Prevalence of oral lichen planus in diabetes mellitus according to the type of diabetes

Petrou-Amerikanou, C; Markopoulos, Anastasios K.; Belazi, Maria; Karamitsos, Dimitrios T.; Papanayotou, P

doi:10.1111/j.1601-0825.1998.tb00253.x

Cited by 63 publications

(65 citation statements)

References 22 publications

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“…In the oral cavity, manifestations of diabetes can include a dry or burning mouth, periodontal diseases, bone loss, dental abscesses, fungal and bacterial infections, oral lichen planus and delayed wound healing. 1,2 Immunoglobulin A (IgA) and immunoglobulin G affect oral cavity microorganisms in the saliva, gingival sulcular fluid and plasma. 3 These antibodies prevent bacterial metabolism and adhesion of microorganisms to the oral tissue.…”

Section: Advances In Patient Care -Determination Of the Salivary Compmentioning

confidence: 99%

“…Several studies have sought to determine salivary flow rates and components that can affect the progression, symptoms and varieties of oral changes in diabetic patients. 1,2,5 Overall, determining the salivary components of diabetic patients can be useful in detecting and managing their oral manifestations. 5 Previous research has assessed s-IgA levels and oral conditions among diabetic patients.…”

Section: Advances In Patient Care -Determination Of the Salivary Compmentioning

confidence: 99%

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Evaluation of Salivary Secretory Immunoglobulin A Levels in Diabetic Patients and Association with Oral and Dental Manifestations

Kakoei

Hosseini

Haghdoost

et al. 2015

SQUMJ

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abstract:Objectives: Oral and dental manifestations in diabetic patients can arise due to numerous factors, including elevated salivary secretory immunoglobulin A (s-IgA) levels. This study aimed to evaluate s-IgA concentrations in patients with type 2 diabetes mellitus (T2DM) and to investigate the association between s-IgA levels and oral and dental manifestations of T2DM. Methods: This cross-sectional descriptive study was carried out between October 2011 and September 2012 in Kerman, Iran, and included 260 subjects (128 patients with T2DM and 132 healthy controls). Unstimulated salivary samples were collected from all subjects and s-IgA levels were determined using the immunoturbidimetric method. The oral cavities and teeth of T2DM patients were evaluated for oral and dental manifestations. Results: Both diabetic and control subjects with higher concentrations of s-IgA had significantly higher numbers of decayed, missing or filled teeth (DMFT) and periodontal index (PDI) scores (P <0.050). s-IgA levels were significantly higher in subjects with oral candidiasis (P <0.050). Among diabetic patients, significantly higher s-IgA levels were concomitant with xerostomia and denture stomatitis (P ≤0.050). There were no significant differences between s-IgA concentrations and other oral or dental manifestations in either group. Conclusion: Individuals with a greater number of DMFT, a higher PDI score and oral candidiasis had significantly higher s-IgA levels. s-IgA levels were not significantly higher among diabetic patients in comparison to the control group. However, significantly higher s-IgA levels occurred with xerostomia and denture stomatitis in diabetic patients. In addition, s-IgA was significantly higher in patients with uncontrolled diabetes compared to those with controlled diabetes.

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Section: Advances In Patient Care -Determination Of the Salivary Compmentioning

confidence: 99%

Section: Advances In Patient Care -Determination Of the Salivary Compmentioning

confidence: 99%

Evaluation of Salivary Secretory Immunoglobulin A Levels in Diabetic Patients and Association with Oral and Dental Manifestations

Kakoei

Hosseini

Haghdoost

et al. 2015

SQUMJ

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“…The relationship between diabetes and oral lichen planus and dental caries is less obvious; several studies have shown widely diverging results. [4][5][6][7] A few studies have suggested that decrease salivary flow results from the use of certain drugs, which would result in changes within the mouth, leading to caries, periodontal disease, and soft tissue alterations; the latter may foster invasion by opportunistic microorganisms. Several types of drugs may cause a subjective feeling of dry mouth, or may induce low salivary flow; these include anticholinergics, antidepressants, diuretics, antihistamines, myorelaxants, diazepinic drugs, and sympatheticomimetics such as hypotensive drugs.…”

Section: Introductionmentioning

confidence: 99%

Clinical study of the oral manifestations and related factors in type 2 diabetics patients

Sousa¹,

Costa²,

Roncalli³

2011

Braz. j. otorhinolaryngol. (Impr.)

