Background: Body's locomotor system, at any given age, need to be pain-free, agile, stable and energetic, symmetrical in joint functional system and muscle power. Joint Functional Screening (JFS) is a musculo-skeletal profiling program via a systematic clinical examination with clinical reasoning of the entire human joints' functional system, with or without causative limitation to derive a holistic analysis to give a health provider, the strength, flexibility, and stability indicators of the musculoskeletal system. Objective: The purpose of this study was to introduce a feasible and an affordable clinical examination package as Joint Functional Screening. Method: This package including clinical tools to analysis and screen all body joints which can determine muscular imbalances and body abnormalities. Conclusion: JFS is an innovation program to profile a normal musculoskeletal state to decode any underlying anomalies of the body, in an otherwise normal subject, who might be preparing to take up any sporty or gym activities in one's lifespan that could elicit or uproot an injury which could be otherwise prevented.