Epidemiology of Chronic Kidney Diseases in Ethiopian Police Hospital: Institutional based cross sectional study

Abstract

Background Diabetes mellitus remains the leading cause of end stage renal disease in most countries in the world. In Ethiopia, renal complications of diabetes may remain unrecognized due to limited diagnostic resources. As a result, the studies that shows the prevalence of chronic kidney disease (CKD) and its risk factors among adult diabetics in Ethiopia are flimsy. Hence, this study was aimed at assessing the prevalence of chronic kidney disease and associated factors among diabetic patients who attended federal police hospital diabetic clinic in Addis Ababa. Methods Hospital based cross sectional study was conducted among 362 Diabetes Mellitus patients using systematic sampling method. Chronic kidney disease stage was categorized according to the classification system established by the National Kidney Foundation Kidney Disease out comes Quality Initiative and defined by Estimated Glomerular Filtration Rate (eGFR) <60ml/min/1.73m2. Analysis was performed using SPSS. The prevalence estimates for the reduced GFR and overall chronic kidney disease were obtained. Binary logistic regression was used to see associated factors with chronic kidney disease. Results The prevalence of chronic kidney disease diagnosed by Cockroft-Gault equation and Modification of Diet in Renal Disease equation was 14.6% and 7.7% respectively. Age 50-59 years (AOR= 4.0; 95% CI:1.2, 13) by Cockroft-Gault equation (CG), age 60-69 years (AOR=5.8 95%CI:1.5,21.0) by Modification of Diet in Renal Disease (MDRD) and (AOR;22.9 95%CI:7.1,74.2) by CG, age 70 years and above (AOR=4.7; 95 CI: 1.1, 19.7) by MDRD and (AOR= 22.9; 95%CI:7.1,74.2) by CG, BMI (AOR=2.2; 95% CI:1.6, 4.2) by CG, and previous kidney disease (AOR=6.2 95%CI:2.0,8.4) by MDRD and (AOR;4.6 95%CI:1.9,10.8) C-G equation were found to have a significant association with chronic kidney disease after an adjustment done using multivariate analysis. Conclusion The prevalence of chronic kidney disease among Diabetic patients in this study was high. Age, BMI and previous recurrent kidney disease were associated with Chronic Kidney Disease. Preventive measures like giving health education and screening of patients with risk factors should get more attention.

Prevalence of chronic kidney disease and associated factors among patients with chronic illness in Ethiopia: A systematic review and meta-analysis

“…The highest magnitude of CKD is reported from Jimma University medical center (38.9%) 29 while the least is from Zewditu memorial hospital (12.2%). 30 The studies were conducted in five different regions of the country; 4 from Addis Ababa, 19 , 26 , 30 , 31 4 from Amhara, 20 , 21 , 27 , 28 2 from Oromia, 22 , 29 and 1 from SNNPR. 32 …”