Prevalence of Ocular Surface Symptoms, Signs, and Uncomfortable Hours of Wear in Contact Lens Wearers: The Effect of Refitting with Daily-Wear Silicone Hydrogel Lenses (Senofilcon A)

Abstract

Most soft lens wearers encounter clinically significant signs or symptoms with their current contact lenses. Refitting with new-generation silicone hydrogel lenses (senofilcon A) can alleviate some of these common problems.

Predicting success with silicone-hydrogel contact lenses in new wearers

“…Fluorescein TBUT is strongly associated with NIBUT so its predictive abilities are largely redundant. The NIBUT and OSDI metrics are quick to obtain and can aid communication with the patient to examine other aspects related to contact lens wear success such as motivation [44][45] and lens material properties [46][47][48][49] with an aim to reduce contact lens drop-out. [3][4]…”

The influence of end of day silicone hydrogel daily disposable contact lens fit on ocular comfort, physiology and lens wettability

“…Dry eye symptoms are the most common complaint [1,4], with over 70% of wearers reporting symptoms late in the day [2], and approximately one-third of these discontinuing lens wear as a result [8]. However, the relationship of discomfort with respect to changes in lens fit towards the end of the day has not been documented.…”

“…Furthermore, patients generally report comfortable wearing times of about 1 to 1.5 h less than their total wearing time and this appears to be a factor influencing overall wearing time in a proportion of contact lens wearers [1,3]. Consequently, there is a need to understand the changes occurring in the lens-eye relationship towards the end of the wearing day.…”

“…However, the assessment of lens fit in clinical practice is typically made only after a few minutes on initial trial and at aftercare appointments, taking place, at most, after a working day. The average duration of contact lens wear, though, has been reported to be around 13-14 h a day [1][2][3], with approximately 25% of wearers reporting wearing their contact lenses for 16 h, and about 6% wearing their lenses for 17 h a day or more [1].…”

Hydrogel Contact Lenses Surface Roughness and Bacterial Adhesion

“…Developments in soft contact lens materials continue to be an important issue, since the performance and comfort of a contact lens will depend on the material, its surface architecture and the quality of the lens manufacturing process (Lorentz et al, 2007;Riley et al, 2006;Guillon and Maissa, 2007). In addition, the performance of contact lenses does not remain constant over time and lens surface changes induced by wear will affect their performance and determine a need to replace the lens.…”