Prevalência e características clínicas da sibilância em crianças no primeiro ano de vida, residentes na cidade de Cuiabá, Mato Grosso, Brasil1

Abstract

OBJECTIVE: To evaluate the prevalence and the clinical characteristics of wheezing in infants aged 12 to 15 months in the city of Cuiabá, Mato Grosso State, Midwest Brazil. METHODS: Parents and/or guardians of infants were interviewed and completed a written standardized questionnaire of the Estudio Internacional de Sibilancia en Lactantes (EISL) - phase 3 at primary healthcare clinics at the same day of children vaccination or at home, from August of 2009 to November of 2010. RESULTS: 1,060 parents and/or guardians completed the questionnaire, and 514 (48.5%) infants were male. Among the studied infants, 294 (27.7%) had at least one episode of wheezing during the first year of life, beggining at 5.8±3.0 months of age, with a predominance of male patients. The prevalence of occasional wheezing (<3 episodes of wheezing) was 15.0% and recurrent wheezing (≥3 episodes) was 12.7%. Among the infants with recurrent wheezing, the use of inhaled β2-agonist, oral corticosteroid, leukotriene receptor antagonist, as well as night symptoms, respiratory distress, and hospitalization due to severe episodes were significantly more frequent. Physician-diagnosed asthma was observed in 28 (9.5%) of the wheezing infants. Among the wheezing infants, 80 (27.7%) were diagnosed with pneumonia, of whom 33 (11.2%) required hospitalization; neverthless, no differences between occasional and recurrent wheezing infants were found. CONCLUSIONS: The prevalence of recurrent wheezing and physician-diagnosed asthma in infants were lower compared with those observed in other Brazilian studies. Recurrent wheezing had early onset and high morbity.

Factors affecting exclusive breastfeeding in the first month of life among Amazonian children

“…Wheezing infants’ prevalence varies among settings, being more frequent in Latin American than in European countries [62]. This difference implies the influence of local environmental factors on the clinical expression of several wheezing phenotypes in childhood [63]. Thus, the prevalence of factors, such as maternal asthma, smoking, antibiotic use and caesarean sections, may influence the willingness and capacity of mothers to breastfeed [64].…”

Associação entre sibilância e antropometria: um estudo com lactentes beneficiários do programa Bolsa Família

“…O sintoma de sibilância nos últimos seis meses, no presente estudo, foi identificado em metade dos (as) lactentes, percentuais divergentes dos resultados encontrados na literatura, assim como a metodologia de diagnóstico da sibilância. Para , 54% foi o percentual de crises da sibilância nos últimos meses entre as crianças, enquanto Solé et al (2008), a prevalência de 80,3% de lactentes com sibilância no primeiro ano e vida e em Moraes et al (2014), prevalência 27,7% em lactentes, que procuraram as Unidades Básicas de Saúde, por ocasião da vacinação de rotina ou durante visitas nos domicílios de crianças matriculadas nos programas de saúde da família.…”

Impactos Clínicos E Sociais Causados Pela Pandemia

“…Nessa faixa etária, esses receptores podem apresentar diferenças na sua configuração, concentração e na capacidade de ligação com o vírus (SAFADI, 2020), (MARTINS et al, 2021).…”

“…Especula-se que as crianças frequentemente manifestam infecções respiratórias tendo assim níveis mais altos de anticorpos contra o vírus, o que limita a replicação do SARS-CoV-2 por competição direta de virus-to-virus (SAFADI, 2020), (MARTINS et al, 2021). Outra hipótese atribuída ao melhor prognóstico em crianças deve-se ao sistema imune inato ser mais desenvolvido e efetivo na infância.…”