Prevalence of rhinosporidiosis of the eye and its adnexa in Nepal.

Abstract

This study describes the clinical features, diagnosis, and treatment of rhinosporidiosis of the eye and its adnexa in a series of 76 cases in Nepal and six originating in India. The disease caused by the fungus Rhinosporidium seeberi was seen most frequently in young children between eight and 10 years of age. Males were infected more than females (2.5:1). The conjunctiva was the most common site of infection in 76 (92.68%) of the cases. The lacrimal sac was affected only in six (7.32%) cases. Simple total excision of the conjunctival polyps gave highly satisfactory results in cases of conjunctival sac infections. Except for one patient, there were no recurrences in the76 cases. Meticulous excision of polyps provided a satisfactory result in the treatment of six cases with lacrimal sac infection. Recurrence was noted in one of these six cases followed up to two and a half years after surgery. The conditions diagnosed clinically were confirmed by histopathology. This review of 82 cases is the first such report of rhinosporidiosis from Nepal.

Current Perspectives on Ophthalmic Mycoses

“…Rhinosporidioisis appears to be endemic in the Indian subcontinent (54,199,258,352), but significant numbers of cases have also been reported from Malawi and Kenya (295), northern Serbia (413), Zaire (397), Kuwait (371), and the United States of America (108,169,321). The prevalence of this condition in a south Indian village was reported to be 470 per 100,000 population (61).…”

“…The prevalence of this condition in a south Indian village was reported to be 470 per 100,000 population (61). Children and young adults (up to 30 years of age) living in rural areas, who work in rice fields or bathe in stagnant water, appear to be the most severely affected (61,258,284,295,352,413). Most studies have reported a male preponderance, but one study 764 THOMAS CLIN.…”

“…Outgrowths on palpebral conjunctiva (258, 321, 343, 352,), lacrimal sac (178,199,258,352), lid margins (258), canaliculus, and sclera (226). Conjunctival rhinosporidiosis with associated scleral melting and staphyloma formation recently reported (54).…”

“…In tissue (hematoxylin-eosin stained), usually a granuloma with marked inflammatory cell infiltrate (343,352); chronic, nongranulomatous lesions (295) or absence of inflammatory cell infiltrate (371) occasionally noted. Well-defined spherical bodies, i.e., spherules or sporangia (Fig.…”

Rinosporidiosis conjuntival diagnosticada mediante estudio histopatológico

“…El tratamiento de este cuadro considera la resección completa de la lesión 3,14,15 ; la cual puede ser combinada con crioterapia o cauterización del lecho para evitar recurrencias, aunque se han reportado casos con regresión espontánea 16 .…”