Prevalence, predictors and perinatal outcomes of peri-conceptional alcohol exposure - retrospective cohort study in an urban obstetric population in Ireland

Mullally, Aoife; Cleary, Brian; Barry, Joe; Fahey, Tom; Murphy, Deirdre J.

doi:10.1186/1471-2393-11-27

Cited by 78 publications

(69 citation statements)

References 16 publications

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“…The rate of drinkers among pregnant women of our series (32.5%) is much higher than that of 4.4% reported in an Indian series [10]) and in North America (10% in USA and 17% -25% in Canada [11]). Rates reported in Europe vary considerably from 34% in France [12] to 81% in Ireland [13]. Due to feeling of guilt or shame likely to accompany self-reporting of alcohol consumption by pregnant women [14], the actual rate of our study might have to be higher.…”

Section: Commentsmentioning

confidence: 44%

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Effect of maternal alcohol consumption on gestational diabetes detection and mother-infant’s outcomes in Kinshasa, DR Congo

Barthélémy¹,

Andy²,

Roger³

2011

OJOG

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Objectives: Since it has been suggested that moderate alcohol drinking would increase insulin sensitivity, which could benefit Gestational Diabetes Mellitus (GDM), the study aimed at evaluating alcohol consumption during pregnancy, and seeing whether this consumption influences GDM detection and maternal/perinatal outcomes. Study design: Women with already known diabetes and those with multiple pregnancy were excluded. All other pregnant women attending antenatal care unit of the university clinics, Kinshasa, DR Congo during the period from 1 March throughout 31 October 2010, were invited at 24-week gestation to enroll in O'Sullivan blood glucose testing and if eligible in 100-gram oral glucose tolerance test. Alcohol consumption, risk factors for GDM, and general characteristics such as age, parity, gestity, BMI, fat mass were registered. Diagnosed GDM was first treated with diet and exercise, thereafter with Metformin, and if necessary with insulin. For other (normal) women data remained blinded until confinement. Maternal and infant's adverse outcomes such as maternal urinary infection, preeclampsia, cesarean section, intrauterine growth retardation, birth weight < 2500 g, birth weight ≥ 3800 g (as stated > percentile 90 in our milieu), Apgar score at the first minute < 7, shoulder dystocia or other birth injury, neonatal hypoglycemia and fetal alcohol syndrome (FAS) were compared and analyzed according to GDM diagnosis as well to alcohol status. Results: Up to 240 pregnant women accepted to enroll into the study. Alcohol consumption concerned 78 (32.5%) of the women, most of them (61 = 25.42%) being heavy consumers. Risk factors for GDM and Physical and blood glucose characteristics were alike (p not significant) in both consumers and non consumers, except for history of HTA in the family that was significantly more frequent (p = 0.02) among drinkers. GDM's prevalence was 9%. No adverse outcome was more prominent in any subgroup, except Apgar score < 7 at the first minute that was more frequent (p = 0.038) among neonates of GDM mothers. No FAS, neither shoulder dystocia nor neonatal hypoglycemia were diagnosed. When alcohol status was considered, Birthweight ≥ 3800 g was found more frequent (p = 0.0284) in alcohol consumers than in abstainers. Risk of this outcome was three times higher when history of family hypertension was present (odds ratio 2.694; CI: 0.536 -13.544). Conclusions: The prevalence of alcohol consumption by pregnant women of our series (32.5%) seems not to impact the detection of GDM (9%). FAS was not diagnosed. Lack of significant differences in adverse outcomes between GDM and non GDM could be attributed to huge follow-up of GDM women. Influence of alcohol consumption on birth weight mostly in setting of familial history of hypertension remains to be addressed.

