Prevalence of rheumatoid arthritis following COVID-19 vaccine: An autoimmune disorder

Rai, Aneesh; Aashish, None; Priya,; Karmani, Sundiya; Abbas, Waseem; Khatri, Govinda

doi:10.1016/j.amsu.2022.104628

Cited by 3 publications

(2 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several mechanisms have been proposed for the induction of autoimmunity in these patients, including molecular mimicry, epitope spreading, bystander activation, or superantigenic T-cell activation. Although the exact mechanism by which these vaccines induce autoimmune disease is not yet known, we have seen an increasing number of reports of arthralgias and arthritis after COVID-19 vaccination in recent years, which have also been explained by molecular mimicry [28,29].…”

Section: Discussionmentioning

confidence: 99%

New Onset Autoimmune Diseases after the Sputnik Vaccine

et al. 2023

View full text Add to dashboard Cite

The vertiginous advance for identifying the genomic sequence of SARS-CoV-2 allowed the development of a vaccine including mRNA-based vaccines, inactivated viruses, protein subunits, and adenoviral vaccines such as Sputnik. This study aims to report on autoimmune disease manifestations that occurred following COVID-19 Sputnik vaccination. Patients and Methods: A retrospective study was conducted on patients with new-onset autoimmune diseases induced by a post-COVID-19 vaccine between March 2021 and December 2022, in two referral hospitals in Mexico City and Argentina. The study evaluated patients who received the Sputnik vaccine and developed recent-onset autoimmune diseases. Results: Twenty-eight patients developed recent-onset autoimmune diseases after Sputnik vaccine. The median age was 56.9 ± 21.7 years, with 14 females and 14 males. The autoimmune diseases observed were neurological in 13 patients (46%), hematological autoimmune manifestations occurred in 12 patients (42%), with thrombotic disease observed in 10 patients (28%), and autoimmune hemolytic anemia in two patients (7.1%). Rheumatological disorders were present in two patients (7.1%), and endocrine disorders in one patient (3.5%). Principio del formulario Conclusion: Although the COVID-19 Sputnik vaccine is generally safe, it can lead to adverse effects. Thrombosis and Guillain-Barre were the most frequent manifestations observed in our group of patients.

show abstract

Section: Discussionmentioning

confidence: 99%

New Onset Autoimmune Diseases after the Sputnik Vaccine

et al. 2023

View full text Add to dashboard Cite

show abstract

“…This study was a cross-sectional and observational study based on a web-based survey between 22 March 2021 and 17 May 2021. In this study, 3% of the 696 patients reported a medically confirmed SLE flare after vaccination [ 57 ]. Flares or disease deterioration in 3% to 19% (depending on the study) of patients with autoimmune diseases are not irrelevant.…”

Section: Safety Of Covid-19 Vaccines In People With Autoimmunity and ...mentioning

confidence: 99%

Safety of COVID-19 Vaccines in Patients with Autoimmune Diseases, in Patients with Cardiac Issues, and in the Healthy Population

2023

View full text Add to dashboard Cite

The coronavirus disease 2019 (COVID-19) has been a challenge for the whole world since the beginning of 2020, and COVID-19 vaccines were considered crucial for disease eradication. Instead of producing classic vaccines, some companies pointed to develop products that mainly function by inducing, into the host, the production of the antigenic protein of SARS-CoV-2 called Spike, injecting an instruction based on RNA or a DNA sequence. Here, we aim to give an overview of the safety profile and the actual known adverse effects of these products in relationship with their mechanism of action. We discuss the use and safety of these products in at-risk people, especially those with autoimmune diseases or with previously reported myocarditis, but also in the general population. We debate the real necessity of administering these products with unclear long-term effects to at-risk people with autoimmune conditions, as well as to healthy people, at the time of omicron variants. This, considering the existence of therapeutic interventions, much more clearly assessed at present compared to the past, and the relatively lower aggressive nature of the new viral variants.

show abstract