Prevalence of hypothyroidism in patients with biliary stones: a prospective study

Singh, Rana Ranjit; Gupta, Arun Kumar; Shah, Sukrit; Shah, Amip; Singh, Kulwant; Bhatia, A

doi:10.18203/2349-2902.isj20162838

Cited by 4 publications

(5 citation statements)

References 5 publications

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“…13 An observational study by Singh et al in Punjab during 2014-2016 to understand the prevalence of hypothyroidism in cholelithiasis showed a similar gender distribution to the current study and concluded that there is no significant relation between thyroid status and biliary calculi. 15 In the showed no association between hypothyroidism and gallstones. 17 Incidence of hypothyroidism noted in Watali et al study was high in patients aged above 50 years, which goes along with this current study.…”

Section: Discussionmentioning

confidence: 90%

Prevalence of undiagnosed hypothyroidism in patients with gall bladder stones in Belagavi

Koujalagi¹,

Karagi²,

Gogate³

et al. 2021

Int Surg J

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Background: Contribution of hypothyroidism to gallstone formation is debated over years. With this background, the study intended to analyze the prevalence of undiagnosed hypothyroidism in patients with cholelithiasis. The aim is to understand the prevalence of hypothyroidism in patients with gallstones.Methods: A prospective, hospital-based study was done on 100 patients admitted for the management of gall stone disease in Belagavi. After initial screening, a detailed history was obtained with special reference to symptomatology and the risk factors as per proforma from patients meeting selection criteria. Thyroid function test was done on all eligible patients. Patients were divided into three groups of Euthyroid, Subclinical hypothyroid and clinical hypothyroidism. Statistical analysis used. Percentage of gall stones in different age groups and gender of the study population was calculated followed by prevalence of hypothyroidism and subclinical hypothyroidism in all the patients included.Results: Among the study population, 40% were male and 60% were female. 23 of them have subclinical hypothyroidism and 6 of them were diagnosed with hypothyroidism. Majority of subclinical hypothyroid patients (39.13%) were aged 41-60 years. Hypothyroid symptoms were shown by the study population with unknown thyroid status.Conclusions: The prevalence of hypothyroidism in cholelithiasis is 29% in the study and is significant. The study demands further studies to consider hypothyroidism as a cause /risk factor for biliary calculus.

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Section: Discussionmentioning

confidence: 90%

Prevalence of undiagnosed hypothyroidism in patients with gall bladder stones in Belagavi

Koujalagi¹,

Karagi²,

Gogate³

et al. 2021

Int Surg J

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“…Singh RR conducted a study to assess the relation of thyroid disorders and gall bladder stones in male patients. [24] They recorded 24% patients were suffering with hypothyroid disease and 12% patients were suffering from hyperthyroid disorder.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Thyroid Disorders in Patients of Gall Bladder Stones: A Prospective Study

Singh¹,

Kaul²,

Singh³

et al. 2018

AIMDR

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Background: Gall bladder stones are one of the commonest abdominal disorder requiring hospitalization and surgery in India. In Europian countries more than 10% prevalence of gall bladder stone has been recorded. Different studies suggested that sluggish movement of bile during hypothyroidism may induce formation of stone in gall bladder. Moreover, use of thyroxine for dissolving gall bladder stone has been suggested in studies. However, relation of thyroid hormones and gall bladder stone is still unclear. Therefore, present study was designed to assess if there is any relation between thyroid hormones disorders and gall bladder stones. Methods: It was cross sectional type of study which was conducted in departments of general surgery of TMMC & RC, Moradabad. This study was carried out from April 2017 to December 2017. Study population included 100 patients of cholelithiasis undergoing for cholecystectomy. Surgical profile along with full history including name, age, sex etc was recorded in the study. Similarly, full history of control group subjects was taken. Thyroid hormones in serum total tri iodothyronine (T3), free thyroxine (FT4), and TSH were measured by Enzyme Linked Immunosorbent Assay (ELISA) method. Results: Gall bladder stone were more common in female patients (60) in comparison of male patients (40). Hypothyroid disorder was found in 20% male gall bladder patients. Whereas, 7.5% hyperthyroid disease in male cholelethiais patients. Euthyroid status was observed in 72.5% male gall bladder patients. Hypothyroid disorder was found in 14% female gall bladder patients. Whereas, 7% hyperthyroid disease in female cholelethiais patients. Euthyroid status was observed in 65% female gall bladder patients. Conclusion: Findings of the current study suggest that female population suffers more in comparison of male population. Further, prevalence of gall bladder stones were more in 51 to 60 years age group population. Further, no definite relation was observed between thyroid hormones disorders either hypothyroid or hyperthyroid and gall bladder stones. However, more studies of on larger populations are required to assess if there is any relation between thyroid disorders and gall bladder stones.

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“…According to Singh et.al an advanced age, high BMI and serum lipids were identified as major independent risk factors for cholelithiasis 14 . However in our study only 6% gallstone disease subjects were obese.…”

Section: Discussionmentioning

confidence: 99%

The prevalence of hypothyroidism in diagnosed cases of cholelithiasis

2020

IJCBR

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Introduction:The aim of this study was to evaluate the prevalence of hypothyroidism in diagnosed cases of cholelithiasis using the patient's ultrasonography data and to find the prevalence of obesity in gallstone disease. Materials and Methods: This study was conducted in Govt. medical college, Thrissur. Two hundred and sixty five study subjects were selected from the patients who were attending wards and outpatient department (OPD) of General Surgery with diagnosed cases of cholelithiasis by ultrasound of abdomen. All the participants were subjected to clinical examination and lab investigations. Serum thyroid-stimulating hormone (TSH) was used to assess thyroid function and thereby hypothyroidism. Body Mass Index (BMI) was used to assess obesity. Results: High prevalence of hypothyroidism (23%) was observed in gallstone disease. In this study only 6% gallstone disease subjects were obese. We also found that 73% of the study subjects with hypothyroidism were obese. Conclusion: Hypothyroidism may be suggested as a risk factor for developing gallstone disease. Gallstone patients should be checked for serum TSH because of high incidence of hypothyroidism.

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Prevalence of hypothyroidism in patients with biliary stones: a prospective study

Cited by 4 publications

References 5 publications

Prevalence of undiagnosed hypothyroidism in patients with gall bladder stones in Belagavi

Prevalence of undiagnosed hypothyroidism in patients with gall bladder stones in Belagavi

Prevalence of Thyroid Disorders in Patients of Gall Bladder Stones: A Prospective Study

The prevalence of hypothyroidism in diagnosed cases of cholelithiasis

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