Prevalence of Helicobacter pylori Infection in Patients with Dyspeptic Symptoms in Damaturu Metropolitan

Abstract

Aim: To study the prevalence of Helicobacter pylori (H. pylori) contamination among dyspeptic patients in Damaturu and report on the relationship between H. pylori predominance and different age groups in the population under study.
 Methods: A sum of 229 volunteers with dyspeptic symptoms (140 females and 89 males; mean period of 43.6 ± 14.2 years) took an interest in the investigation. The status of infection caused by H. pylori was determined using serological test. Information was gathered by the utilization of self-managed survey while status of H. pylori was resolved dependent on the serological examination (fast symptomatic test). The one Step H. Pylori serum whole blood rapid test kit was used to detect the presence of IgG antibodies specific to H. pylori infections in the participants.
 Results: The prevalence of H. pylori disease was 51.96%. There was no noteworthy factual relationship between age and contamination rate at p-value (0.1515). In young subjects (under 11 years of age), the H. pylori contamination rate was moderately higher (50.00%). The most extreme number of the positive patients was found in the age range of 50-59 years (69.23%) and the base prevalence was in the age range of 10-19 years (50.00%).
 The overall prevalence of H. pylori contamination between the gender is out of 89 males, 55 were found to be positive to the infection (61.79%), while out of 140 females, 64 were also positive (45.71%). Despite these findings, there was no critical factual relationship between the genders and H. pylori infection (p=0.113). The statistical qualities of members at the examination section demonstrate that out of 129 patients having a place with the upper lower class, 85 subjects (66.40%) were found to be positive to H. pylori. The lower-middle-class demonstrates that out of 89 subjects 30 were positive (33.70%), while upper-middle outcome demonstrates that out of 12 subjects 4 were confirmed with 33.33%. This demonstrates that subjects living under overcrowded conditions with dense population have a high contamination rate of H. pylori and therefore is a noteworthy factual relationship between socio-statistic factors and overall prevalence of H. Pylori infection (p = 0.001).
 Conclusion: We came to realize the overall prevalence of H. pylori contamination in patients with dyspeptic symptoms in Damaturu. The H. pylori contamination might be a hazard factor for peptic ulcer and more grounded gastritis.

Helicobacter pylori Seromarkers in a University Students Population in Central Nigeria

“…Before then, laboratory analysis of upper gastrointestinal diseases that shows dyspepsia was with much complexity [3]. However, H. pylori has become a key etiological factor considered in cases of peptic ulcer disease (PUD), chronic gastritis, gastric cancer, and gastric mucosa associated lymphoid tissue (MALT) lymphoma in recent times [4][5][6][7].…”

“…But in most situations, infected individuals are shows associated symptoms like mild to severe scorching intestinal ache that outspreads from the navel to the chest region. Nausea, loss of appetite, weight loss, vomiting, indigestion, and melena are other symptoms of this infection [5,6,9]. This bacterial pathogen is the primary cause of ulcers and its exact route of spread is still not known [4], there are other factors that has impact in ulcer generation including use of non-steroidal anti-inflammatory drugs (NSAIDs) like; ibuprofen, aspirin and piroxican [11].…”

“…However, fecal antigen and urea breath tests shows utmost precision to check and approve the pathogen [13]. Nevertheless, serologic assays that detect the antibodies of H. pylori presence in human serum is commonly used especially in low resource countries like Nigeria [6,14]. Practicing good hygiene and hand washing, especially with food preparation are keys for prevention of H. pylori infection while treatment is best by combination of antibiotics and proton pump inhibitors [4,15].…”

“…In developing countries the bacterial infection is high when compared to developed nations, maybe because of lack of basic social amenities, poor sanitary conditions, low socio-economic status, and reduced use of antibiotics for dissimilar pathologies [10,[16][17][18]. The prevalence rate of the infection ranges from 30-40 percent in the United States and parts of Europe [19][20], 80-90 percent in South America and 70-90 percent in Africa continent [6,15,16]. In a hyper-endemic area of this bacterial infection like Nigeria [6,7,21,22], there is a serious need to update the knowledge on the epidemiology of this bacterial infection and its related predictors to generate intervention programs that will reduce the morbidity and mortality of infected individuals.…”

“…The prevalence rate of the infection ranges from 30-40 percent in the United States and parts of Europe [19][20], 80-90 percent in South America and 70-90 percent in Africa continent [6,15,16]. In a hyper-endemic area of this bacterial infection like Nigeria [6,7,21,22], there is a serious need to update the knowledge on the epidemiology of this bacterial infection and its related predictors to generate intervention programs that will reduce the morbidity and mortality of infected individuals. Therefore, this chapter principally determined the seromarkers for H. pylori infection among students of Nasarawa State University Keffi, Central Nigeria.…”