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Section: Commentsmentioning

confidence: 44%

“…Mullally et al [13] also observed only 3 cases (0.005%) of FAS among women whose up to 81% were alcohol consumers.…”

Section: Commentsmentioning

confidence: 99%

Effect of maternal alcohol consumption on gestational diabetes detection and mother-infant’s outcomes in Kinshasa, DR Congo

Barthélémy¹,

Andy²,

Roger³

2011

OJOG

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“…Public health campaigns are needed that would educate and provide healthy lifestyle choices with advice on diet, exercise, alcohol, smoking, medications and folic/ multivitamin supplementation. Further qualitative research is needed to explore in-depth the dilemmas that women and their health care providers face during pregnancy (2,7).…”

Section: Discussionmentioning

confidence: 99%

“…Many women continue to consume alcohol in pregnancy despite an increasing body of evidence suggesting harm to the foetus (7,8). Maternal smoking during pregnancy also poses a significant risk to the unborn child.…”

Section: Introductionmentioning

confidence: 99%

Characteristics of health behaviours and health status indicators among pregnant women in Slovenia

et al. 2017

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Navade, povezane z zdravjem in socialno demografske značilnosti nosečnic v Sloveniji tina kek,1 nataša karas kuželički,2 Irena Mlinarič raščan,2 ksenija Geršak 1,3 IzvlečekIzhodišča: Nosečnost je obdobje, ko ženske za zdravje bodočega otroka kritično presojajo in ocenjujejo svoje zdravje ter z zdravjem povezane navade. Skupaj z zdravstvenimi delavci se srečujejo s šte-vilnimi tveganji in odločitvami, ki postanejo veliko kompleksnejše, saj je v igri vpliv na dva organizma. Namen članka je pregled ter iskanje morebitnih povezav med zdravjem, z zdravjem povezanimi navadami ter socialno demografskimi dejavniki v nosečnosti, ki so jih poročale sodelujoče ženske.Metode: Podatke študije smo pridobili v okviru raziskovalnega projekta Analiza bioloških označe-valcev presnove folatov pri ugotavljanju tveganja za nastanek napak nevralne cevi, orofacialnih shiz ter prirojenih srčnih napak, ki je potekal od maja 2013 do septembra 2015. Vprašalnik o maternalnem zdravju, z zdravjem povezanih navadah ter socialno demografskih karakteristikah je izpolnilo 450 sodelujočih žensk. Podatki zajemajo nosečnosti, ki datirajo od osemdesetih let prejšnjega stoletja pa do leta 2015.Rezultati: Mlajše in manj izobražene ženske so pogosteje poročale o kajenju med nosečnostjo, medtem ko so starejše, bolj izobražene ter nulipare ženske v višjem odstotku jemale folatne/multivitaminske dodatke. Opazili smo U-obliko porazdelitve uporabe zdravil (brez recepta in na recept) glede na stopnjo izobrazbe. Najvišji odstotek uporabe so imele ženske z najvišjo stopnjo izobrazbe (magisterij/doktorat) in ženske z doseženo najnižjo stopnjo izobrazbe (osnovna šola). Večjo uporabo zdravil med nosečnostjo so poročale tudi starejše ženske. Opazili smo trend višanja uporabe zdravil in folatnih/multivitaminskih pripravkov kot tudi incidence nosečniške sladkorne bolezni preko preiskovanega obdobja, z najvišjo incidenco v zadnjih desetletjih. Višjo pojavnost kroničnih bolezni smo opazili v skupini multiparih žensk.Zaključki: V navadah povezanih z zdravjem nosečnic obstajajo precejšnje socialno demografske razlike. Za izboljšanje zdravja so potrebni izboljšani javno zdravstveni ukrepi in individualno svetovanje, da lahko ustrezno naslovimo specifične potrebe socialno demografskih skupin z višjim tveganjem za neželene izide nosečnosti. AbstractBackground: Pregnancy is a period when women reconsider their own health and health related behaviour for the sake of their future child. Along with their health providers, they are faced with a number of risk assessments and decisions, which become far more complex as their effect on two organisms rather than one is at play. This paper provides an overview of possible associations between self-reported health status, health behaviours and socio-demographics during pregnancy. 296zdrav vestn | julij -avgust 2017 | letnik 86 reProdukCIja človeka Methods: Study data were obtained from the case-control research project "Analysis of folate metabolism biomarkers in the risk assessment for neural tube defects, orofacial clefts and cong...

