Prevalence and risk factors of primary open-angle glaucoma in a city of Eastern China: a population-based study in Pudong New District, Shanghai

Abstract

BackgroundThe aim of the present study was to investigate the prevalence and characteristics of primary open-angle glaucoma among the urban population of Pudong New District, Shanghai.MethodsThree residents’ committees were randomly selected from Pudong New District, and residents aged 50 and older were screened for primary open-angle glaucoma (POAG) from March to April 2011. In remote screening, the tests on visual acuity, refraction, intraocular pressure (IOP), and the photographs of anterior segment and fundus were used to identify POAG suspect. The suspected subjects were then reexamined with the tests on IOP, gonioscopy, Humphrey visual field test, and retinal nerve fiber layer (RNFL) thickness by optical coherence tomography (OCT). POAG was diagnosed according to the criteria defined by International Society for Geographic and Epidemiological Ophthalmology (ISGEO). Finally, POAG risk factors were evaluated using logistic regression analysis.ResultsA total of 2528 citizens out of 3,146 eligible residents (80.36 %) participated in this study. Among the citizens, 72 were diagnosed to have POAG, giving the crude prevalence rate of 2.85 % (95 % CI:2.20 %–3.50 %) in general and age- and gender-adjusted prevalence rate of 2.8 % (95 % CI: 2.78 %–2.83 %). Among the 72 POAG patients, only 22 cases had IOP exceeding 21 mmHg while other 50 cases had IOP of 21 mmHg or less; nine cases had one eye blind (12.5 %). Intriguingly, only eight cases (11.11 %) had been diagnosed with POAG before this screening.ConclusionsMore efforts are required for early screening and education on POAG in communities, especially in a POAG high-risk population.

Association of serum uric acid levels with primary open‐angle glaucoma: a 5‐year case–control study

“…); 3.46% in men and 2.40% in women in the Chinese population (He et al. )]. Moreover, there was a greater number of male than female POAG participants (108 versus 55) in the present study.…”

“…In China, the prevalence of POAG is also higher in males (3.46%) than in females (2.40%), with an odds ratio of 1.47 (He et al. ). Similarly, the number of male POAG participants was greater than the number of female participants (108 versus 55).…”

Cost-effectiveness and cost-utility of population-based glaucoma screening in China: a decision-analytic Markov model

“…Compliance with community screening Rural setting 86% Liang et al, 29 Qu et al, 30 Zhong et al, 31 Song et al, 32 Sun et al 33 Urban setting 80% He et al, 14 He et al, 34 Wang et al 35 Compliance with comprehensive hospital examination Compliance with trabeculectomy among patients with PACG and moderate and severe POAG Rural setting 80% Liang et al, 29 Qu et al, 30 Song et al, 32 Pan et al 15 analysis were used to define the distribution parameters. Probabilistic uncertainty was evaluated by recalculating ICERs for 10 000 random draws from the probability distribution of each parameter.…”

To the issue of glaucoma incidence in the population of Baku city

“…According to English researchers, the proportion of people aged 40 and older with glaucoma and ocular hypertension increased from 28% in 2008 to 31% in 2012 [2]. Different age dynamics of glaucoma prevalence among men was revealed in Shanghai (2.43; 4.36; 3.91 and 1.85% aged 50 -59, 60 -69, 70 -79, 80 women (1.64; 1.96; 4.30 and 4.82%, respectively) [3]. The total incidence of glaucoma in Russia was 0.1% aged 40-49, 2.8% aged 60-69, 14.3% aged 80 years and older [4].…”