Prevalence of Hypovitaminosis D in Patients Visiting a Tertiary Care Center in Chitwan, Nepal

Bhattarai, Kushal; Manandhar, Nilu; Dhakal, Sarita

doi:10.3126/jcmsn.v15i2.23483

Cited by 6 publications

(11 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Almost all CBPM studies (94.44%) were low risk in all domains of applicability. Eight [ 20 , 31 , 38 , 39 , 44 , 50 , 52 , 57 ] (16.7%) and 7 (12.9%) studies [ 30 , 34 , 41 , 46 , 49 , 55 , 58 ] were high or unclear bias in selection of study subjects, accordingly. Fifty-two studies (96.3%) [ 9 , 11 , 19 – 31 , 33 – 38 , 40 – 66 , 70 , 71 , 74 ] applied the index/study test before the reference standard but with unclear explanation of blinding.…”

Section: Resultsmentioning

confidence: 99%

“…Among 54 CBPM studies, 31 studies [ 9 , 11 , 19 – 34 , 40 , 58 – 66 , 71 – 73 ] reported 2 × 2 table data which could be assessed for diagnostic performance, while 7 [ 35 – 39 , 41 , 42 ] and 16 [ 43 – 57 , 70 ] studies reported data for only positive and negative CBPM respectively (see Table 1 ). The mean age ranged from 28 to 62 years and percent male ranged from 35 to 100%.…”

Section: Resultsmentioning

confidence: 99%

“…Among the studies that reported 2 × 2 data (n = 66,767), 29 studies [ 9 , 11 , 20 – 34 , 40 , 58 – 63 , 66 , 72 – 74 ] used a CBPM cutoff threshold as ≥ 140/90 for diagnosis of HT, while one study [ 19 ] used the threshold of DBP > 95 mmHg and one study did not reported the threshold. The 24-h ABPM had a cut-off of ≥ 130/80 mmHg for 12 studies [ 11 , 26 , 31 – 33 , 58 , 59 , 61 – 63 , 74 ] and daytime ABPM had a cut-off of ≥ 135/85 mmHg for 16 studies [ 20 – 25 , 28 – 30 , 34 , 60 , 65 , 66 , 73 ]. Two [ 27 , 72 ] and one [ 19 ] studies applied daytime ABPM with cut-offs of ≥ 140/85 and DBP ≥ 95 mmHg, respectively (see Additional file 1 : Table 2).…”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Diagnostic performance of clinic and home blood pressure measurements compared with ambulatory blood pressure: a systematic review and meta-analysis

Karnjanapiboonwong

Anothaisintawee

Chaikledkaew

et al. 2020

BMC Cardiovasc Disord

View full text Add to dashboard Cite

Background Clinic blood pressure measurement (CBPM) is currently the most commonly used form of screening for hypertension, however it might have a problem detecting white coat hypertension (WCHT) and masked hypertension (MHT). Home blood pressure measurement (HBPM) may be an alternative, but its diagnostic performance is inconclusive relative to CBPM. Therefore, this systematic review aimed to estimate the performance of CBPM and HBPM compared with ambulatory blood pressure measurement(ABPM) and to pool prevalence of WCHT and MHT. Methods Medline, Scopus, Cochrane Central Register of Controlled Trials and WHO's International Clinical Trials Registry Platform databases were searched up to 23rd January 2020. Studies having diagnostic tests as CBPM or HBPM with reference standard as ABPM, reporting sensitivity and specificity of both tests and/or proportion of WCHT or MHT were eligible. Diagnostic performance of CBPM and HBPM were pooled using bivariate mixed-effect regression model. Random effect model was applied to pool prevalence of WCHT and MHT. Results Fifty-eight studies were eligible. Pooled sensitivity, specificity, and diagnostic odds ratio (DOR) of CBPM, when using 24-h ABPM as the reference standard, were 74% (95% CI: 65–82%), 79% (95% CI: 69%, 87%), and 11.11 (95% CI: 6.82, 14.20), respectively. Pooled prevalence of WCHT and MHT were 0.24 (95% CI 0.19, 0.29) and 0.29 (95% CI 0.20, 0.38). Pooled sensitivity, specificity, and DOR of HBPM were 71% (95% CI 61%, 80%), 82% (95% CI 77%, 87%), and 11.60 (95% CI 8.98, 15.13), respectively. Conclusions Diagnostic performances of HBPM were slightly higher than CBPM. However, the prevalence of MHT was high in negative CBPM and some persons with normal HBPM had elevated BP from 24-h ABPM. Therefore, ABPM is still necessary for confirming the diagnosis of HT.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Diagnostic performance of clinic and home blood pressure measurements compared with ambulatory blood pressure: a systematic review and meta-analysis

