Prevalence, severity and clinical features of psoriasis in fingernails and toenails in adult patients: Italian experience

Brazzelli, Valeria; Carugno, Andrea; Alborghetti, Arianna; Grasso, Vincenzo; Cananzi, Raffaello; Fornara, L.; Silvestri, Annalisa De; Borroni, G.

doi:10.1111/j.1468-3083.2011.04289.x

Cited by 70 publications

(88 citation statements)

References 20 publications

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“…An Italian study published in 2012 found onycholysis to be the most frequent symptom among the 178 patients studied. 11 On the other hand, a study conducted by Salomon and colleagues on a sample of 106 inpatients found nail hyperkeratosis to be the most common manifestation of nail psoriasis. 12 …”

Section: Clinical Manifestationsmentioning

confidence: 98%

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Nail psoriasis: a review of the literature

Schons

Knob

Murussi

et al. 2014

An. Bras. Dermatol.

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Nails are considered epidermal appendages, and as such, are commonly affected in patients with psoriasis, 80% of whom are likely to develop nail psoriasis as a result of their condition. Two patterns of nail disorders have been shown to be caused by psoriasis. Nail matrix involvement can result in features such as leukonychia, pitting (punctures or cupuliform depressions), red spots in the lunula and crumbling. Nail bed involvement, on the other hand, can cause onycholysis, salmon or oil-drop patches, subungual hyperkeratosis and splinter hemorrhages. Nail disease causes aesthetic and functional impairment, and is indicative of more severe forms of psoriasis as well as of joint involvement. The treatment for nail psoriasis involves behavioral interventions, topical medications, or systemic therapy in case of extensive skin or joint involvement. This article presents a review of the main features of nail psoriasis, its clinical presentation, diagnostic and assessment methods, clinical repercussions, and of its available treatment options.

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Section: Clinical Manifestationsmentioning

confidence: 98%

“…5 Among patients with psoriatic arthritis, the prevalence of nail involvement may be as high as 80.5%. 6,7 In 1 to 5% of patients, alterations compatible with nail psoriasis may also occur in the absence of cutaneous lesions. 8 …”

Section: The Epidemiology Of Nail Psoriasismentioning

confidence: 99%

Nail psoriasis: a review of the literature

Schons

Knob

Murussi

et al. 2014

An. Bras. Dermatol.

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“…In a study in 2012 on changes in the skin and nails of patients with renal disease, onycholysis prevalence was reported 13.1 percent (14). In another study on patients with psoriasis, the prevalence of this nail disease has been reported up to78% (15). By comparing these values, we can conclude that onycholysis is not among common nail disorders in severe acne vulgaris and probably there is no connection between these two disorders.…”

Section: Discussionmentioning

confidence: 73%

Determining the Prevalence and Types of Nail Involvement in Patients with Severe Acne Vulgaris Who Referred to Clinic of Dermatology of Rasoul-e-akram Hospital During 2010-2011

Ghasemi

Ghafarpour

E³

et al. 2017

IMMINV

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Background: Various skin diseases such as psoriasis, lichen planus, and alopecia areata can be associated with structural nail lesions. However, nail lesions prevalence in patients with severe acne vulgaris is not determined. This study aimed to determine the frequency and types of nail lesions in patients with severe acne vulgaris. Methods: In this cross-sectional study, 235 patients with severe acne vulgaris were included from the clinic of dermatology of Rasoul-e-akram Hospital during the 2010-2011. The patients had no history of treatment for acne vulgaris. Patients initially underwent clinical examination, and severity of acne was determined among them. Demographic characteristics such as sex, age, and blood type, and nail disorders including brittleness, onycholysis, and leukonychia were investigated in these patients. Data were analyzed using SPSS 18 software. Results: In this study,79 (33.6%) patients with severe acne vulgaris had nail involvement and the frequency of nail lesions in this study were as follow: brittle nails 26.8% (63 cases); leukonychia 18.2% (43 cases); parrot-beaked nails 3.4% (8 cases) and onycholysis 1.3% (3 cases). Nail disorders in patients with severe acne vulgaris were not associated with sex, blood group, and the severity and distribution of acne lesions. However, the lower age of the patients was associated with the incidence of nail disorders.

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“…Se recogió información sobre datos demográficos y clínicos de acuerdo a un protocolo preespecificado. Resultados: Se incluyeron 528 pacientes con psoriasis (edad media: 46,7 años; 60,2% hombres; 39,8% mujeres; 89,8% psoriasis en placas; mediana de PASI 3,2 [1,[5][6][7]4]). Presentaron otra EIMI 82 pacientes (15,5% [IC 95%: 12,(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)9]).…”

Section: Palabras Claveunclassified

Immune-Mediated Inflammatory Diseases and Other Comorbidities in Patients With Psoriasis: Baseline Characteristics of Patients in the AQUILES Study

Vanaclocha

Crespo-Erchiga

Jiménez‐Puya

et al. 2015

Actas Dermo-Sifiliográficas (English Edition)

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Prevalence, severity and clinical features of psoriasis in fingernails and toenails in adult patients: Italian experience

Abstract: Our study confirms that nail involvement may be overlooked in psoriasis patients. Different psoriatic patterns in the nail affect specific digits more frequently.

Cited by 70 publications

References 20 publications

Nail psoriasis: a review of the literature

Nail psoriasis: a review of the literature

Determining the Prevalence and Types of Nail Involvement in Patients with Severe Acne Vulgaris Who Referred to Clinic of Dermatology of Rasoul-e-akram Hospital During 2010-2011

Immune-Mediated Inflammatory Diseases and Other Comorbidities in Patients With Psoriasis: Baseline Characteristics of Patients in the AQUILES Study

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