administration, 1997;Wood et al, 1998). Cholesterol can only be eliminated from the body by faecal excretion, except minor amounts of metabolites of steroid hormones in urine.…”

Section: Introductionmentioning

confidence: 99%

Will recommended changes in fat and fibre intake affect cholesterol absorption and sterol excretion? An ileostomy study

2000

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Objective: To study cholesterol absorption and excretion in ileostomy subjects with different intakes of saturated fat and dietary ®bre. Design: Short-term experimental study, with four controlled diets in repeated measurements. Setting: Out-patients at metabolic-ward kitchen. Subjects: Nine healthy volunteers with conventional ileostomy after colectomy because of ulcerative colitis. Interventions: Four diet periods, each of 3 days duration: high saturated fat and low dietary ®bre (STAND); reduced saturated fat (RESAT); high saturated fat and high ®bre (FATFIB); and reduced saturated fat and high ®bre (RESATFIB). Main outcome measures: Absorption of cholesterol, and ileal excretion of cholesterol, bile acids, fat and energy. Differences between diets evaluated with Friedman's two-way analysis of variance by rank sum with Bonferroni adjustment, and post hoc differences assessed by rank sum comparison. Results: RESAT and RESATFIB reduced fractional cholesterol absorption by 7% and 10%; RESATFIB and FATFIB increased net cholesterol excretion by 46% and 54% respectively. Further, RESATFIB increased net sterol excretion by 18%, all compared to STAND (P`0.05 for all). All three intervention diets contained more phytosterols than STAND (P`0.05), and the phytosterol content was inversely correlated to fractional cholesterol absorption (r 7 0.77, P`0.01). Conclusions: Current nutrition recommendations to reduce saturated fat and increase dietary ®bre affect sterol excretion additively. The effect on cholesterol absorption might be partly explained by the content of dietary plant sterols. Sponsorship: Supported by grants from the Gothenburg Medical Society, grant numbers 94a086 and 99a082, and by the University of Gothenburg.

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Prevention of coronary heart disease in clinical practice. Summary of recommendations of the Second Joint Task Force of European and other Societies* on Coronary Prevention

Cited by 474 publications

References 2 publications

Evaluation of the effects of fixed combinations of sustained-release verapamil/trandolapril versus captopril/hydrochlorothiazide on metabolic and electrolyte parameters in patients with essential hypertension

Evaluation of the effects of fixed combinations of sustained-release verapamil/trandolapril versus captopril/hydrochlorothiazide on metabolic and electrolyte parameters in patients with essential hypertension

High interleukin-6 plasma levels are associated with low HDL-C levels in community-dwelling older adults: The InChianti study

Will recommended changes in fat and fibre intake affect cholesterol absorption and sterol excretion? An ileostomy study

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