Prevalence of clinically validated primary causes of end-stage renal disease (ESRD) in a State Capital in Northeastern Brazil

Sarmento, Luana; Fernandes, Paula Frassinetti Castelo Branco Camurça; Pontes, Marcelo Ximenes; Correia, Daniel Barros Santos; Chaves, Victhor Castelo Branco; Carvalho, Cecília Ferreira de Araújo; Arnaud, T.; Santos, Matheus Henrique Seixas dos; Barreto, Lívia; Moliterno, Larissa Alves Alexandre

doi:10.1590/2175-8239-jbn-3781

Cited by 23 publications

(31 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In this perspective, our results have demonstrated that serum and salivary levels of calcium, urea, and creatinine exhibit significant statistical differences (p<0.001). Our findings are consistent with previous studies [2,[29][30][31][32], adding to the existing data to support the possibility of employing analysis of salivary creatinine and urea for the diagnosis and assessment of CRF [33].…”

Section: Discussionsupporting

confidence: 92%

“…Concerning age, our findings demonstrated that most patients had an age greater than or equal to 40 years old, which corroborates the results of some studies [5,12,24,25]. In Brazil, the prevalence of CRF is high; approximately 11 to 22 million adults are estimated to have some degree of renal dysfunction in a population of about 200 million and 70% of the adult population [2]. In the Brazilian Northeast exist 134 dialysis units, and our study corresponded to approximately 3% of this totality.…”

Section: Discussionsupporting

confidence: 90%

“…According to The Global Burden of Disease study is estimated that 1.2 million people have died of kidney failure, with an increase of 32.0% since 2005. It has been observed that 5 to 10 million people die each year from kidney disease [1][2][3][4]. Chronic renal failure (CRF) is a progressive disease characterized by the gradual destruction of nephrons and a consequent reduction of kidney function occurring over a few months or years [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Salivary and Serum Biochemical Analysis from Patients with Chronic Renal Failure in Hemodialysis: A Cross-Sectional Study

Gonçalves

Pessoa

Leitão

et al. 2021

Pesqui. Bras. Odontopediatria Clín. Integr.

View full text Add to dashboard Cite

Objective: To compare salivary and serum biochemical levels in patients with chronic renal failure undergoing hemodialysis. Material and Methods: The sample was composed of 57 patients treated in Hemodialysis Reference Centers, from a state of Northeastern Brazilian, with age ≥21 years old with at least 3 months of hemodialysis treatment time. Serum data were obtained from records. Unstimulated and stimulated saliva were collected. Flow rate (mL/min) was measured. Spectrophotometry was performed for the measurement of salivary levels of calcium (570 nm), urea (340 nm), and creatinine (510 nm). Statistical analysis used Mann Whitney and Kruskal-Wallis tests (p<0.05). Results: Unstimulated and stimulated salivary flow rates were 0.43 mL/min and 1.69 mL/min, respectively. There was significant difference (p<0.001) of levels of calcium (5.41 mg/dL and 9.70 mg/dL), urea (118.03 mg/dL and 183.22 mg/dL) and creatinine (0.59 mg/dL and 9.20 mg/dL) between saliva and serum, respectively. Concerning the time of hemodialysis, salivary and serum calcium not exhibited significant association; however, serum urea (p=0.012) and serum creatinine (p=0.025) showed significant association to the time of hemodialysis. Conclusion: Salivary biochemical levels of urea, creatinine and calcium can indicate the presence of a possible chronic renal failure and the saliva demonstrated to be a potential auxiliary biofluid for clinical monitoring renal alterations.

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Salivary and Serum Biochemical Analysis from Patients with Chronic Renal Failure in Hemodialysis: A Cross-Sectional Study

Gonçalves

Pessoa

Leitão

et al. 2021

Pesqui. Bras. Odontopediatria Clín. Integr.

View full text Add to dashboard Cite

show abstract

“…In these cases, renal biopsy is an important method to confirm the etiology of this glomerular disease 2 . In Brazil, data regarding trends in glomerular and nonglomerular nephropathies confirmed by means of a renal biopsy are still limited to certain regions of the country [3][4][5][6] or based on sampling from hospitals/ nephrology centers 3,5,[7][8][9][10][11][12][13] . In Santa Catarina, there are no population data that can contribute to a better epidemiological understanding of the prevalence of nephropathies diagnosed through renal biopsy.…”

Section: Abstract Introductionmentioning

confidence: 99%

“…In the multivariate analysis, among the primary glomerulopathies, males had a higher risk for the occurrence of IgAN [OR=2.02; 95% CI 1. 13…”

mentioning

confidence: 99%

Distribution of kidney diseases in Joinville, Santa Catarina: analysis of a kidney biopsy data bank between 2008 and 2019

et al. 2022

View full text Add to dashboard Cite

Introduction: Studies based on kidney biopsies are important for the epidemiological understanding of nephropathies. Objective: To describe the main nephropathies diagnosed through renal biopsies, and compare them with regards to gender, time, healthcare insurance and age. Methods: A population-based retrospective study that reviewed all kidney disease diagnoses obtained by biopsy of a native kidney from pathology services between 2008 and 2019 in Joinville, Brazil. Results: Of 778 biopsies performed, 44.5% were primary nephropathies and 28.5% were secondary. The highest prevalence was focal segmental glomerulosclerosis (FSGS) [18.1%], followed by tubulointerstitial nephropathy (TIN) [15.9%] and IgA nephropathy (IgAN) [9.1%]. There was a growing increase in the prevalence of TIN among elderly and uninsured patients over the period. In the multivariate analysis, among the primary glomerulopathies, males had a higher risk for the occurrence of IgAN [OR=2.02; 95% CI 1.13-3.61; p=0.018], as well as being a protective factor for the occurrence of lupus glomerulonephritis (LGN) [OR=0.20, 95% CI 0.08-0.49; p<0.001]. Advancing age and dependence on a public healthcare decreased the likelihood of having a diagnosis of LGN [OR=0.91, 95% CI 0.88-0.94, p < 0.001 and OR=0.45, CI 95 % 0.21-0.96; p = 0.036, respectively]. Patients without private healthcare insurance were more likely to have TIN [OR=1.77, 95%CI 1.16-2.70; p = 0.008]. Conclusion: Sex, age and type of medical healthcare insurance may be related to the occurrence of some nephropathies. The increased risk of TIN in individuals without a private healthcare plan may be an indication of inequalities in health care.

show abstract

Development and Validation of an Application for Follow-up of Patients Undergoing Dialysis: NefroPortátil

Pinto

Andrade

Chaves

et al. 2020

Journal of Renal Nutrition

View full text Add to dashboard Cite

Prevalence of clinically validated primary causes of end-stage renal disease (ESRD) in a State Capital in Northeastern Brazil

Cited by 23 publications

References 7 publications

Salivary and Serum Biochemical Analysis from Patients with Chronic Renal Failure in Hemodialysis: A Cross-Sectional Study

Salivary and Serum Biochemical Analysis from Patients with Chronic Renal Failure in Hemodialysis: A Cross-Sectional Study

Distribution of kidney diseases in Joinville, Santa Catarina: analysis of a kidney biopsy data bank between 2008 and 2019

Development and Validation of an Application for Follow-up of Patients Undergoing Dialysis: NefroPortátil

Contact Info

Product

Resources

About