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“…Accordingly, reports on the prevalence of women consuming alcohol in pregnancy vary between 5% and 81% (Senecky et al, 2011, Bakker et al, 2010, Thanh and Jonsson, 2010, Cheng et al, 2011, Chung et al, 2010, Mullally et al, 2011, Tarrant et al, 2011, Freire et al, 2009, Ho and Jacquemard, 2009. Such variation may reflect the differing population groups being studied, differing measures of alcohol and the timing of these measures relative to pregnancy gestation.…”

Section: Scope Of the Problemmentioning

confidence: 99%

Women’s mental health following the birth of a child: a life course approach

Kingsbury¹

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Does the experience of being pregnant, giving birth and becoming a mother affect women's mental health over their reproductive life course? Much of the research on maternal mental health has focused on the perinatal period. In recent times, research has extended to patterns of women's mental health over the years following the birth of their baby. In this thesis, associations between women's experiences around pregnancy and giving birth, and patterns of their mental health impairment in the years following the baby's birth, are examined.Participants: Three datasets were used for this thesis. The primary dataset was the Mater and Methods: Six studies are the core contribution of this body of research. These studies, five cohort studies and one cross-sectional study, addressed the thesis' aims and objectives.Studies' outcome measures generally related to women's mental health, rated by the Delusions-Symptoms-States-Inventory: state of Anxiety and Depression (DSSI/sAD) (Bedford et al., 1976) and assessed at time-points post-birth. In three studies, women's DSSI depression measures at various time-points were combined to create depressive-symptoms trajectories. The Mental Disorder Screening Tool (MDST), constructed from women's DSSI/sAD responses (Saiepour et al., 2014) and measuring mental health impairment, was an outcome measure for one study. Another study's outcomes were based on women's reported alcohol consumption before pregnancy and at their first clinic visit. A broad range of predictor and potential confounding variables, taken at different MUSP survey phases, were included in the studies' analyses. Descriptive and inferential analyses were used. Univariate and multivariable regression analysis derived odds ratios and relative risk ratios with 95% confidence intervals. Pregnancy and birth events were found to contribute little to women's experience of depression. Pregnant women who experienced stressful life events (that is, financial, housing and relational events), were at higher risk of having depressive symptoms over the 27-year period. The proportion of women with mental health impairment was higher at 21 years post birth than at six months post birth. Women whose offspring had behaviour problems were themselves at risk of mental health impairment at 21 years post birth. As well, mental health problems in pregnancy; young motherhood; not completing high school and low family income; and having poor social networks around baby's birth, and marital discord in pregnancy, predicted women's poorer mental health over time. Today's pregnant women are more likely to be older and have higher body mass indexes, more likely to be anxious but not depressed, and more are sure about wanting to be pregnant, compared to pregnant women from previous decades. Today's pregnant women are also less likely to be smokers but are more often consuming alcohol prior to pregnancy, though they substantially reduce their alcohol consumption in pregnancy. Socio-economic disadvantage and psychosocial problems in pregnancy ...

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Prevalence, predictors and perinatal outcomes of peri-conceptional alcohol exposure - retrospective cohort study in an urban obstetric population in Ireland

Cited by 78 publications

References 16 publications

Effect of maternal alcohol consumption on gestational diabetes detection and mother-infant’s outcomes in Kinshasa, DR Congo

Effect of maternal alcohol consumption on gestational diabetes detection and mother-infant’s outcomes in Kinshasa, DR Congo

Characteristics of health behaviours and health status indicators among pregnant women in Slovenia

Women’s mental health following the birth of a child: a life course approach

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