Prevalence of varicocoele and its association with body mass index among 39,559 rural men in eastern China: a population‐based cross‐sectional study

Liu, J.; Zhang, S.; Liu, M.; Wang, Q.; Shen, Haiping; Zhang, Y.; Yan, Donghai

doi:10.1111/andr.12345

Cited by 12 publications

(39 citation statements)

References 39 publications

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“…We excluded twenty-two studies that did not report the outcome of varicocele or did not provide enough data to calculate the ORs. Finally, we identified eleven full-text articles (12, 14, 18, [24][25][26][27][28][29][30][31] that met the inclusion criteria. The search flow chart is shown in Figure-1, and the characteristics of the eleven included articles are summarized in Table-1.…”

Section: Resultsmentioning

confidence: 99%

The association between body mass index and varicocele: A meta-analysis

et al. 2021

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Objective: Recently, several studies have found that obesity had a protective effect against varicocele, but no meta-analysis has confi rmed this fi nding. Therefore, we conducted this meta-analysis to investigate the association between body mass index (BMI) and varicocele. Material and Methods: We searched for studies in PubMed, Science Direct and the Cochrane Library from inception until February 2018. The association between BMI and varicocele was assessed by pooling the odds ratios (ORs). Results: Eleven eligible studies with a total study population of 1.376.658 participants were included in our analysis. According to BMI, the subjects were defi ned as belonging to the obese, overweight and underweight groups. Our results showed that the obese group had a lower risk of varicocele when compared with the normal weight group (odds ratio [OR] 0.46, 95% confi dence intervals [CIs] 0.37-0.58). Additionally, an overweight BMI had a protective effect against varicocele (OR 0.70, 95% CIs, 0.56-0.86). However, underweight patients had a more than 30% higher risk of varicocele (OR 1.31, 95% CI, 1.04-1.64). Furthermore, there was no publication bias in any of the analyses. Conclusions: Our study demonstrates that BMI is negatively associated with the presence of varicocele.

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Section: Resultsmentioning

confidence: 99%

The association between body mass index and varicocele: A meta-analysis

et al. 2021

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“…A cross‐sectional multicenter study of 7035 young men from six European countries with the median age 19 years showed that the overall prevalence of varicocele was 15.7% (Damsgaard et al ., ). In eastern China, the incidence was 4.83% through the study of 39,559 rural men (Liu et al ., ). And it is a higher incidence of varicocele in the crowd with infertility; a cross‐sectional study showed that the incidence of varicoceles is up to 16.3% in men with fertility requirements who attended an infertility clinic (Dieamant et al ., ), and 26% of infertile men in China suffer from varicocele at present (Zhang et al ., ).…”

Section: Introductionmentioning

confidence: 97%

Relationship between varicocele and platelet indices: changes of mean platelet volume before and after operation

Zhang¹,

Liang

et al. 2019

Andrology

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Background: The correlation between the increased mean platelet volume and varicocele is controversial. Objectives: We designed this research to demonstrate the correlation relationship between varicocele and mean platelet volume by studying the changes of mean platelet volume in patients with varicocele before and after operation. Materials and methods: A total of 317 patients with left unilateral varicocele underwent operation, and 293 healthy adult males were enrolled in the study. We collected diagnostic data for preoperative patients through physical examination, color Doppler ultrasonography, and blood routine, and recorded the follow-up data at 6 months after operation for varicocele. Platelet indices and the degree of varicocele or the diameter of spermatic vein correlation analysis were performed. Mean platelet volume values of preoperative and 6-month postoperative were statistically evaluated. Results: We found that the degree of varicocele and the diameter of spermatic vein were positively correlated with mean platelet volume (p = 0.001 or p < 0.001). When the left unilateral varicocele patients and healthy subjects were compared, there was a significant increase in mean platelet volume (p = 0.003). Mean platelet volume values of 96 varicocele patients who were cured by operation for varicocele after 6 months were decreased significantly more than preoperative (p = 0.039), but 32 varicocele patients of 6month postoperative recurrence could not prove this change (p = 0.930). Discussion and conclusion: Our research proves that mean platelet volume was positively correlated with the degree of varicocele and the diameter of spermatic vein and varicocele patients showed significantly higher mean platelet volume than healthy subjects. The mean platelet volume of varicocele patients cured by operation for varicocele after 6 months was lower than before, but there was no difference in mean platelet volume between 6-month postoperative recurrent patients with preoperative.

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“…When the literature is examined, various studies have shown that the incidence of varicocele is decreased in overweight and obese men [29] [30] [31] [32]. In a large-scale study by Liu et al, it was shown that varicocele grade was decreased with reduced body mass index [22] [28]. In our study, while the patients with a low BMI had a low-grade varicocele, the patients with a high BMI had a high-grade varicocele.…”

Section: Discussionmentioning

confidence: 45%

“…The relationship between adolescent varicocele, weight and BMI is still unclear [22]. Although some studies have revealed a positive correlation between the incidence of adolescent varicoceles and weight gain, it has been shown to be inversely proportional to reduced body mass index [23]- [28].…”

Section: Discussionmentioning

confidence: 99%

Adolescent Varicocele

Çimen¹

2018

OJU

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Introduction: Adolescent varicocele is still a controversial issue in pediatric urology. In this study, we aimed to evaluate adolescent patients with varicocele, who were operated in our clinic, in the light of literature. Materials and Methods: The data of adolescent patients who underwent varicocelectomy between January 2012 and January 2018 in the Urology Clinic of Malatya Training and Research Hospital were examined retrospectively. The age and admission complaint of the patients, the localization of varicocele, the varicocele grade determined by color Doppler ultrasound (US), the presence of testicular atrophy, the height, weight, body mass index of the patients as well as their relationship with each other were evaluated. Results: The mean age of the patients is 14.74 years (10 -17 years). Of the patients, 153 (92.2%) had a left-sided varicocele and 13 (7.8%) had a right-sided varicocele. When admission complaints of the patients were examined, 31 (18.6%) had scrotal pain, 53 (32.2%) had scrotal swelling, 21 (12.6%) had skin bruising, 40 (24%) had dilated veins recognized by the family, and 21 (12.6%) had more than one complaint. When the relationship between varicocele grade and BMI was examined, 13 (35.1%) of the 37 patients with a grade 2 varicocele were lean, 23 (62.1%) were normal weight, and 1 (2.8%) was obese. 12 (17.7%) of the 68 patients with a grade 3 varicocele were lean, 54 (79.4%) were normal weight, and 2 (2.9%) were overweight. 8 (13.1%) of the 61 (36.7%) with a grade 4 varicocele were lean, 46 (75.5%) were normal weight, and 7 (11.4%) were overweight. Conclusion: Adolescent varicocele is still one of the controversial issues today; the diagnosis should be made with the help of physical examination and radiological tests besides the family's application in boys in this age group in order to prevent possible problems.

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Prevalence of varicocoele and its association with body mass index among 39,559 rural men in eastern China: a population‐based cross‐sectional study

Cited by 12 publications

References 39 publications

The association between body mass index and varicocele: A meta-analysis

The association between body mass index and varicocele: A meta-analysis

Relationship between varicocele and platelet indices: changes of mean platelet volume before and after operation

Adolescent Varicocele

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