Prevalence of Glaucoma in a Rural Northern China Adult Population

Song, Wulian; Li, Shan; Cheng, Fang; Fan, Pan; Zhang, Lijuan; Qu, Wei; Zhang, Qiuju; Yuan, Huiping

doi:10.1016/j.ophtha.2011.02.050

Cited by 93 publications

(29 citation statements)

References 25 publications

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“…An increasing Trends of glaucoma drug prescriptions number of patients with glaucoma was also revealed in another study [3]. Although glaucoma can occur at any age, aging is a major risk factor [11][12]. The prolonged life expectancy of the Chinese population and a rapidly aging society result in an increased number of elderly individuals with a high risk of glaucoma [13].…”

Section: Discussionmentioning

confidence: 72%

Prescribing trends of glaucoma drugs in six major cities of China from 2013 to 2017

Ding

Luo

et al. 2020

PLoS ONE

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ObjectiveTo evaluate the prescribing trends of glaucoma drugs in six major cities of China from 2013 to 2017. MethodsA descriptive analysis using pharmacy prescription data was conducted. Outpatient prescription data was extracted from the Hospital Prescription Analysis Cooperative Project. Prescribing patterns, trends of visits, and corresponding expenditures for glaucoma medications were analyzed. ResultsA total of 84297 ambulatory prescriptions were included in the current study. Visits by glaucoma patients increased from 13808 in 2013 to 20060 in 2017. Over the same period, the yearly expenditure for glaucoma drugs increased from 2.33 million to 3.95 million Chinese Yuan (CNY). Among all the six classes of glaucoma drugs (prostaglandin analogues, carbonic anhydrase inhibitors, α-receptor agonists, β-receptor antagonists, cholinergic agonists and fixed combinations), β-receptor antagonists were the most commonly prescribed in 2013, accounting for 34.3% of patients, but gradually decreased to 27.1% in 2017. Prostaglandin analogues became the most frequently prescribed drugs in 2017, accounting for 30.2% of the visits. Prostaglandin analogues are the most expensive and yielded a total expenditure of 2.34 million CNY in 2017, followed by carbonic anhydrase inhibitors, α-receptor agonists, β-receptor antagonists, fixed combinations, and cholinergic agonists. Combination therapy became increasingly prescribed in 2017. ConclusionGlaucoma prescribing practices exhibited substantial changes over the study period. The number of glaucoma prescriptions continuously increased from 2013 to 2017, leading to increased prescription costs. These findings implied a similar trend observed in previous studies, as well as recommendations in the appropriate guidelines.

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Section: Discussionmentioning

confidence: 72%

Prescribing trends of glaucoma drugs in six major cities of China from 2013 to 2017

Ding

Luo

et al. 2020

PLoS ONE

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“…Using the digital remote screening model, general eye examinations such as IOP testing and retinal photography were performed. POAG suspects were followed up and diagnosed by Shanghai Eye Disease Prevention and Treatment Center based on the ISGEO criteria used worldwide [ 4 – 10 ].…”

Section: Discussionmentioning

confidence: 99%

“…Population-based screening for POAG has been carried out in some regions of China, including four locations in the north (Inner Mongolia [ 4 ], Beijing [ 5 ], Handan [ 6 ], and Harbin [ 7 ]), one in the south (Guangzhou [ 8 ]), and one in the southwest (Yunnan [ 9 ]). In the east of China, especially in Shanghai with a higher percentage of aging population, however, no screening has been performed.…”

Section: Introductionmentioning

confidence: 99%

Prevalence and risk factors of primary open-angle glaucoma in a city of Eastern China: a population-based study in Pudong New District, Shanghai

