Prevalence of shigellosis diarrhoea in a paediatrics population: hospital based survey in Bangui, Central African Republic

Abstract

Introduction: Shigellosis is still a major public health problem in sub-Saharan countries, especially among children. Methodology: The prevalence of shigellosis in children presenting with diarrhoea in the Complexe Pédiatrique de Bangui, Central African Republic, was determined. Stools were analyzed in the bacteriology laboratory of the Institut Pasteur de Bangui, Central African Republic, where identification of Shigella species and analysis of antibiotics susceptibility were performed. Results: A total of 15 strains of Shigella were isolated from 156 stools; Shigella flexneri was the only species found. Two infected children died of dehydration. Most strains were resistant to antibiotics except quinolones, which were active on all of these strains. Conclusions: The control of Shigella infections should be reinforced in Bangui, and accurate, affordable and rapid methods of diagnosis would be helpful.

Multiple drug resistance of Campylobacter jejuni and Shigella isolated from diarrhoeic children at Kapsabet County referral hospital, Kenya

“…The infections observed in the 0–11 months’ group might be explained by possible unhygienic food preparation, food storage and feeding of infants as weaned foods get exposed to contamination. On the other hand, less diarrheal infection was observed with increasing age groups which is consistent with other studies, and this might reflect on possible poor immunity among children invariably due to under nutrition increases susceptibility to diarrheal diseases [ 2 , 8 , 9 ].…”

“…Approximately 6.2% of C. jejuni isolates were resistant to norfloxacin, though negligible, points to the emergence of resistance. Comparisons can be made with an increase in cephalosporins resistance rates from 0 to 84% recorded in Thailand and Nigeria as result of inappropriate and indiscriminate use of that class of drugs [ 7 , 9 ]. C ampylobacter jejuni was resistant > 50% of the panel of antibiotics used indicating multiple drug resistance, an appearance which would be a worrying concern globally.…”

“…Over the years, sulphonamides, tetracycline, ampicillin and trimethoprim/sulphamethoxazole have been effective drugs, only to become impotent in the face of emerging resistance [ 1 ]. One class of antibiotics whose clinical efficacy is particularly diminished due to an increase in the prevalence of resistant bacteria are the aminoglycosides such as streptomycin, gentamicin, tobramycin, kanamycin and amikacin [ 9 ]. Previously, a single dose of the quinolones: norfloxacin and ciprofloxacin were effective in treating shigellosis.…”

Prevalence and antibiogram of <i>Shigella</i> and <i>Salmonella spp.</i> from under five children with acute diarrhea in Bahir Dar Town

“…Most mothers nowadays are advised to feed their babies with breast-milk only and not give their babies supplementary food items until the age of 6 months (Abdullahi, 2010). Republic (Manirakiza et al, 2010). This result is lower compared to that reported from Ethiopia (Moges Tiruneh, 2009) and Botswana (Urio et al, 2011), however the prevalence recorded in this study is higher than the prevalence reported from Cameroon (Yongsi, 2008) and Tanzania (Moyo et al, 2011).…”