Prevalência de neoplasias diagnosticadas em cães no Hospital Veterinário da Universidade Eduardo Mondlane, Moçambique

Santos, Ivan Felismino Charas dos; Cardoso, Juliana; Oliveira, Kátia Cilene Cavalcante de; Laisse, Cláudio João Mourão; Bessa, S.

doi:10.1590/s0102-09352013000300025

Cited by 9 publications

(13 citation statements)

References 7 publications

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“…The cutaneous tumors were the most frequent in this article. The high frequency could be explained because cutaneous tumors are more visible and clinically explorable, this agrees with other reports (Santos et al, 2013;Choi et al, 2016;Grüntzig et al, 2016). Into the group of the cutaneous tumor; the tumors associated with exposure to solar radiation were the most frequent.…”

Section: Discusionsupporting

confidence: 91%

“…The highest frequencies of tumors observed in dogs older than 7 years are comparable to those published in Mexico and other countries (Fajardo et al, 2013;Brønden et al, 2010;Santos et al, 2013), which have been associated with more prolonged exposure to risk factors and thus to mutations accumulated in cell cycle regulatory genes and other cell genes (Reif, 2007). Further, the survey showed most people had adult dogs.…”

Section: Discusionsupporting

confidence: 77%

“…The most popular dogs in the retrospective study were pure breeds (82.5%) analogous to reported in other articles (Fajardo et al, 2013;Santos et al, 2013). Nevertheless, in the survey mixed breeds were the most popular breeds, however, there is no information about predisposition of dogs with a lot of genetic variability to a specific tumor; therefore, further research should be done.…”

Section: Discusionsupporting

confidence: 64%

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Epidemiology of tumors in dogs in the capital of the state of Mexico from 2002-2016

García

Alpízar

Fajardo

et al. 2019

Arq. Bras. Med. Vet. Zootec.

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A retrospective and cross-sectional study of canine tumors was performed in the capital of State of Mexico from 2002-2016. Since then, 393 tumors were remitted. Descriptive epidemiology was made from all data: breed, age, sex, and tumor features. Then the risk association between cutaneous and non-cutaneous tumors with variables such as sex, breed, and age were analyzed through an exact Fisher test and Odds ratio. In addition, some characteristics of the canine population were studied under a survey. Of all tumors, skin tumors were the most frequent (59.0%). The group of tumors related to ultraviolet radiation was the most common (15.1%). The frequency of tumors in females was 53%, nevertheless, males had more risk to develop cutaneous tumors (OR=1.88, 1.24-2.84) (0.003). The Pure breeds were the most common (82.5%) and the most frequent age range was > 7 years (54.7%). The survey showed that males (53%) and the age range 1-7 years (62.1%) were the most frequent. Conclusions, age, breed, and sex were identified as the major risk factors for tumorigenesis. Likewise, skin tumors were associated with exposure to ultraviolet radiation, probably to the height of the locality (2667mamls).

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Section: Discusionsupporting

confidence: 91%

Section: Discusionsupporting

confidence: 77%

Section: Discusionsupporting

confidence: 64%

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Epidemiology of tumors in dogs in the capital of the state of Mexico from 2002-2016

García

Alpízar

Fajardo

et al. 2019

Arq. Bras. Med. Vet. Zootec.

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“…Já Meirelles et al (2010), descreveram valores ainda menores, na ordem de 1% deste tumor. Santos et al (2013), encontraram valores de 3% dessa mesma neoplasia. No presente estudo foram encontrados valores superiores, na ordem de 7,07% dessa neoplasia.…”

Section: Resultsunclassified

Comparação entre a citopatologia por biopsia com agulha fina e a histopatologia no diagnóstico das neoplasias cutâneas e subcutâneas de cães

Braz

Brum²,

Leal

et al. 2016

Pesq. Vet. Bras.

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ABSTRACT. - The cutaneous cancers are among the most frequently diagnosed in veterinary medicine before it is sought that the diagnosis of these tumors are fast and effective. In veterinary medicine the use of cytology as a method for diagnosis has increased. Therefore is necessary that studies demonstrate the technical efficiency so that it can be used as only tool. This study aimed to compare the diagnosis made by cytological and histological techniques. Skin and subcutaneous tumors of dogs and their neoplastic type are more easily diagnosed by cytology and are the most prevalent tumors in this animal spécies, attended by two veterinary hospitals in Campo Grande/MS from March 2012 to December 2013. Tumor cell samples were collected by fine needle aspiration and surgical punch of 91 dogs. The cytological results showed an efficacy of 69.69% in relation to histopathology. For differentiating between neoplastic and non-neoplastic growth, the efficiency increases to 91.91%. In order to differentiate benign from malignant tumors, it was possible to find an agreement in the order of 68.13%. The most prevalent tumors were mastocytoma, followed by lipoma, fibrosarcoma and basal cell tumor.

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“…The incidence rates for CMT depends on the geographic origin given that it is a tumor with higher prevalence in countries where castration is not routinely performed [2]. In Brazil, the prevalence of CMT in intact female dogs is approximately 28% to 45% of all tumors in dogs [3,4]. CMTs resemble human breast cancer (BC), and dogs represent an interesting model for comparative studies.…”

Section: Introductionmentioning

confidence: 99%

Deregulation of VEGFR-2 and PGFR Expression and Microvascular Density in a Triple-Negative Model of Canine Malignant Mammary Tumors with Lymph Node or Lung Metastasis

Anjos¹,

Vital²,

Lainetti³

et al. 2018

Preprint

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Canine mammary tumors (CMT) are the most common cancer in noncastrated female dogs. Interestingly, triple-negative tumors are the most common molecular subtype in female dogs. In this study, we proposed to evaluate the expression of VEGFR-2, PDGFR and microvascular density (MVD) in a group of metastatic and nonmetastatic triple-negative CMT and compare the expression based on clinical parameters. Twenty-six female dogs with triple-negative mammary tumors were divided into three groups: nonmetastatic tumors (NMT) (N=11), tumors with lymph node metastasis (LNM) (N=10) and tumors with lung metastasis (LM) (N=5). We observed increased VEGFR-2 expression in LNM compared with NMT and a positive correlation between tumor grade and VEGFR-2 expression. A positive correlation was noted between VEGFR-2 and PDGFR expression. Regarding microvascular density (MVD), we identified a higher number of vessels in primary tumors with lymph node metastasis and lung metastasis compared with tumors with no metastasis. The primary tumors with lung metastasis exhibited an increased MVD compared with carcinoma with lymph node metastasis. Overall, our results suggest a deregulation of VEGFR-2 and PDGFR and high MVD in metastatic tumors, indicating a role for angiogenesis in tumor progression.

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Prevalência de neoplasias diagnosticadas em cães no Hospital Veterinário da Universidade Eduardo Mondlane, Moçambique

Cited by 9 publications

References 7 publications

Epidemiology of tumors in dogs in the capital of the state of Mexico from 2002-2016

Epidemiology of tumors in dogs in the capital of the state of Mexico from 2002-2016

Comparação entre a citopatologia por biopsia com agulha fina e a histopatologia no diagnóstico das neoplasias cutâneas e subcutâneas de cães

Deregulation of VEGFR-2 and PGFR Expression and Microvascular Density in a Triple-Negative Model of Canine Malignant Mammary Tumors with Lymph Node or Lung Metastasis

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