Karnjanapiboonwong

Anothaisintawee

Chaikledkaew

et al. 2020

BMC Cardiovasc Disord

View full text Add to dashboard Cite

show abstract

“…Among them, they had 57.7% hypovitaminosis D, 35.3% normovitaminosis D and 7.0% hypervitaminosis D. Among the hypovitaminosis D, 14.9% of the total participants had deficient and 42.8% of the total participants had insufficient vitamin D status. Bhattarai et al in their study found 34.8% deficient, 35.9% insufficient, 28.7% normal and 0.6% hypervitaminosis D (Bhattarai et al, 2019). Sadiya et al had also conducted similar study in Bangladesh and found 14.1% deficient, 34.7% insufficient and 51.2% normal level of vitamin D (Sadiya et al, 2021).…”

Section: Discussionmentioning

confidence: 88%

“…This 'sun-shine' vitamin synthesis begins in the skin on exposure with ultraviolet rays with further reactions takes place in the liver and the kidneys (Bhattarai et al, 2019). Vitamin D is derived from 7-dehyrocholesterol which then converts to cholecalciferol due to ultraviolet radiation from the sunlight in the skin.…”

Section: Research Articlementioning

confidence: 99%

Status of Vitamin D among Patients Visiting a Tertiary Care Centre in Rupandehi, Nepal

Shah¹,

Sinha

Jha

et al. 2021

Int J Appl Sci Biotechnol

View full text Add to dashboard Cite

Serum vitamin D is one of the fat-soluble vitamin which has the role in maintenance of calcium and phosphorus levels and ultimately proper bone health and various physiological processes. Although many studies prevail hypovitaminosis D, we focused to find out the pattern of elevated or decreased serum vitamin D level as its deficiency and surplus have adverse effects to our health.. For this, a retrospective study was done from the records present in a hospital laboratory of Devdaha Medical College and Research Institute (DMCRI), Rupandehi, Nepal from January 2018 to December 2020 where 201 participants with 70.1% male and 29.9% female with different age groups were present. From total participants, 14.9% had deficient, 42.8% had insufficient, 35.3% had sufficient and 7% had high level of serum vitamin D. Male had 2.9% deficient and 14,9% insufficient vitamin D whereas female had 11.9% deficient, 27.8% insufficient and 7.0% surplus vitamin D. The greater prevalence of hypovitaminosis D in the females than the males could be overcome by the necessary strategies in the form of further studies and judicious supplementation vitamin D in the target population by monitoring the level of serum vitamin D. Int. J. Appl. Sci. Biotechnol. Vol 9(4): 256-260.

show abstract

Epidemiology and determinants of vitamin D deficiency in Eastern Nepal: a community-based, cross-sectional study

Sherchand

Baranwal

Gelal

2022

Preprint

View full text Add to dashboard Cite

ObjectiveTo estimate the prevalence of vitamin D deficiency in Eastern part of Nepal and identify the sociodemographic factors associated with it.MethodsA descriptive cross-sectional study was carried out among 324 participants between the ages of 18 to 80 years from Sunsari and Morang districts of Nepal. A semi-structured questionnaire was administered to obtain sociodemographic variables followed by anthropometric measurements and blood sampling. 25(OH)D level was measured by Chemiluminescence immunoassay (CLIA) technique via a fully automated Maglumi 1000 analyzer (SNIBE Co, Ltd, China). Serum 25(OH)D was classified as deficient, insufficient and sufficient (<20 ng/ml, 20-29 ng/ml and 30–100 ng/ml respectively). Chi square test was used to analyze the sociodemographic variables. Significant variables were subject to multivariate logistic regression.Result181(55.9%) of the study population had vitamin D deficiency. There was significant association between vitamin D status and gender (Chi-sq = 6.2, p=0.04), education (Chi-sq = 14.4, p=0.02), skin colour (Chi-sq = 17.9, p=0.001), sun exposure (Chi-sq = 11.1, p=0.02), duration of sun exposure (Chi-sq = 15.1, p=0.004), type of meat intake (Fischer’s exact test is 16.4, p=0.01), frequency of fish intake (Fischer’s exact test is 19.3, p=0.001), frequency of dairy intake (Chi-sq=11.2, p=0.02). In multivariate regression, OR (95% CI) for vitamin D deficiency was significantly higher in women than men [3.0(1.3-7.0) p:0.008], education level up to primary school had lower OR(95% CI) [0.1(0.03-0.4) p:0.001] than higher education. Consumption of dairy products ≥3/week had lower OR(95% CI) [0.1(0.06-0.5) p:0.003.] Weekly fish consumption had lower OR(95% CI) [0.04(0.004-0.4) p: 0.007].ConclusionThe prevalence of vitamin D deficiency was high in women of eastern Nepal.

show abstract

Prevalence of Hypovitaminosis D in Patients Visiting a Tertiary Care Center in Chitwan, Nepal

Cited by 6 publications

References 29 publications

Diagnostic performance of clinic and home blood pressure measurements compared with ambulatory blood pressure: a systematic review and meta-analysis

Diagnostic performance of clinic and home blood pressure measurements compared with ambulatory blood pressure: a systematic review and meta-analysis

Status of Vitamin D among Patients Visiting a Tertiary Care Centre in Rupandehi, Nepal

Epidemiology and determinants of vitamin D deficiency in Eastern Nepal: a community-based, cross-sectional study

Contact Info

Product

Resources

About