Prevention of complications of iatrogenic transient bacteremia in dental practice

Abstract

The aim of the work was to develop an algorithm of anti-microbial chemotherapy for the perioperative prevention of local inflammatory complications. To clarify the data on possible pathogens of postoperative local inflammatory complications, the authors conducted their own microbiological studies to determine the microbiome of an operating wound under the conditions of aerobic and anaerobic cultivation of inoculum with subsequent identification by a complex of morphological, cultural and biochemical properties. Periodontal pathogens were identified by PCR. The microbiome of the surgical wound was analyzed for conditionally clean wounds (group 1 — 61 patients after dental implantation surgery), infected (group 2-41 patients with a diagnosis of pericoronitis, difficult eruption of the wisdom tooth) and contaminated (group 3 — 42 patients after cystectomy, granulomectomy). Based on the literature data and the results of our own research, an algorithm of antimicrobial chemotherapy (prevention) for outpatient operations in dental practice has been developed. The algorithm includes the most commonly used drugs by dentists, taking into account the microbiota of the postoperative wound, the sensitivity of pathogens to antibiotics, and the duration of treatment courses.