Prevalence of non albicans Candida in diabetic subjects and its extracellular enzymatic profiles

Abstract

Epidemiology of Candidiosis their prevalence, identification and evaluation of extra cellular enzymes patterns in non albicans Candia group from the oral washings of diabetic subjects. Materials and Methods: A total of 125 oral samples were collected and analyzed. The Candiad species were identified by means of morphological and by molecular methods. The production of virulence factors assessed by using standard protocols. Results: Total of 70 different yeast like fungal strains were isolated and identified. The selected 6 virulence factors were investigated and compared critically among the NAC species. The overall observations were indicating that the virulence factors are fluctuated randomly with in the strains tested. Maximum extent of the virulence factors were reported as Phospholipase [Candida parapsilosis], protease [Candida tropicalis-2, Candida parapsilosis], Haemolysin [Candida tropicalis-3], Coagulase [Candida tropicalis-3], and Biofilm formation [Candida parapsilosis] respectively.Conclusions: In the present study we focused mainly on NAC species and their credible factors responsible for the progression of infections in diabetic subjects.

Dipodascus capitatus: A rare and emerging yeast like fungal infection in immuno-compromised subjects

“…1 In observation, the high incidence recorded by the non-albicans species, rather Candida albicans, would be alarming as they may be resistant to antifungal therapy by some antifungal agents. 2 Rhodotorula is one of the primary yeast-like fungi and belongs to the family of Sporidiobolaceae of the phylum Basidiomycota, a significant cause of fungemia caused by catheters in immune-compromised patients, especially patients with HIV infection/ different carcinoma and patients with undergone organ transplantation. The host's immune status would be a crucial determinant of patients at risk.…”