Prevalence of vulvovaginitis and bacterial vaginosis in patients with koilocytosis

Abstract

CONTEXT AND OBJECTIVE: Empirical discussion regarding an association between koilocytosis and vulvovaginitis often occurs. Thus, the objective of this study was to assess the prevalence of microorganisms associated with bacterial vaginosis and vulvovaginitis in women with and without koilocytosis. DESIGN AND SETTING:Analytical cross-sectional study including two cohorts of women (with and without koilocytosis) who attended a cancer hospital in the city of Goiânia, state of Goiás. METHODS:A total of 102 patients entered the study. The whiff test, Gram and Papanicolaou staining and bacterial and fungal culturing were performed. The results were observed using univariate analysis. The odds ratio and confi dence interval (CI) of the variables were calculated; P-values < 0.05 were considered signifi cant. RESULTS:The prevalence of bacterial colonization was similar in patients with and without koilocytosis. The odds ratio for candidiasis was 1.43 (CI 1.05-1.95) and the odds ratio for trichomoniasis was 1.78 (CI 1.49-2.12), in patients with koilocytosis.

Microbiota cérvico-vaginal de ovelhas mestiças e sua susceptibilidade aos antibióticos

“…Entretanto, S. epidermidis foi isolado de seis animais, corroborando com os achados do presente estudo. O isolamento de S. schleiferi na mucosa genital já foi descrita em algumas espécies como em jabutis (Pessoa 2009), cães (Coggan et al 2008) e em humanos (Campos et al 2008), entretanto são escassos estudos referentes a este microrganismo no sistema genital de ovelhas. Bactérias do gênero Micrococcus são descritas como habitantes das mucosas de diversas espécies animais (Gomes 2006, Fornazari et al 2007, Uchôa et al 2009), sendo considerado de baixa patogenicidade (Wunder et al 1976).…”

Evaluation of Cytokines in Endocervical Secretion and Vaginal pH from Women with Bacterial Vaginosis or Human Papillomavirus

“…The necessary sample size for this particular age group of women was estimated by considering the known prevalence of bacterial vaginosis (25%) [5] and vaginal HPV infection (15%) [5, 8, 18]. Based on this calculation and desired test power >80%, the study required 157 women; we further took into account a 10% potential loss to followup and determined that a total of 173 participants should be enrolled in the research study.…”

“…The plates and tubes were immediately placed in an anaerobic jar and transported to the laboratory for processing as described [8]. We also measured the individual's vaginal pH (posterior cul-de-sac), performed an amine test [5], and prepared histological slides for a Pap smear and a Gram stain.…”

“…Bacterial vaginosis (BV) of undefined etiology is an inflammatory and recurring syndrome of the lower genital tract and is considered the most prevalent vaginal imbalance affecting women of reproductive age [4, 5]. BV is characterized by an alteration in the normal vaginal flora, in which the predominant lactobacilli are replaced by various other microorganisms.…”

“…BV is characterized by an alteration in the normal vaginal flora, in which the predominant lactobacilli are replaced by various other microorganisms. Increases in species such as Gardnerella vaginalis , Mobiluncus spp., Bacteroides sp., Prevotella spp., Peptostreptococcus spp., Mycoplasma hominis , or Ureaplasma urealyticum are routinely detected and are accompanied by a subsequent increase in the vaginal pH [5, 6]. Bacterially produced proteases degrade the mucus secreted from the cervix to facilitate the pathogen's ability to contact and breach the protective epithelial barrier [2].…”