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di abetes Mellitus (dM) is reported with and associated to oral alterations, with conflicting results.The aim of this study was to identify the prevalence of oral soft tissue alterations in type 2 diabetes mellitus patients. Material and Methods:Socioeconomic variables, gender, heredity, capillary glucose control and local factors (prosthesis, dry mouth sensation) were analyzed in 196 diabetic and non-diabetic patients enrolled in HiperdiA, at 41 Health units of natal, Brazil.Study Design: A case study. Results:The last blood glucose mean was 177.0 mg/dl for diabetics and 89.46 mg/dl for nondiabetics. Mean capillary blood glucose was elevated in diabetics (215.95 mg/dl); it was 102.31 mg/dl in non-diabetics. The family history confirmed the heredity nature of the disease in 68.8% of diabetic patients (n = 66) (p < 0.001); salivary flow was 49% (n = 47) in diabetics, and 34% (n = 34) in non-diabetics. Candidiasis was present in 30.5% of diabetic patients (n=29) and 36% of nondiabetics (n=36). Both groups had lesions in the palate -81.4% (n = 35) in diabetics, and 71.1% in non-diabetics (n = 27) (p = 0.68). Conclusion:The alterations are not related to diabetes and are present independently of having or not type 2 diabetes Mellitus. Braz J Otorhinolaryngol. 2011;77(2):145-52. ORIgInAL ARTIcLE BJORL

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“…Oral lichen planus (OLP) is a skin disorder that produces lesions in the mouth. OLP is reported to occur more frequently in patients with type1 diabetes compared to type 2 diabetes 90 . The reason for this is that type 1 diabetes is considered an autoimmune disease, and OLP has been reported to have an underlying autoimmune mechanism.…”

Section: Oral Mucosal Diseasementioning

confidence: 99%

“…Both lichen planus and recurrent apthous stomatitis have been reported to occur in patients with diabetes 90,91 . Oral lichen planus (OLP) is a skin disorder that produces lesions in the mouth.…”

Section: Oral Mucosal Diseasementioning

confidence: 99%

Different oral manifestations of diabetes mellitus and its complications a review

Kadiyala¹,

Kumar²

2017

Int j curr adv res

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Objective: To relate different oral manifestations and oral complications of diabetes mellitus Background: Diabetes mellitus is a chronic lifestyle disease affecting all age groups. It is one of the leading causes of mortality and morbidity worldwide. The term "diabetes mellitus" describes a group of disorders characterised by elevated levels of glucose in the blood and abnormalities of carbohydrate, fat and protein metabolism. A number of oral diseases and disorders have been associated with diabetes mellitus, and periodontitis has been identified as a possible risk factor for poor metabolic control in subjects with diabetes. The article will speak in depth about the complications of diabetes mellitus. This article aims to review and increase the awareness of oral manifestations and complications of diabetes mellitus and to stimulate research on the subject. Reason: It is important to know the different oral manifestations of diabetes mellitus to prevent its complications at the early stages. INTRODUCTIONDiabetes mellitus is a growing public health concern and a common chronic metabolic disease worldwide [1][2][3][4] . Diabetes mellitus represents a group of metabolic diseases that are characterised by hyperglycaemia due to a total or relative lack of insulin secretion and insulin resistance or both. The metabolic abnormalities involve carbohydrate, protein and fat metabolism. Diabetes mellitus affects all age groups, but is more common in adults. The World Health Organization (WHO) has recently declared it to be a pandemic 2 . Its prevalence has increased dramatically over the past few decades and it is expected to triple in the next decade. Diabetes mellitus is considered a leading cause of death due to its microvascular and macrovascular complications 5,6 . The most common types of diabetes are type 1 (insulin dependent) and type 2 (non-insulin-dependent) 7,8 . Type 2 is the more prevalent type. Countries with the highest rates of diabetes in the Eastern Mediterranean region and the Middle East are the United Arab Emirates, Saudi Arabia, Bahrain, Kuwait and Oman 9. Oman is one of the countries that has a high prevalence of diabetes mellitus, especially type 2 diabetes, and its prevalence is expected to increase in the next twenty years 10,11 .Various inflammatory diseases and soft tissue pathologies in oral cavities are associated with diabetes mellitus [12][13][14] . However, awareness of these complications is lacking worldwide [15][16][17][18] . Periodontal diseases have been proposed as the sixth most prevalent complication of diabetes mellitus following the other diabetic complications 19 . It has been reported as a more frequent oral complication of diabetes compared to other oral manifestations such as dry mouth and caries. Periodontitis is more frequent and severe in patients with diabetes with poor glycaemic control. Early identification and/or management of these oral manifestations may help in the early diagnosis of diabetes and in attaining better glycaemic control 20 . Therefore, diabetic oral c...

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Prevalence of oral lichen planus in diabetes mellitus according to the type of diabetes

Cited by 63 publications

References 22 publications

Evaluation of Salivary Secretory Immunoglobulin A Levels in Diabetic Patients and Association with Oral and Dental Manifestations

Evaluation of Salivary Secretory Immunoglobulin A Levels in Diabetic Patients and Association with Oral and Dental Manifestations

Clinical study of the oral manifestations and related factors in type 2 diabetics patients

Different oral manifestations of diabetes mellitus and its complications a review

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