Prevalence of Chronic Kidney Disease and Associated factors among Patients with Kidney Problems Public Hospitals in Addis Ababa, Ethiopia

Kore, Cheru; Hm, Yohannes

doi:10.4172/2472-1220.1000162

Cited by 6 publications

(2 citation statements)

References 32 publications

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“…4 Institution-based studies in Ethiopia show that the prevalence of CKD ranges from 22.1% to 38.6%. [5][6][7] Chronic kidney disease leads to hypertension, anemia, vascular dysfunction, uremia, proteinuria, systemic inflammation, and oxidative stress that are associated with cognitive impairment. 8,9 Cognitive impairment is when a person has trouble remembering, learning new things, concentrating, or making decisions which is a common problem affecting CKD patients.…”

Section: Introductionmentioning

confidence: 99%

Cognitive Impairment and Associated Factors Among Chronic Kidney Disease Patients: A Comparative Cross-Sectional Study

Gela¹,

Getu²,

Adane³

et al. 2021

NDT

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Background: Cognitive impairment is one of the public health problems affecting 50 million people in the world. Chronic kidney disease (CKD) patients are at high risk to develop cognitive impairment which leads to poor quality of life, difficulty in adhering to medications, increased risk of mortality, and health resource utilization. However, there is no study done on the prevalence of cognitive impairment and associated factors among chronic kidney disease patients in Ethiopia. Objective: This study aimed to assess the prevalence of cognitive impairment and associated factors among chronic kidney disease patients at the University of Gondar Comprehensive Specialized and Felege Hiwot Referral Hospitals in 2020, Northwest Ethiopia, 2020. Methods: An institution-based comparative cross-sectional study was conducted at the University of Gondar Comprehensive Specialized and Felege Hiwot Referral Hospitals in 2020. A systematic random sampling technique was used to select the study participants. Data were collected using standard tools. Data were checked for its completeness and entered into Epi data version 3.0 then exported into STATA 14. Multi-variable logistic regression analysis was employed to identify associated factors of cognitive impairment among CKD patients, and variables having a p-value of ≤0.05 were declared as significant. Results: In this study, 116 CKD patients and 116 age, sex, and educational level matched controls were included with a response rate of 100%. The prevalence of cognitive impairment was 49.1% [95% CI (40%, 58.3%)] among CKD patients and 28.4% [95% CI (20.9%, 37.5%)] among controls. Independent predictors of cognitive impairment among CKD patients were estimated glomerular filtration (eGFR) <60mL/min/m 2 [AOR=3.9, 95% CI (1.1-14.74)], proteinuria [AOR=6.0, 95% 3)], age greater than 65 years [AOR=4.0, 95% CI (1.12-14.64)], and educational level of grade 8 and less [AOR= 4.7,]. Conclusion:The prevalence of cognitive impairment among CKD patients was higher than healthy controls. Cognitive impairment was higher among CKD patients with eGFR <60mL/ min/m 2 , proteinuria, educational level of grade 8 and less, and age greater than 65 years. Therefore, there is a need to have a regular evaluation and follow-up of CKD patients for cognitive impairment.

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Section: Introductionmentioning

confidence: 99%

Cognitive Impairment and Associated Factors Among Chronic Kidney Disease Patients: A Comparative Cross-Sectional Study

Gela¹,

Getu²,

Adane³

et al. 2021

NDT

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show abstract

“…Sample size was calculated using single population proportion formula by considering the following parameters: 10.4% proportion of chronic Kidney Diseases from previous study (10), 95% confidence interval and 5% margin of error. Since the total number of patients on follow up care was less than 10,000, sample size was adjusted by using finite population correction formula.…”

Section: Methodsmentioning

confidence: 99%

Epidemiology of Chronic Kidney Diseases in Ethiopian Police Hospital: Institutional based cross sectional study

