Prevalence of idiopathic intracranial hypertension and associated factors in obese children and adolescents

Tepe, Derya; Demirel, Fatma; Şeker, Esra Dağ; Arhan, Ebru; Tayfun, Meltem; Esen, İhsan; Kara, Özlem; Kızılgün, Murat

doi:10.1515/jpem-2015-0470

Cited by 9 publications

(12 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our study population, the percentage of subjects with an abnormal carbohydrate metabolism is (of unknown reasons) lower compared to, e.g., that of the Swedish childhood obesity treatment registry BORIS showing a prevalence of 17.1% [5]. In contrast to other studies, the prevalence of hypertension in our study population is high [23,24]. This can be explained by the high percentage of obese and extremely obese patients, and the use of KiGGS reference values for definition of hypertension [25].…”

Section: Discussioncontrasting

confidence: 59%

Changing Characteristics of Obese Children and Adolescents Entering Pediatric Lifestyle Intervention Programs in Germany over the Last 11 Years: An Adiposity Patients Registry Multicenter Analysis of 65,453 Children and Adolescents

Bohn

Wiegand²,

Kieß³

et al. 2017

Obes Facts

View full text Add to dashboard Cite

Objective: To examine whether characteristics of children and adolescents who start lifestyle intervention (LI) for obesity in Germany changed over the last decade. Methods: 65,453 subjects (<21 years) from the APV database (Adiposity Patients Registry) with a BMI ≥ 90th percentile were included (years 2005-2015). Logistic regression models (confounders: age, sex, migration background) were created for overweight, obesity, extreme obesity, and obesity-related comorbidities. Comorbidities were further adjusted for weight category. Results were stratified by inpatient or outpatient care. Results: Extreme obesity was found to be more frequent at the onset of LI (2005: 11.6; 2015: 12.7%) with a similar trend in subgroups (p < 0.001). Obesity increased (2005: 50.3%; 2015: 55.1%), and overweight decreased (2005: 34.1%; 2015: 29.0%) in the whole study population. Trends were similar for inpatient or outpatient care (all p < 0.001). Hypertension increased from 45.7% to 49.2% in the whole study population, and similar data were obtained in the subgroup of inpatients (both p < 0.0001). Dyslipidemia increased in all patients (2005: 21.9%; 2015: 28.0%) and in inpatients (2005: 20.2%; 2015: 25.7%; both p < 0.0001). Abnormal carbohydrate metabolism rose in all patients (from 5.2 to 6.4%; p = 0.0002) without significant trends in subgroups. Conclusion: During the last decade, children and adolescents presented with higher BMI SDS at the onset of LI and the proportion with obesity-related comorbidities increased. Particularly the presence of comorbidities differed between outpatients and inpatients.

show abstract

Section: Discussioncontrasting

confidence: 59%

Changing Characteristics of Obese Children and Adolescents Entering Pediatric Lifestyle Intervention Programs in Germany over the Last 11 Years: An Adiposity Patients Registry Multicenter Analysis of 65,453 Children and Adolescents

Bohn

Wiegand²,

Kieß³

et al. 2017

Obes Facts

View full text Add to dashboard Cite

show abstract

“…Moreover, complaints of headache, blurred vision and vomiting were significantly higher in subjects with IIH compared to other subjects. In this study, insulin resistance, dyslipidemia and hepatosteatosis were found to be more prevalent with IIH than the others [11]. Our patient's abnormal blood tests that could suggest a developing metabolic syndrome, with TGO and TGP levels higher than normal, hypertension, but lipid-line investigation did not identify dyslipidemia.…”

Section: A B Discussioncontrasting

confidence: 43%

Idiopathic intracranial hypertension in child

Zemba¹,

Dimirache²,

Rogoz³

2020

rjo

View full text Add to dashboard Cite

We present the case of a 12-year-old boy with bilateral papilledema, relating moderate symptomatology and without an important medical history. Ophthalmological examination revealed a significant alteration of visual acuity, an important papilledema and macular edema in both eyes. Further investigations excluded infectious and autoimmune diseases, intracranial masses and congenital affliction. Because of an elevated opening pressure in lumbar puncture procedure, the diagnosis of intracranial hypertension was confirmed. After two weeks of treatment with corticosteroids, carbonic anhydrase inhibitor and hyperosmotic drug, the patient had an important structural and functional ophthalmological improvement.

show abstract

“…In contrast, a study of obese children and adolescents found that those identified with pseudotumor cerebri syndrome (1.32%) had significantly higher morning cortisol levels. 30 Hormonal changes in children with pseudotumor cerebri syndrome are grossly understudied, and investigation into whether these hormonal changes can trigger headache or even venous sinus stenosis would be particularly interesting.…”

Section: Discussionmentioning

confidence: 99%

Assessment of Pediatric Pseudotumor Cerebri Clinical Characteristics and Outcomes

et al. 2020

View full text Add to dashboard Cite

Pseudotumor cerebri also known as idiopathic intracranial hypertension is a relatively uncommon disorder of unknown pathophysiology. Although pseudotumor cerebri occurs in both children and adults, the pseudotumor cerebri literature is heavily dominated by adult studies. The aim of this study is to retrospectively describe the clinical presentation, imaging, treatment, and outcomes of a large pediatric pseudotumor cerebri population over a 23-year period. We also discuss secondary pseudotumor cerebri (44%) as well as the increasingly recognized patient subgroups without headache (13.3%) and without papilledema (7.3%). Female sex, obesity, and initial symptoms were consistent with the literature; however radiographic findings were surprisingly low in this cohort. Headache outcomes at 1 week, 1 month, and 3 months following initial lumbar puncture/treatment and visual function outcomes are reported.

show abstract

Prevalence of idiopathic intracranial hypertension and associated factors in obese children and adolescents

Abstract: In childhood obesity, IIH should be kept in mind as a serious complication. Funduscopic examination is an easy method that suggests IIH. In particular, obese children with systemic hypertension and refractory headache should be considered for IIH.

Cited by 9 publications

References 42 publications

Changing Characteristics of Obese Children and Adolescents Entering Pediatric Lifestyle Intervention Programs in Germany over the Last 11 Years: An Adiposity Patients Registry Multicenter Analysis of 65,453 Children and Adolescents

Changing Characteristics of Obese Children and Adolescents Entering Pediatric Lifestyle Intervention Programs in Germany over the Last 11 Years: An Adiposity Patients Registry Multicenter Analysis of 65,453 Children and Adolescents

Idiopathic intracranial hypertension in child

Assessment of Pediatric Pseudotumor Cerebri Clinical Characteristics and Outcomes

Contact Info

Product

Resources

About