Prevalence of vitamin D insufficiency in Swiss teenagers with appendicular fractures: A prospective study of 100 cases

Ceroni, Dimitri; Llana, Rebecca Anderson de la; Martin, Xavier; Lamah, Léopold; Coulon, Geraldo De; Turcot, Katia; Dubois-Ferrière, Victor

doi:10.1007/s11832-012-0446-7

Cited by 25 publications

(23 citation statements)

References 63 publications

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“…However, in Swiss teenagers with appendicular fractures, there was no difference between healthy individuals and those with fractures in vitamin D levels or lumbar or heel BMD, nor was there a difference between fracture sites. Despite a high prevalence of hypovitaminosis D, there was no association between vitamin D levels and spinal BMD[17]. Low BMD increases the risk of failure in surgical procedures, especially the application of hardware, for instance in spinal fusion.…”

Section: Vitamin D In Spine Surgerymentioning

confidence: 99%

Vitamin D and spine surgery

Mabey¹,

Singhatanadgige²,

Yingsakmongkol³

et al. 2016

WJO

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Vitamin D is crucial for musculoskeletal health, maintenance, and function. Vitamin D insufficiency is common among patients undergoing spine surgery and the ideal vitamin D level for spine surgery has yet to be investigated. There is a high prevalence of hypovitaminosis D in patients with musculoskeletal pain regardless of surgical intervention. With the frequency and costs of spine surgery increasing, it is imperative that efforts are continued to reduce the impact on patients and healthcare services. Studies into vitamin D and its associations with orthopaedic surgery have yielded alarming findings with regards to the prevalence of vitamin D deficiency. Importantly, altered vitamin D status also contributes to a wide range of disease conditions. Therefore, future investigations are still essential for better understanding the relationship between vitamin D and spine surgery outcomes. Whilst further research is required to fully elucidate the extent of the effects of hypovitaminosis D has on surgical outcomes, it is strongly advisable to reduce the impacts by appropriate vitamin D supplementation of deficient and at-risk patients.

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Section: Vitamin D In Spine Surgerymentioning

confidence: 99%

Vitamin D and spine surgery

Mabey¹,

Singhatanadgige²,

Yingsakmongkol³

et al. 2016

WJO

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“…The findings of these studies are somewhat inconsistent, both at the same skeletal sites across studies and at different skeletal sites within the same population [33,66,67,[88][89][90][91][92][93][94][95][96][97][98][99][100][101] (Table 3). However, there is considerable variation in the age of study participants, geographic location and the confounding factors considered.…”

Section: Vitamin D Status and Bmd In Childhood And Adolescencementioning

confidence: 99%

Vitamin D and skeletal health in infancy and childhood

et al. 2014

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During growth, severe vitamin D deficiency in childhood can result in symptomatic hypocalcaemia and rickets. Despite the suggestion from some studies of a secular increase in the incidence of rickets, this observation may be driven more by changes in population demographics than a true alteration to age, sex and ethnicity-specific incidence rates; indeed rickets remains uncommon overall and is rarely seen in fair-skinned children. Additionally, the impact of less severe vitamin D deficiency and insufficiency has received much interest in recent years, and in this review we consider the evidence relating vitamin D status to fracture risk and bone mineral density (BMD) in childhood and adolescence. We conclude that there is insufficient evidence to support the suggestion that low serum 25-hydroxyvitamin D [25(OH)D] increases childhood fracture risk. Overall, the relationship between 25(OH)D and BMD is inconsistent across studies and across skeletal sites within the same study; however there is evidence to suggest that vitamin D supplementation in children with the lowest levels of 25(OH)D might improve BMD. High quality randomised trials are now required to confirm this benefit.

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“…The results of James et al (19) were limited to children with an upper extremity fracture and showed a vitamin D deficiency in 24%. Ceroni et al (20) included 100 adolescent (between 10 and 16 years) patients with upper- or lower-limb fractures and found that 12 (12%) were vitamin D deficient. We documented a prevalence of 46% vitamin D deficiency in 98 children between 10 and 16 years.…”

Section: Discussionmentioning

confidence: 99%

“…We documented a prevalence of 46% vitamin D deficiency in 98 children between 10 and 16 years. Ceroni et al (20) only included surgically treated children in their series and measured the vitamin D concentration at once after storage, which may explain the difference in prevalence. Similar to our study, Contreras et al (17) did not limit inclusion to the study to age or fracture location, although they did not report the patients’ skin type.…”

Section: Discussionmentioning

confidence: 99%

“…A recent study showed that a lower vitamin D status is associated with fractures requiring surgery, but not with the occurrence of fractures (18). Although the prevalence of vitamin D deficiency in children in the general population has been well described (7,8), the prevalence of vitamin D deficiency in the pediatric fracture population is less often reported with a wide variation ranging from 8% to 47% (Table 1) (14,15,17,18,19,20,21). …”

Section: Introductionmentioning

confidence: 99%

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Vitamin D Deficiency in Pediatric Fracture Patients: Prevalence, Risk Factors, and Vitamin D Supplementation

Gorter

Oostdijk²,

Felius³

et al. 2016

Jcrpe

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Objective:Although vitamin D levels are not routinely monitored in pediatric fracture patients, identification of children with a vitamin D deficiency may be clinically relevant because of the potential role of vitamin D in fracture healing. This study aimed to determine the prevalence of vitamin D deficiency in a pediatric fracture population and to identify risk factors for deficiency.Methods:All pediatric patients (<18 years) who were treated for a fracture of the upper or lower extremity from September 2012 to October 2013 in the outpatient setting of a level one trauma center were included in this cross-sectional study. Vitamin D deficiency was defined as a serum calcidiol <50 nmol/L. Potential risk factors for vitamin D deficiency were analysed using multivariable logistic regression analysis.Results:A total of 108 boys (58%) and 79 girls, of a mean age 11.1 years (standard deviation 3.9), who had undergone 189 fractures were included in the study. Sixty-four children (34%) were vitamin D deficient. Of those with follow-up measurements, 74% were no longer deficient after supplementation. Vitamin D status did not influence the occurrence of complications during fracture treatment. Independent risk factors for vitamin D deficiency were older age, season (spring), and a non-Caucasian skin type.Conclusion:Clinicians who treat children with a fracture should inform patients and parents on vitamin D supplementation. Vitamin D measurement and supplementation may be needed for children with a non-Caucasian skin type or for those who present with a fracture during spring months.

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Prevalence of vitamin D insufficiency in Swiss teenagers with appendicular fractures: A prospective study of 100 cases

Cited by 25 publications

References 63 publications

Vitamin D and spine surgery

Vitamin D and spine surgery

Vitamin D and skeletal health in infancy and childhood

Vitamin D Deficiency in Pediatric Fracture Patients: Prevalence, Risk Factors, and Vitamin D Supplementation

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