Prevalence of chronic kidney disease and its association with cardio-metabolic risk factors in the adult Romanian population: the PREDATORR study

Abstract

The PREDATORR study showed a high prevalence of chronic kidney disease in the adult Romanian population providing data on its prognosis and association with several cardio-metabolic risk factors.

Metabolic syndrome and its components are associated with increased chronic kidney disease risk: Evidence from a meta-analysis on 11 109 003 participants from 66 studies

“…Of this, 12 studies assessed obesity based on body mass index (BMI), 9,28,36,43,45,56,65,71,72,76,79 ,83 and 35 studies used waist circumference for the assessment of obesity. 12,21,23,24,26,27,[33][34][35][38][39][40]42,44,47,48,[51][52][53][54][55][57][58][59][60][61][62][63][64]67,69,[73][74][75]82 The overall CKD risk related to higher BMI/waist circumference, as compared with lower BMI/waist circumference, was 1.22 (95% CI = 1.12-1.31), and was greater for higher values of waist circumference than BMI (Figure 3). In the stratified analysis by ethnicity, sex, and study type, the increased risk associated with higher values of BMI/waist circumference was significant in different subgroups.…”

“…The relationship between HDL-cholesterol level and CKD risk was examined in 45 studies, 9,12,21,23,24,[26][27][28][33][34][35][36][38][39][40]42,44,48,[51][52][53][54][55][56][57][58][59][60][61][62][63][64][65][67][68][69][71][72][73][74][75][76]79,82,83 including 692 780 patients and 11 039 480 participants. In the overall analysis, the risk estimate for lower values of HDL-cholesterol, as compared with higher values, was 1.20 (95% CI = 1.11-1.30).…”

A Cross-Sectional Survey on Lipid Abnormalities Associated With Nondiabetic Subjects With Chronic Ki

“…In other studies, Ashar Alam et al, which looked at the prevalence and risk factors of kidney disease in urban Karachi, 350 patients were studied, of which, 91.4% were nondiabetic showed that 54.3% patients had dyslipidaemia. 3 M. Mota et al in their study 4 looked at cardiometabolic parameters in nondiabetic patients with chronic kidney disease in Romania, and in this study, dyslipidaemia was present in 90%. Hence, the findings in our study were somewhere in between the results obtained by the other authors.…”

The Inflammatory Marker HSCRP as a Predictor of Increased Insulin Resistance in Type 2 Diabetics without Atherosclerotic Manifestations

“…The only metabolic profile parameters which correlated significantly with insulin resistance were HDL-cholesterol with HOMA-IR (r = -0.24, p = 0.007), triglycerides with HOMA C-peptide (r = 0.19, p = 0.03) and uric acid with HOMA C-peptide (r = 0.28, p = 0.001). These results bear clinical relevance in themselves but also in light of diabetics' known predisposition to developing long term complications such as chronic kidney disease (CKD), in which case levels of HOMA-IR, uric acid and triglycerides tend to be higher or even predict CKD [11].…”