Prevalence of Migraine Headaches in Patients With Congenital Heart Disease

Truong, Tam; Slavin, Leo; Kashani, Ramin; Higgins, James; Puri, Aarti; Chowdhry, M.; Cheung, Philip Y.; Tanious, Adam; Child, John S.; Perloff, Joseph K.; Tobis, Jonathan M.

doi:10.1016/j.amjcard.2007.08.047

Cited by 34 publications

(22 citation statements)

References 24 publications

(17 reference statements)

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“…A study carried out on adults with congenital heart disease described an increased prevalence of migraine compared to controls with acquired cardiovascular diseases (45.3 vs. 11%; p \ 0.001) [31]. Migraine frequency was highest among congenital heart disease subjects with rightto-left shunt (52%) followed by those with left-to right shunt (44%).…”

Section: Cardiac Comorbiditymentioning

confidence: 98%

Chronic migraine: comorbidities, risk factors, and rehabilitation

2010

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Migraine is a serious illness with a spontaneous clinical evolution into a chronic form. In some episodic migraines, increase of crises frequency modifies the headache pattern in the chronic form, defined as chronic migraine (CM), with headache frequency of 15 days/month. One-year prevalence of CM includes around 2-4% of the general population. Migraine progression from episodic to chronic form is realized through a period of time involving several months or years, during which an increase of attack frequency occurs. Migraine shows a wide spectrum of comorbidities, including cardiocerebral, vascular, psychiatric, metabolic, neurologic as well as other pathologies. The single/multiple presence of such comorbidities represents a fixed factor in the process of chronicization into CM. Risk factors including medication overuse headache (MOH), obesity, and lifestyle cooperate in the evolution process to CM. MOH is the most severe complication of CM, and similarly to CM its appearance is gradual. Both CM and MOH show particular genetic background able to favor the appearance of chronicity and abuse. Rehabilitation consists of drug withdrawal procedures, re-prophylaxis through administration of innovative drugs, such as OnabotulinumtoxinA and/or topiramate, to avoid relapsing attacks, and behavioral strategies to minimize the role of risk factors. The initial relief step for drug abusers always relies in drug withdrawal. The feasible diagnostic setting for a CM tailored treatment based on the application of pharmacogenomics will allow us to predetermine the efficacy of single old and new drugs by avoiding abuse due to non-responsivity of the acute drug.

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Section: Cardiac Comorbiditymentioning

confidence: 98%

Chronic migraine: comorbidities, risk factors, and rehabilitation

2010

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“…Another medical condition of interest is the complaint of headaches in Fontan survivors. Headaches have obtained recent attention as a frequently identified subjective complaint 24,25 . In this study, 50% of the participants complained of frequent headaches or migraines.…”

Section: Discussionmentioning

confidence: 76%

Clinical Profile of the Adolescent/Adult Fontan Survivor

Pike

Evangelista

Doering

et al. 2011

Congenital Heart Disease

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Objectives The study aims to describe the clinical profile of the adult Fontan survivor and identify the worries, symptoms, and the impact of cardiac surveillance most commonly experienced. Design A descriptive, cross-sectional design was used. Setting The study was performed in outpatient adult and pediatric cardiology clinics in university-affiliated and private practice offices. Patients Fifty-four adolescent and adult patients with single ventricle congenital heart disease who have undergone the Fontan procedure participated in the study. The mean age was 26 ± 9 years with 52% female and 63% Caucasian. Outcome Measures Demographic and clinical data were obtained by a standard intake form and retrospective chart reviews. The Congenital Heart Disease TNO/AZL Adult Quality Of Life questionnaire was completed to assess worries, symptoms, and the impact of cardiac surveillance. Results The majority were single (73%), employed or full-time students (93%), with health insurance (94%), had a single left ventricle (78%), the diagnosis of tricuspid atresia or double inlet left ventricle (59%), lateral tunnel Fontan type (44%), history of arrhythmias (76%), left ventricle ejection fraction percentage >50 (66%), oxygen saturations >90% (70%), frequent headaches (50%), scoliosis (22%), varicose veins, ascites, and liver cirrhosis (46%), normal body mass index (59%), and New York Heart Association class I (48%) and II–III (52%). Primary worries related to current health (83%), job/employment (69%), ability to work, (61%) and living independently (54%). The most bothersome symptoms were shortness of breath with ambulation (69%), dizziness (61%), and palpitations (61%). Conclusions Fontan survivors experience residua and sequelae from multiple surgical procedures and the natural disease course. Our results support the need for ongoing assessment of both physical symptoms and psychosocial concerns, and suggest the need for multiple risk factor intervention strategies that improve physical and emotional health in Fontan survivors

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“…Migraines are common in both cyanotic and noncyanotic congenital cardiac lesions, but there are no specific guidelines for their management in adults with CHD [22][23][24][25][26]. The history of headaches (patients 2, 3, and 4) and restless legs syndrome (patient 2) may be unrelated to vertebrobasilar insufficiency, as restless legs syndrome is not a typical manifestation of posterior circulation ischemia and headaches are clearly common in the general population.…”

Section: Commentmentioning

confidence: 93%