is a typical inhabitant of humans, especially on the skin, oral cavity, and respiratory tract. Fungi previously considered harmless colonizers (Opportunistic) are emerging as new fungal pathogens, particularly in an immune-compromised state. Infection caused by is rare, and the treatment procedures are quite difficult. Here we reported the information on patients with chronic diabetic conditions. The fungus was isolated from oral washings, the phenotypic identification was based on mycological methods, the molecular marker was based on 18S r RNA sequencing, and the susceptibility test was conducted by micro-dilution technique. The present study mainly focused on quantifying virulence factors, and their activity is expressed in the form of hemolysin protease (1.812 mg/ml). Fungal infections in these patients are often severe, rapid progressive, and challenging to identify, including diagnostic and therapeutic modalities required to provide better patient care.
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