Prevalence of type-specific human papillomavirus and pap results in Chinese women: a multi-center, population-based cross-sectional study

Abstract

Although HPV18 appeared to be less frequent among population-based samples of China, given the high prevalence of HPV 16 and 18 in high-grade squamous intraepithelial lesion (HSIL) or worse pap abnormalities, prophylactic HPV16/18 vaccines should substantially reduce the burden of cervical cancer in China.

Human Papillomavirus (HPV) Infection in Women Participating in Cervical Cancer Screening from 2006 to 2010 in Shenzhen City, South China

“…Among single HPV subtype infections, HPV16, HPV58, HPV33, HPV43 and HPV52 were the common types. HPV52 were the predominant in the present study, which was consistent with the domestic reports (Bao et al, 2007;Liu et al, 2007;Wu et al, 2013). HPV52 undoubtedly has great significance for the new generation of vaccine development, application and cervical cancer prevention and control.…”

“…Our findings showed a relatively high prevalence of HPV (13.80%) among females in Shenzhen city, and similar ratios were found in Taipei and five areas of mainland China, but higher than that reported in North India, and lower in Italy (Datta et al, 2010;Wang et al, 2010;Guido et al, 2013;Wu et al, 2013). The reasons could be explained by the different detection methodologies, and the ethical, racial, or geographic diversity.…”

Cervical Cancer Screening Among Adult Women in China, 2010

“…Patterns of HPV prevalence differed by age, geographic region, and cytology findings. Researchers believed there was great potential for HPV vaccines, including types 16 and 18, to significantly decrease the cervical cancer burden in China [31].…”

Prevention of human papillomavirus (HPV) infection and cervical cancer in China: How does HPV vaccination bring about benefits to Chinese women?

“…Patterns of HPV prevalence differed by age, geographic region, and cytology findings. (Wu et al, 2013) Efficacy, safety and immunogenicity…”

“…The infection can be detected in more than 95% of carcinoma issues (2). So far, more than 100 different HPV genotypes have been detected, and among them type 16,18,31,33,35,39,45,51,52,56,58,59, and 68 are a high-risk for cervical carcinoma. The most common genotypes among infected women are 16, 18, 31, 58, and 52, accounting for approximately half of HPV infections (3).…”