Abdulkadr¹,

Merga²,

Abdissa³

et al. 2019

Preprint

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Background Diabetes mellitus remains the leading cause of end stage renal disease in most countries in the world. In Ethiopia, renal complications of diabetes may remain unrecognized due to limited diagnostic resources. As a result, the studies that shows the prevalence of chronic kidney disease (CKD) and its risk factors among adult diabetics in Ethiopia are flimsy. Hence, this study was aimed at assessing the prevalence of chronic kidney disease and associated factors among diabetic patients who attended federal police hospital diabetic clinic in Addis Ababa. Methods Hospital based cross sectional study was conducted among 362 Diabetes Mellitus patients using systematic sampling method. Chronic kidney disease stage was categorized according to the classification system established by the National Kidney Foundation Kidney Disease out comes Quality Initiative and defined by Estimated Glomerular Filtration Rate (eGFR) <60ml/min/1.73m2. Analysis was performed using SPSS. The prevalence estimates for the reduced GFR and overall chronic kidney disease were obtained. Binary logistic regression was used to see associated factors with chronic kidney disease. Results The prevalence of chronic kidney disease diagnosed by Cockroft-Gault equation and Modification of Diet in Renal Disease equation was 14.6% and 7.7% respectively. Age 50-59 years (AOR= 4.0; 95% CI:1.2, 13) by Cockroft-Gault equation (CG), age 60-69 years (AOR=5.8 95%CI:1.5,21.0) by Modification of Diet in Renal Disease (MDRD) and (AOR;22.9 95%CI:7.1,74.2) by CG, age 70 years and above (AOR=4.7; 95 CI: 1.1, 19.7) by MDRD and (AOR= 22.9; 95%CI:7.1,74.2) by CG, BMI (AOR=2.2; 95% CI:1.6, 4.2) by CG, and previous kidney disease (AOR=6.2 95%CI:2.0,8.4) by MDRD and (AOR;4.6 95%CI:1.9,10.8) C-G equation were found to have a significant association with chronic kidney disease after an adjustment done using multivariate analysis. Conclusion The prevalence of chronic kidney disease among Diabetic patients in this study was high. Age, BMI and previous recurrent kidney disease were associated with Chronic Kidney Disease. Preventive measures like giving health education and screening of patients with risk factors should get more attention.

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Development of Chronic Kidney Disease Risk Prediction and Management System- Research study

Asmare

Thamineni

Dasari

et al. 2023

Preprint

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Background: Chronic kidney disease is one of a major global public health issue, affecting over 10% of the population worldwide. It is the leading cause of death in 2016 ranking 16th and is expected to rise to 5th rank by 2040.Consequently, tools to identify patients at high risk of having CKD and management of risk factors are needed, particularly in limited-resources settings where laboratory facilities are scarce. This study aimed to develop a risk prediction and management system using data from JUMC, SPHMMC and MTUTH. Objective: To develop chronic kidney disease risk prediction and management system is using expert system. Method :General chronic kidney disease risk factor were collected from expert knowledge .The identified general risk factors were applied on 384 patients data collected from three hospitals to identify risk factors in Ethiopia .The risk factors were identified using statistical analysis .After identifying the risk factors from the statistical analysis ,risk factor managements techniques were identified from expert knowledge. Knowledge gained from the expert knowledge and statistical analyses were combined and developed using rule based expert system. Main outcome measure: Accuracy, Precision and recall are the parameters which have been evaluated from the developed system using confusion matrix. Result: The system has showed 63.3 %, 65.3 %and 77.5%accuracy at 14%, 24% and 34% cut off percent respectively in estimating probability. Conclusion: This study will have significance in preventing chronic kidney disease at early stage and creating awareness. Funding Statement: The authors received no specific funding for this study.

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Prevalence of Chronic Kidney Disease and Associated factors among Patients with Kidney Problems Public Hospitals in Addis Ababa, Ethiopia

Cited by 6 publications

References 32 publications

Cognitive Impairment and Associated Factors Among Chronic Kidney Disease Patients: A Comparative Cross-Sectional Study

Cognitive Impairment and Associated Factors Among Chronic Kidney Disease Patients: A Comparative Cross-Sectional Study

Epidemiology of Chronic Kidney Diseases in Ethiopian Police Hospital: Institutional based cross sectional study

Development of Chronic Kidney Disease Risk Prediction and Management System- Research study

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