Prevalence of lower urinary tract infection in South Indian type 2 diabetic subjects

J, Janifer Jasmine; Geethalakshmi, S; Satyavani, K; Viswanathan, V

doi:10.4103/0971-4065.65315

Cited by 23 publications

(26 citation statements)

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“…16 [15], they differ from several others, such as the investigation by Citron et al [6], which revealed 2.7 IPC among aerobic and 2.3 IPC among anaerobic bacteria in a diabetic population involving 433 patients with foot infections.…”

Section: Discussionmentioning

confidence: 60%

Increasing incidence of Gram-negative organisms in bacterial agents isolated from diabetic foot ulcers

Turhan

Mutluoğlu

Acar

et al. 2013

J Infect Dev Ctries

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Section: Discussionmentioning

confidence: 60%

Increasing incidence of Gram-negative organisms in bacterial agents isolated from diabetic foot ulcers

Turhan

Mutluoğlu

Acar

et al. 2013

J Infect Dev Ctries

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“…17,18 The differences in the study region, age group, study settings might be the reason for differences in the prevalence of pathogens. In our study Staphylococcus aureus which was methicillin resistant was the most common grampositive isolate followed by Pseudomonas aeruginosa among gram negative.…”

Section: Resultsmentioning

confidence: 99%

Bacteriological study of diabetic foot ulcer according to Wagner’s classification: a one-year study

Malepati

Vakamudi

Kandati³

et al. 2017

Int Surg J

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Background: Diabetes is considered as one of the most important and rapidly evolving non-communicable disease which requires top priority around the world. 10-25% of diabetics develop foot infections [DFI’s] during the course of their disease period ranging from simple calluses to major Osteomyelitis. 3 Microbial infections of the diabetic foot ulcers are difficult to manage because of multiple factors associated in response including overall glycaemic control, associated complications like vascular disease and neuropathy. The present study was done to assess the microbial flora according to Wagner’s classification for diabetic foot disease. To isolate, identify the aerobic bacterial pathogens and their drug sensitivity pattern with reference to ESBL productionMethods: A prospective study was conducted at a tertiary care hospital by department of general surgery among Diabetics presenting with diabetic foot infections. All the enrolled cases were classified based on Wagner’s classification and socio demographic data was noted. Specimens from the ulcer were collected and processed for isolation, identification of pathogens based on standard CLSI guidelines. The antibiotic sensitivity of the isolates was done and ESBL production was demonstrated by standard guidelines.Results: 346 cases were enrolled in study and grade-3 Wagner’s ulcers were predominant. Males were predominant, 46-55 years age group was common with mean age of 55.3±1.4 years. Peripheral arterial disease was more common than peripheral neuropathy and both were found significantly associated with development of ulcers. Methicillin resistant Staphylococcus aureus and Pseudomonas aeruginosa were most common isolates. MRSA exhibited maximum sensitivity to vancomycin, clindamycin and linezolid. Gram negative isolates exhibited maximum sensitivity to meropenems, piperacillin-tazobactam. The prevalence of ESBL producers in the study was 16.24%.Conclusions: DFI are a serious concern in uncontrolled diabetics and require proper management. Outcome of the infection depends upon the grading of the ulcer as per Wagner’s classification and also the nature of the infection either polymicrobial or with a single organism. Our study highlights and suggests that prospective multicentre studies are required to assess the appropriate antibiotic regimen in diabetic foot ulcers and proper management of antibiotics must be implemented to decrease the incidence and development of multi drug resistant organisms.

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“…In a study, the prevalence of pathogens in diabetic foot infections in relation to parameters such as Wagner's grading, duration of diabetes, and healing times was studied [119]. It was found that in 654 diabetic patients, 728 pathogens were isolated.…”

Section: Epidemiology Of Infection In Diabetic Foot Patientsmentioning

confidence: 99%

Diabetic Foot Ulcer: A Review

Zubair¹

2015

AJIM

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Diabetic foot problems are common throughout the world, resulting in major medical, social and economic consequences for the patients, their families, and society. Foot ulcers are more likely to be of neuropathic origin, and therefore eminently preventable. People at greatest risk of ulceration can easily be identified by careful clinical examination of the feet: education and frequent follow-up. Infection when complicates a foot ulcer, combination can be limb or life-threatening, and infection is defined clinically, but wound cultures assist in identifying the causative pathogens. Tissue specimens are strongly preferred to wound swabs for wound cultures. Antimicrobial therapy should be guided by culture results, and although such therapy may cure the infection, it does not heal the wound. Alleviation of the mechanical load on ulcers (offloading) should always be a part of treatment. Plantar neuropathic ulcers typically heal in 6 weeks with irremovable casting, because pressure at the ulcer site is mitigated and compliance is enforced. The success of other approaches to offloading similarly depends on the patients' adherence to the effectiveness of pressure relief.

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Prevalence of lower urinary tract infection in South Indian type 2 diabetic subjects

Cited by 23 publications

References 0 publications

Increasing incidence of Gram-negative organisms in bacterial agents isolated from diabetic foot ulcers

Increasing incidence of Gram-negative organisms in bacterial agents isolated from diabetic foot ulcers

Bacteriological study of diabetic foot ulcer according to Wagner’s classification: a one-year study

Diabetic Foot Ulcer: A Review

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