2006
DOI: 10.1002/ccd.20812
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Prevention of arterial spasm during percutaneous coronary interventions through radial artery: The SPASM study

Abstract: Radial artery spasm during transradial percutaneous interventions was effectively prevented by the administration of vasodilators. The combination of verapamil 2.5 mg and molsidomine 1 mg provided the strongest relative risk reduction of spasm compared to placebo and should therefore be recommended during percutaneous coronary interventions through the radial approach.

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Cited by 113 publications
(68 citation statements)
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“…Apesar de se tratar de um registro, os resultados foram corroborados pela ausência de diferenças entre os grupos nas principais características basais (idade, porcentagem de mulheres, peso e altura), sendo pacientes mais jovens, sexo feminino, diabetes melito e baixo peso corporal considerados preditores de espasmo da artéria radial em vários estudos. [12][13][14] Semelhante à técnica femoral, a abordagem radial necessita de um período de aprendizado provavelmente mais longo. 15,16 O material utilizado nesse acesso teve melhora gradual em relação à redução do tamanho dos cateteres, desenho de novas curvas adaptadas à técnica radial e prevenção de espasmo.…”
Section: Discussionunclassified
“…Apesar de se tratar de um registro, os resultados foram corroborados pela ausência de diferenças entre os grupos nas principais características basais (idade, porcentagem de mulheres, peso e altura), sendo pacientes mais jovens, sexo feminino, diabetes melito e baixo peso corporal considerados preditores de espasmo da artéria radial em vários estudos. [12][13][14] Semelhante à técnica femoral, a abordagem radial necessita de um período de aprendizado provavelmente mais longo. 15,16 O material utilizado nesse acesso teve melhora gradual em relação à redução do tamanho dos cateteres, desenho de novas curvas adaptadas à técnica radial e prevenção de espasmo.…”
Section: Discussionunclassified
“…Several RAS-associated factors have been identified including patient-related factors (female gender, young age, low body mass index, short stature, small radial artery diameter, diabetes mellitus, dyslipidaemia, anxiety, anomalous radial artery) and technical factors (low radial-artery-to-sheath ratio, non-hydrophilic coated sheaths, unsuccessful access at first attempt, prolonged cannulation, multiple catheter exchanges, excessive catheter manipulations, limited operator experience) [8,[15][16][17][18][19][20][21]. In the present study, radial artery pulse grading, which was found to be correlated with radial artery diameter, female sex, and larger catheter size were demonstrated as predictors of RAS.…”
Section: Discussionmentioning
confidence: 99%
“…Many preventive measures have been suggested to prevent spasm of the radial artery such as sedation, adequate analgesia, hydrophilic coated sheaths, and intra-arterial vasodilators [7,8,17]. Various drugs have been extensively evaluated to prevent spasm of radial artery, but there is currently no agreement on the optimal agents.…”
Section: Discussionmentioning
confidence: 99%
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“…In addition to premedication and local anaesthesia, intraarterial administration of vasodilatators is essential. Various spasmolytic cocktails have been tried [5]. Verapamil is the most commonly used vasodilatator, being administered directly after sheath insertion in a dose of 2.5 up to 5.0 mg (diluted up to 10 ml with saline).…”
Section: Sheath Sizementioning
confidence: 99%