Prevalence of nasal carrier staphylococcus aureus and their antibiotic resistance patterns among health care working at Imam Reza Hospital in Bojnurd

Abstract

Background & Objectives: Staphylococcus aureus is the most common bacteria in nosocomial infections. Nosocomial infections which caused by this bacterium in recent years, considerably, have been increased. This study was conducted in aim of prevalence of Staphylococcus aureus nasal carriage and antibiotic resistance patterns in health care workers, in Imam Reza hospital in Bojnurd. Materials and Methods: A cross-sectional study was conducted on a total of 200 health care workers for 4 months. Nasal swabs were collected. After detection of Staphylococcus aureus isolates, the susceptibility to commonly used antibiotics was determined by disk diffusion method. Methicillin disk diffusion method was applied for detection of methicillin-resistant strains. Results: From 200 patients, 22 (11%) were nasal carrier of Staphylococcus aureus, and 3 of these (13.6%) were resistant to methicillin. In this study, the results indicated that from three nasal methicillin-resistant strains, two were resistant to vancomycin. Conclusions: Presence of nasal carriers, indicated presence of methicillin resistant S. aureus in hospital personnel of Imam Reza in Bojnurd. Although the prevalence of S. aureus nasal carriage was not very high, otherwise, with no attention, presence of MRSA, indicated wide distribution. We advice control measures for prevent MRSA transmission in high risk persons.

Prevalence of Staphylococcus aureus nasal carriers and antibiotic resistance among staff of clinical wards in Nikuee Hospital, Qom, Iran, in 2012

“…In the present study, 100% susceptibility of isolates to vancomycin was observed. This finding was in agreement with that of previous reports in Iran (10,14,17 (11,14,29). The highest resistance rate to penicillin was consistent with previous studies in Iran and other countries (15,30,31).…”

“…The prevalence of MRSA carriers ranged from 3% to 30% in Iran, according to several reports (15). Data obtained in this study on the prevalence of S. aureus carries (33.6%) was consistent with the results of the studies by (10,11,(15)(16)(17). Nevertheless, our findings demonstrated lower prevalence of S. aureus carriers than the finding of Rashidian et al in Sanandaj (43%) (12).…”

“…Carriage of S. aureus in the nares has been detected in investigations in different countries including France (35.52%), Northeast Ethiopia (28.8%), Saudi Arabia (25.4%), China (21.6%), and Nepal (15.7%) (24)(25)(26)(27)(28). In different studies in Iran, the frequency of nasal carriage of S. aureus in HCWs was reported between 11% in Bojnurd, Iran, and 43% in Sanandaj, Iran (11,15). The prevalence of MRSA carriers ranged from 3% to 30% in Iran, according to several reports (15).…”

“…The average rate of nasal carriers of S. aureus and MRSA among HCWs has been reported to be 23.7% and 4.6%, respectively (9). The prevalence of nasal carriage of S. aureus among hospital personnel reported by several studies in Iran varied from 11% to 43% (10)(11)(12)(13)(14)(15)(16). However, no data have been provided on HCWs of hospitals in Qom, Iran, until now.…”