Prevalence of diabetic foot disorders and related risk factors among Egyptian subjects with diabetes

Assaad-Khalil, S.; Zaki, Adel; Rehim, Abdou Abdel; Megallaa, Magdy Helmy; Gaber, Nabila; Gamal, Hesham El; Rohoma, Kamel Hemida

doi:10.1016/j.pcd.2014.10.010

Cited by 61 publications

(50 citation statements)

References 32 publications

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“…In one study, the history of DFI was found to be an independent risk factor for amputation . In another study, previous diabetic foot ulceration was associated with an active foot ulcer . In our study, the history of DFUs was found to be an independent risk factor for amputation, and there was a increase by four times in patients with a history of DFI compared with other patients.…”

Section: Discussionsupporting

confidence: 54%

Risk factors for amputation in patients with diabetic foot infection: a prospective study

Uysal

Arda

Taşbakan

et al. 2017

International Wound Journal

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There is a variety of diagnostic and therapeutic algorithms for diabetic foot infections (DFIs). Some of them are too difficult to be applied in routine clinical approach. In the routine clinical approach, it is necessary to find new risk factors and end up with a quick and easy assessment of DFIs. In this study, we aimed to evaluate the independent risk factors for osteomyelitis, amputation and major amputation in patients with DFI using standard scoring procedures. We prospectively studied 379 patients with DFI. The variables were analysed using logistic analysis. A total of 126 cases (33·2%) underwent amputation. The odds ratios in the amputation model were 3·09 for osteomyelitis (P < 0·001), 4·90 for arterial stenosis (AS) (P < 0·001), 3·67 for the history of DFI (P = 0·001), 2·47 for ulcer duration >60 days (P = 0·001), 3·10 for ulcer depth > 15 mm (P < 0·001) and 10·28 for fungal DFI (P = 0·015). In this study, the unusual result of well-known literature was fungal DFI as an independent risk factor for amputation in patients with DFI.

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Section: Discussionsupporting

confidence: 54%

Risk factors for amputation in patients with diabetic foot infection: a prospective study

Uysal

Arda

Taşbakan

et al. 2017

International Wound Journal

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“…This finding is consistent with other studies in which the prevalence ranges from 4% to 10% (Boulton et al, 2005;Assaad et al, 2015).…”

Section: Discussionsupporting

confidence: 94%

“…It has been estimated that the annual incidence of foot ulceration is approximately 1-4% (Bartus and Margolis, 2004), while the prevalence ranges from 4% to 10% (Boulton et al, 2005;Assaad et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Studying The Prevalence Of Achieving Therapeutic Goals Of Diabetes Treatment Among Diabetic Patients In Royal Medical Services

Almala

Bisharat

Ababneh

et al. 2016

ESJ

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Diabetic complications are considered a public concern on global level and have their negative impacts on patients. The main objectives of the present study were to determine the prevalence of diabetic complications among a sample of diabetics in Royal Medical Services and to conclude the appropriate recommendations to reduce the effects of diabetic complications. The method of choice involved a retrospective design and 392 files of diabetic patients were reviewed. Study findings showed that the prevalence of diabetic neuropathy was 43%, hypertension 42%, diabetic foot ulcer 9%, glaucoma 48%, and heart disease 25%. Predictors for diabetic neuropathy were the level of HbA1C (p=0.015), and gender (p=0.018), while the predictors for hypertension were duration of DM (p=0.000) and age (p=0.000). The predictors of foot ulcer included the level of HbA1C (p=0.013), and the use of metformin (p=0.026). Glaucoma was predicted by duration of DM (p=0.002), and gender (p=0.017). Heart disease was predicted by duration of DM (p=0.003), gender (p=0.041), and age (p=0.000). Taken together, diabetic complications are prevalent on global level and in our settings which implies that the therapeutic options of DM are still far from their ultimate goals. we recommend adopting of more effective monitoring systems for screening diabetics, particularly those who are expected to develop diabetes. We also recommend to activate the roles of clinical pharmacist to raise the awareness level about diabetic complications among the public.

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“…These measures have contributed significantly to the reduction of the incidence of diabetic foot. An additional layer of evidence outlining the effectiveness of these measures in reducing diabetic foot can be found in African countries such as Tanzania and Egypt [33,34]. In these countries, the introduction of the Step by Step and the Bridges Projects, involving physician and patient training on early recognition of diabetic foot, as well as multidisciplinary diabetic foot care, has resulted in a significant reduction in the incidence of diabetic foot in both countries.…”

Section: Discussionmentioning

confidence: 99%

Diabetes-related foot disorders among adult Ghanaians

Sarfo‐Kantanka

Kyei

Mbanya

et al. 2018

Diabetic Foot & Ankle

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Background: Diabetic foot remains a challenge in most low-middle-income countries (LMICs). A severe deficit in data exists on them in sub-Saharan Africa (SSA). Up-to-date data on the longitudinal trajectories and determinants can provide a benchmark for reducing diabetic foot complications in SSA. Objective: The primary objective of this study was to estimate trends in the incidence of diabetic foot and determine predictors in an adult Ghanaian diabetes cohort. Design: The study is a retrospective longitudinal study over a 12 year period. Methods: We applied Poisson regression analysis and Cox proportional hazard models to demographic and clinical information obtained from patients who enrolled in a diabetes specialist clinic in Ghana from 2005 to 2016 to identify longitudinal trends in incidence and predictors of diabetic foot. Results: The study comprised 7383 patients (63.8% female, mean follow-up duration: 8.6 years). The mean incidence of foot disorders was 8.39% (5.27% males and 3.12% females). An increase in the incidence of diabetic foot ranging from 3.25% in 2005 to 12.57% in 2016, p < 0.001, was determined. Diabetic foot, with adjusted hazard ratio (HR; 95% confidence interval (CI)), was predicted by disease duration, that is, for every 5-year increase in diabetes duration: 2.56 (1.41–3.06); male gender: 3.51 (1.41–3.06); increased body mass index (BMI), that is, for every 5 kg/m2: 3.20 (2.51–7.52); poor glycaemic control, that is, for every percentage increase in HbA1c: 1.11 (1.05–2.25), hypertension: 1.14 (1.12–3.21); nephropathy: 1.15 (1.12–3.21); and previous foot disorders: 3.24 (2.12–7.21). Conclusions: We have found a trend towards an increased incidence of diabetic foot in an outpatient tertiary diabetes setting in Ghana. Systemic and individual-level factors aimed at preventive foot screening as well as vascular risk factor control should be intensified in diabetic patients in Ghana and other LMICs. Abbreviations: BMI: Body Mass Index, BP: Blood Pressure, CI: Confidence Interval, HR: Hazard Ratio, HbA1c: Glycated Hemoglobin, PAD: Peripheral Arterial Disease, NCDs: Non Communicable Disease, SSA: Sub Saharan Africa.

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Prevalence of diabetic foot disorders and related risk factors among Egyptian subjects with diabetes

Cited by 61 publications

References 32 publications

Risk factors for amputation in patients with diabetic foot infection: a prospective study

Risk factors for amputation in patients with diabetic foot infection: a prospective study

Studying The Prevalence Of Achieving Therapeutic Goals Of Diabetes Treatment Among Diabetic Patients In Royal Medical Services

Diabetes-related foot disorders among adult Ghanaians

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