Prevalence of COPD in Five Colombian Cities Situated at Low, Medium, and High Altitude (PREPOCOL Study)

Caballero, Andrés; Torres-Duque, Carlos A.; Jaramillo, Claudia; Bolívar, Fabio; Sanabria, Fernando; Osorio, Patricia; Orduz, Carlos; Guevara, Diana P.; Maldonado, Darío

doi:10.1378/chest.07-1361

Cited by 258 publications

(242 citation statements)

References 39 publications

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“…Approximately half of those prevalences remained unexplained after adjustment for covariates. CABALLERO et al [21] found prevalences of GOLD stage I COPD (FEV1/FVC ,0.7) ranging 6-13% in Colombia and the international Burden of Obstructive Lung Disease (BOLD) study identified prevalences in males ranging from 11% in China to 24% in South Africa [22]. Overall, the evidence suggests substantial geographical variation in COPD prevalence that remains largely unexplained.…”

Section: Discussionmentioning

confidence: 98%

COPD prevalence and its association with occupational exposures in a general population

Melville¹,

Pless‐Mulloli²,

Afolabi³

et al. 2010

European Respiratory Journal

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The aim of this study was to ascertain the population prevalence of chronic obstructive pulmonary disease (COPD) in an area with past heavy industry and to establish the relative contributions of occupational and other risk factors.We investigated respiratory symptoms and the prevalence of spirometrically-defined COPD in a population-based study in North-East England (UK) between 2002 and 2004. Questionnaires were posted to 6,000 males and 6,000 females, 45-69 yrs of age, who were randomly selected from a primary care database (response rate 64%, n57,566). Spirometric measurements were performed on 845 randomly selected responders. We defined COPD by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) II criteria.The prevalence of respiratory symptoms was 55%. Symptoms were strongly associated with smoking, occupational exposures and hay fever. COPD was present in 10% of subjects. Its presence was significantly associated with occupational exposures, smoking and hay fever.COPD is common in North-East England. Respiratory effects of occupational exposures can be detected within the general population: there were clear associations between occupational exposures and respiratory symptoms. The association with COPD was more marked in females.

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Section: Discussionmentioning

confidence: 98%

COPD prevalence and its association with occupational exposures in a general population

Melville¹,

Pless‐Mulloli²,

Afolabi³

et al. 2010

European Respiratory Journal

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“…[2] In a number of large population-based cross-sectional studies, PTB has also been shown to be strongly associated with the presence of chronic airflow limitation (CAL). [3][4][5][6] In some studies, this association is almost as strong as that for cigarette smoking. [5][6][7] In a community-based study performed in South Africa (SA), 49.2% of adults aged ≥40 years who reported a history of PTB had evidence of CAL (Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage 1 or higher).…”

Section: Researchmentioning

confidence: 95%

Obstructive pulmonary disease in patients with previous tuberculosis: Pathophysiology of a community-based cohort

et al. 2017

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Background. An association between chronic airflow limitation (CAL) and a history of pulmonary tuberculosis (PTB) has been confirmed in epidemiological studies, but the mechanisms responsible for this association are unclear. It is debated whether CAL in this context should be viewed as chronic obstructive pulmonary disease (COPD) or a separate phenotype. Objective. To compare lung physiology and high-resolution computed tomography (HRCT) findings in subjects with CAL and evidence of previous (healed) PTB with those in subjects with smoking-related COPD without evidence of previous PTB. Methods. Subjects with CAL identified during a Burden of Obstructive Lung Disease (BOLD) study performed in South Africa were studied. Investigations included questionnaires, lung physiology (spirometry, body plethysmography and diffusing capacity) and quantitative HRCT scans to assess bronchial anatomy and the presence of emphysema (<-950 HU), gas trapping (<-860 HU) and fibrosis (>-200 HU). Findings in subjects with a past history and/or HRCT evidence of PTB were compared with those in subjects without these features. Results. One hundred and seven of 196 eligible subjects (54.6%) were enrolled, 104 performed physiology tests and 94 had an HRCT scan. Based on history and HRCT findings, subjects were categorised as no previous PTB (NPTB, n=31), probable previous PTB (n=33) or definite previous PTB (DPTB, n=39). Subjects with DPTB had a lower diffusing capacity (Δ=-17.7%; p=0.001) and inspiratory capacity (Δ=-21.5%; p=0.001) than NPTB subjects, and higher gas-trapping and fibrosis but not emphysema scores (Δ=+6.2% (p=0.021), +0.36% (p=0.017) and +3.5% (p=0.098), respectively). Conclusions. The mechanisms of CAL associated with previous PTB appear to differ from those in the more common smoking-related COPD and warrant further study.

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“…COPD is a frequent cause of mortality, increased morbidity and decreased quality of life 20,21 . Due to the aging of the population and deteriorating air pollution, the global incidence and prevalence of the disease is increasing.…”

Section: Epidemiologymentioning

confidence: 99%

Chronic Obstructive Pulmonary Disease: Official diagnosis and treatment guidelines of the Czech Pneumological and Phthisiological Society; a novel phenotypic approach to COPD with patient-oriented care

Koblížek

Chlumský²,

Zindr³

et al. 2013

BIOMED PAP

125

116

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Prevalence of COPD in Five Colombian Cities Situated at Low, Medium, and High Altitude (PREPOCOL Study)

Cited by 258 publications

References 39 publications

COPD prevalence and its association with occupational exposures in a general population

COPD prevalence and its association with occupational exposures in a general population

Obstructive pulmonary disease in patients with previous tuberculosis: Pathophysiology of a community-based cohort

Chronic Obstructive Pulmonary Disease: Official diagnosis and treatment guidelines of the Czech Pneumological and Phthisiological Society; a novel phenotypic approach to COPD with patient-oriented care

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