Prevalence of diseases and pathological conditions in young people under 45 years of age with abdominal obesity in Siberia

Ragino, Yu. I.; Khudyakova, A. D.; Striukova, E.V.; Денисова, Д. В.; Щербакова, Л. В.

doi:10.20538/1682-0363-2021-4-39-48

Cited by 4 publications

(1 citation statement)

References 28 publications

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“…However, there are very few such studies devoted to the peculiarities of the course of CB against the background of abdominal obesity (AO). Earlier, we reported [ 7 ] that the prevalence of CB in the young population of 25–44 years is 44.2%, and CB was 1.5 times more common in AO, which indicates the extreme urgency of this problem.…”

Section: Introductionmentioning

confidence: 84%

Blood Adipokines/Cytokines in Young People with Chronic Bronchitis and Abdominal Obesity

et al. 2022

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The pathogenesis of the development of chronic lung diseases assumes the participation of systemic inflammation factors, as well as hormone-like substances produced by adipose tissue. The aim of this study was to evaluate the associations of certain adipokines/cytokines and chronic bronchitis against the background of abdominal obesity in young people. The study included 1415 people aged 25−44. In total, 115 people were selected by the random numbers method, who were divided into two subgroups: those with chronic bronchitis and abdominal obesity and those with chronic bronchitis without abdominal obesity. A control group of patients with comparable gender and age was also selected. In the group of patients with chronic bronchitis, adiponectin, TNFa and GIP levels were 1.4 times higher. The levels of C-peptide, MCP-1 and PP in the group of chronic bronchitis were 1.3 times higher compared to the control. Adipsin, lipocalin-2, IL-6 and resistin were significantly higher in the group with chronic bronchitis. Glucagon, amylin and ghrelin were 2.2, 2.3 and 3.2 times lower, respectively, in the group of patients with chronic bronchitis. Against the background of abdominal obesity, the probability of having chronic bronchitis increased with an increase in the level of lipocalin-2 and GIP and TNFa.

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Section: Introductionmentioning

confidence: 84%

Blood Adipokines/Cytokines in Young People with Chronic Bronchitis and Abdominal Obesity

et al. 2022

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Influence of adipocytokines on the bronchopulmonary system in abdominal obesity

Khudiakova,

Ragino

2023

Pulʹmonologiâ (Mosk.)

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Pathogenesis of chronic lung diseases is assumed to involve systemic inflammation factors, as well as hormone-like substances adipokines produced by adipose tissue, which is an independent endocrine organ. Adipokines cause systemic inflammation under the influence of hypoxemia due to obesity and associated respiratory disorders such as obstructive sleep apnea syndrome, chronic obstructive pulmonary disease, hypoventilation syndrome, etc. However, the influence of specific adipocytes on the development and course of bronchopulmonary diseases remains unclear.Purpose of this review was to evaluate the contribution of some adipocytokines to the development of bronchopulmonary conditions against abdominal obesity. We collected data on adiponectin, adipsin, lipocalin-2, interleukin 6, insulin, glucagon, leptin, monocyte-chemoattractant protein type 1, tumor necrosis factor-α, amylin, glucose-dependent insulinotropic polypeptide, ghrelin, and pancreatic polypeptide in patients with abdominal obesity and bronchopulmonary disorders.Conclusion. The presented data confirm that hormone-like substances produced by adipose tissue make a significant contribution to the severity of respiratory disorders.

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Clinical variants of the metabolic syndrome in young people living in the Khanty-Mansiysk autonomous region – Yugra

Korneeva,

Voevoda

2024

Sibirskij nauchnyj medicinskij zhurnal

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Currently the “rejuvenation” and an increase in the number of components of the metabolic syndrome (MS) determine its clinical significance in the earlier development of diabetes mellitus, cardiovascular diseases and related complications. Aim of the study was to investigate the features of the MS clinic picture in a population of young men and womenliving in the Khanty-Mansiysk autonomous region – Yugra.Material and methods. The study included 863 young people between 18 and 44 years of age, including 344 men and women with MS and 519 people in the comparison group. Studied subgroups are represented by non-indigenous men and women living in urban and rural areas, and indigenous rural residents. The analysis of MS clinical and laboratory parameters was carried out and its clinical variants in ethnic groups were identified.Results and its discussion. According to the results of the survey of young people with metabolic syndrome, it was revealed that the combination of abdominal obesity and two components of MS were most common in young people with MS (in 50.0 % men and in 55.5 % women). The study defined regression models for each MS group and threshold values for waist circumference were set, which changes in lipid and carbohydrate metabolism were predicted.Conclusions. In groups with MS, hypertriglyceridemia was determined as its most common component. The study identified the most frequent association of abdominal obesity with hyper-LDL cholesterol and hypertriglyceridemia in patients with metabolic syndrome, in ethnic groups, this combination is more common in indigenous rural men (53.3 %) and in non-indigenous urban women (54.3 %).

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Prevalence of diseases and pathological conditions in young people under 45 years of age with abdominal obesity in Siberia

Cited by 4 publications

References 28 publications

Blood Adipokines/Cytokines in Young People with Chronic Bronchitis and Abdominal Obesity

Blood Adipokines/Cytokines in Young People with Chronic Bronchitis and Abdominal Obesity

Influence of adipocytokines on the bronchopulmonary system in abdominal obesity

Clinical variants of the metabolic syndrome in young people living in the Khanty-Mansiysk autonomous region – Yugra

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