Zou

Lee³

et al. 2015

BMC Ophthalmol

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BackgroundThe aim of the present study was to investigate the prevalence and characteristics of primary open-angle glaucoma among the urban population of Pudong New District, Shanghai.MethodsThree residents’ committees were randomly selected from Pudong New District, and residents aged 50 and older were screened for primary open-angle glaucoma (POAG) from March to April 2011. In remote screening, the tests on visual acuity, refraction, intraocular pressure (IOP), and the photographs of anterior segment and fundus were used to identify POAG suspect. The suspected subjects were then reexamined with the tests on IOP, gonioscopy, Humphrey visual field test, and retinal nerve fiber layer (RNFL) thickness by optical coherence tomography (OCT). POAG was diagnosed according to the criteria defined by International Society for Geographic and Epidemiological Ophthalmology (ISGEO). Finally, POAG risk factors were evaluated using logistic regression analysis.ResultsA total of 2528 citizens out of 3,146 eligible residents (80.36 %) participated in this study. Among the citizens, 72 were diagnosed to have POAG, giving the crude prevalence rate of 2.85 % (95 % CI:2.20 %–3.50 %) in general and age- and gender-adjusted prevalence rate of 2.8 % (95 % CI: 2.78 %–2.83 %). Among the 72 POAG patients, only 22 cases had IOP exceeding 21 mmHg while other 50 cases had IOP of 21 mmHg or less; nine cases had one eye blind (12.5 %). Intriguingly, only eight cases (11.11 %) had been diagnosed with POAG before this screening.ConclusionsMore efforts are required for early screening and education on POAG in communities, especially in a POAG high-risk population.

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“… 1 As reported, the prevalence of glaucoma in the People’s Republic of China is approximately 1.95%–3.60%. 2 The prevalence of POAG is 0.86%–2.85% in adults aged 50 years and older living in different places in the People’s Republic of China, 3 – 7 and this is expected to rise substantially in the coming years as the population ages and the prevalence of myopia increases. There are an estimated 15 million glaucoma patients in the People’s Republic of China, including three million who are blind in one eye and 1.2 million who are blind in both eyes.…”

Section: Outline Of Chinese Glaucoma Patients and The Management Issumentioning

confidence: 99%

Fixed-combination treatments for intraocular hypertension in Chinese patients – focus on bimatoprost-timolol

Fang¹,

Ling²,

Sun³

2015

DDDT

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Glaucoma is a common eye disease that can lead to irreversible vision loss if left untreated. The early diagnosis and treatment of primary open-angle glaucoma is challenging, and visual impairment in Chinese glaucoma patients is a serious concern. Most of these patients need more than one topical antiglaucoma agent to control their intraocular pressures (IOPs). In the People’s Republic of China, the daily cost of different glaucoma medication varies greatly, and the treatment habits differ throughout the country. Prostaglandin analogs (PGAs) are recommended as first-line monotherapy, because of their efficacy and low risk of systemic side effects. Fixed-combination drops, particularly PGA-based fixed combinations, have recently been developed and used in patients with progression or who have failed to achieve their target IOPs. Here, we reviewed the current literature on the use of bimatoprost-timolol fixed combination (BTFC) in the People’s Republic of China. BTFC has achieved good efficacy and tolerability in Chinese clinical trials. In addition, BTFC is more cost effective compared with other fixed combinations available in the People’s Republic of China. Fixed-combination drops may offer benefits, such as keeping the ocular surface healthy, convenience of administration, and improvement in long-term adherence and quality of life. Therefore, BTFC has great potential for the treatment of Chinese glaucoma patients. However, the long-term efficacy of BTFC, comparisons of BTFC with other fixed-combination drugs, and treatment adherence and persistence with treatment in Chinese patients are unknown and will require further study.

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Prevalence of Glaucoma in a Rural Northern China Adult Population

Cited by 93 publications

References 25 publications

Prescribing trends of glaucoma drugs in six major cities of China from 2013 to 2017

Prescribing trends of glaucoma drugs in six major cities of China from 2013 to 2017

Prevalence and risk factors of primary open-angle glaucoma in a city of Eastern China: a population-based study in Pudong New District, Shanghai

Fixed-combination treatments for intraocular hypertension in Chinese patients – focus on bimatoprost-timolol

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Prevalence of Glaucoma in a Rural Northern China Adult Population

Cited by 93 publications

References 25 publications

Prescribing trends of glaucoma drugs in six major cities of China from 2013 to 2017

Prescribing trends of glaucoma drugs in six major cities of China from 2013 to 2017

Prevalence and risk factors of primary open-angle glaucoma in a city of Eastern China: a population-based study in Pudong New District, Shanghai

Fixed-combination treatments for intraocular hypertension in Chinese patients &ndash; focus on bimatoprost-timolol

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Fixed-combination treatments for intraocular hypertension in Chinese patients – focus on bimatoprost-timolol