Prevalence of methicillin-resistant Staphylococcus aureus in a University Hospital in the South of Brazil

Rodrigues, Mônica de Abreu; Gindri, Lívia; Silva, Aniélen Dutra da; Guex, Camille Gaube; Santos, Silvana Oliveira dos; Hörner, Rosmari

doi:10.1590/s1984-82502015000100004

Cited by 7 publications

(4 citation statements)

References 20 publications

(18 reference statements)

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“…The parameters used in the model are shown in Table 1. 17,28,[32][33][34][35][36][37][38][39][40][41][42][43] The results of the dynamic transmission model for the 2 health outcomes of interest (avoided cases of patients with resistant infection and avoided deaths), for infections caused by any of the 3 microorganisms evaluated, are shown in Appendix Table 5 in Appendix Section 3 in Supplemental Materials found at https://doi. org/10.1016/j.vhri.2021.07.009.…”

Section: Resultsmentioning

confidence: 99%

Cost-Effectiveness of Molecular Method Diagnostic for Rapid Detection of Antibiotic-Resistant Bacteria

Salvador

Lucchetta

Sarti

et al. 2022

Value in Health Regional Issues

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Section: Resultsmentioning

confidence: 99%

Cost-Effectiveness of Molecular Method Diagnostic for Rapid Detection of Antibiotic-Resistant Bacteria

Salvador

Lucchetta

Sarti

et al. 2022

Value in Health Regional Issues

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“…Sabouni, et al, reported the most isolation of MRSA from pediatric intensive care units [19]. A study in Congo showed the prevalence of 63.5% of MRSA among surgical patients hospitalized and Rodrigues, et al, in 2015 reported the medical clinic and adult ICU, had the highest MRSA isolate rates [20,21].…”

Section: Discussionmentioning

confidence: 99%

A Survey of Methicillin-Resistance Staphylococcus aureus Isolated from Patients Hospitalized in the ICU, NICU and Surgical Departments of Tehran University of Medical Sciences Hospitals

Rahimkhani¹

2022

JCIM

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Background and Aim: Staphylococcus aureus is an important pathogen that causes various infections. The presence of some pathogenic factors in this bacterium helps the bacteria to survive in response to the immune system and antimicrobial treatments. Efforts to treat infections caused by these strains have resulted in resistance to most antibiotics, especially methicillin and vancomycin resistance, during recent years. Therefore, the consequences of infections caused by this bacterium can be serious. In this study we aimed to survey methicillin- resistance Staphylococcus aureus isolated from patients hospitalized in the ICU, NICU and surgical departments of Tehran University of Medical Sciences hospitals. Material and Method: 430 clinical samples of the patients were collected and identified as Staphylococcus aureus by phenotype and biotype tests. MRSA isolates were first screened by showing resistance to cefoxitin by disc diffusion method and finally confirmed by examining the mecA gene by PCR. The microbial resistance pattern of MRSA was also measured by disk diffusion method. Investigating the presence of a vancomycin resistance gene in isolated MRSA occurred by PCR. Results: Out of 430 clinical samples, 117 (27.20%) Staphylococcus aureus were isolated of which 42 (35.89%) were identified as MRSA. The most MRSA obtained from the ICU department with 25 cases (59.52%). The majority of patients infected with MRSA belonged to the age group of 40-65 years. The mecA gene was detected in all MRSA. The entire MRSA was 100% sensitive to vancomycin and linezolid, and 100% resistance to cloxacillin. Molecular detection of vanA gene in isolated MRSA showed 2 (4.76%) of them contained vanA gene. Conclusion: The high prevalence of MRSA and its antibiotic resistance pattern to vancomycin and other antibiotic families can lead to treatment failures, uncontrolled nosocomial infections, and mortality. Although the PCR-based detection method is superior to other conventional techniques, a combination of these methods can provide diagnostic accuracy.

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“…No entanto, nos últimos anos, houve uma disseminação dessas cepas que foram adquiridas pela comunidade (CA-MRSA), estando relacionado a pressão seletiva pelo uso inadequado dos antibióticos (Enright et al, 2002;Gelatti et al, 2009a). Em alguns estudos, onde foi realizado o isolamento e caracterização das estirpes, foi evidenciado que há o mesmo gene envolvido tanto da CA-MRSA como na HA-MRSA, tais estirpes são provenientes de setores pediátricos e de hospitais comunitários (Tamariz et al, 2010;Rodrigues et al, 2015).…”

Section: Revisão Bibliográfica E Discussãounclassified

Uma revisão descritiva sobre o perfil de resistência de Staphylococcus spp. em gestantes e uso de extratos de plantas medicinais como perspectiva terapêutica

Mota

Carraro²,

Rey³

et al. 2022

RSD

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Os Staphylococcus spp. têm sido descritos como integrantes rotineiros da microbiota do ser humano em superfície de regiões mais úmidas do corpo, enquanto algumas espécies e subespécies apresentam predileção pela região urogenital. Também são considerados oportunistas e frequentemente tem sido causa de infeção em pacientes com comprometimento do sistema imunológico ou em uso de dispositivos invasivos em pacientes hospitalizados. No entanto, nos últimos anos, houve uma disseminação dessas cepas pela comunidade, o que possivelmente pode estar relacionado a pressão seletiva pelo uso inadequado dos antibióticos. As infecções causadas por Staphylococcus spp. meticilina resistente tem causado sérios problemas dentro e fora do ambiente hospitalar. Dentro da comunidade causa colonização de pessoas aumentando a chance de óbito em todos os sexos e faixa etária e em gestantes têm sido consideradas importantes fontes de microrganismos patógenos pelos fatores de virulência apresentados por essa bactéria e pelas condições fisiológicas e anatômicas da gestante, tornando-se, dessa forma, uma ameaça de propagação de infecções por cepas multirresistentes.

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Prevalence of methicillin-resistant Staphylococcus aureus in a University Hospital in the South of Brazil

Cited by 7 publications

References 20 publications

Cost-Effectiveness of Molecular Method Diagnostic for Rapid Detection of Antibiotic-Resistant Bacteria

Cost-Effectiveness of Molecular Method Diagnostic for Rapid Detection of Antibiotic-Resistant Bacteria

A Survey of Methicillin-Resistance Staphylococcus aureus Isolated from Patients Hospitalized in the ICU, NICU and Surgical Departments of Tehran University of Medical Sciences Hospitals

Uma revisão descritiva sobre o perfil de resistência de Staphylococcus spp. em gestantes e uso de extratos de plantas medicinais como perspectiva terapêutica

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