Prevalence of diabetes in the adult population of Novosibirsk

Abstract

Aims. To estimate the prevalence of type 2 diabetes mellitus (T2DM) in different age groups of the adult population of Novosibirsk, according to epidemiological studies in 20032005 and 20132016.
 Methods. We examined a representative population sample (assessed in 20032005) of men and women aged 4569 years in two administrative districts of Novosibirsk, as a part of the international HAPIEE project. According to the tables of random numbers, representative samples of men and women aged 4569 years were formed, to which letters were sent, inviting them to pass for examination. During 20132016, a second population survey was conducted on a random representative sample of a population of 2544-year-olds of both sexes. Participants were residents of one of the districts of Novosibirsk. T2DM and impaired fasting glucose (IFG) were diagnosed using fasting plasma glucose (FPG) levels (diabetes: FPG 7.0 mmol/l; IFG: FPG 6.16.9 mmol/l).
 Results. The prevalence of T2DM among residents aged 4569 years was 11.3%, and overall, no significant difference in prevalence was found between females and males (11.3% vs. 11.0%).
 However, the overall prevalence of T2DM among residents aged 2544 years was 2.2%, and prevalence was higher in men (3.5%) than in women (1.1%), p 0.05.
 High prevalence of IFG was found in the 4569 age group (18.2%, in 20032005), and in the younger age group of 2544 years (21.6%, in 20132016). The high rate among young individuals is particularly alarming.
 Less than one half (4.8 out of 11.3%) of participants aged 4569 tested positive for T2DM, and only one in the age group 2544 years knew he/she had diabetes. This indicates a lack of knowledge among Siberians about their problem with diabetes.
 Conclusion. Approximately one in five adults had IFG. Among the adult population aged 4569 (in 20032005), 18.2% had IFG and 11.3% had T2DM. In individuals aged 2544 years in 20132016, IFG was observed in 21.6%, and 2.2% had T2DM (p0.05).

What factors explain the much higher diabetes prevalence in Russia compared with Norway? Major sex differences in the contribution of adiposity

“…8 The ESSE-RF study (10 regions of the Russian Federation, 2012-2014) estimated the prevalence of diabetes mellitus based on self-report and fasting glucose: 9.4% of men and 7.4% of women aged 45-54 years old and 13.6% of men and 16.5% of women aged 55-64 years old had diabetes mellitus. 9 Similarly to our study, other studies conducted in Russia report that a high proportion of diabetes is undiagnosed: 54% in NATION study, 8 43% in HAPIEE, 10 and 27% in UEMS. 11 Differences between these estimates and estimates from our study can be explained by the different age structures of the studied populations, different access to healthcare services in Russian regions, and different methods for diabetes prevalence estimates.…”

“…5 Data on type 2 diabetes prevalence in Russia have been reported in a few population-based studies based either on glycated hemoglobin [6][7][8] or fasting glucose. [9][10][11] These studies report relatively high prevalence of type 2 diabetes in Russia ranging from 7% to 16%, with the highest burden being in women compared with men at older ages.…”

Triglycerides, Obesity and Education Status Are Associated with the Risk of Developing Type 2 Diabetes in Young Adults, Cohort Study

“…In general, our data are consistent with previous studies. The prevalence of T2DM in young adults in Novosibirsk was studied earlier and amounted to 2.2% [11], which is consistent with the all-Russian data of the NATION study. According to the results of this study, 0.82% of people in the study developed T2DM (taking into account the fact that patients with a history of T2DM were excluded from the analysis).…”

The Profile of Glucose Lowering Therapy in Persons with Type 2 Diabetes Mellitus in an Aging Russian Population

“…In the Russian Federation (RF), a similar situation has been observed, and, according to the Russian Diabetes Register, this figure had reached 4.58 million people (3.1% of the population) by 1 January 2019 [ 2 ]. According to our early data, DM2 was found in 11.4% of subjects in a population sample aged 45–69 years in Novosibirsk [ 3 , 4 ].…”