Prevalence of Bacterial Urinary Tract Infections and Associated Factors among Patients Attending Hospitals in Bushenyi District, Uganda

Abstract

Urinary tract infections (UTIs) are one of the major causes of morbidity and comorbidities in patients with underlying conditions, and it accounts for the majority of the reasons for hospital visit globally. Sound knowledge of factors associated with UTI may allow timely intervention that can easily bring the disease under control. This study was designed to determine the prevalence of UTI by isolating and characterizing the different bacterial etiological agents and to evaluate the factors associated with UTI. In this cross-sectional study, a total of 267, clean catch midstream urine (MSU) samples were collected aseptically and analyzed using standard microbiology methods. Data for the factors associated with UTI were obtained by use of questionnaires and standard laboratory tests for selected underlying conditions. The study revealed 86/267 (32.2%) UTI prevalence among patients attending hospitals in Bushenyi District, Uganda. Escherichia coli was the most prevalent bacterial uropathogen with 36/86 (41.9%) followed by Staphylococcus aureus 27/86 (31.4%), Klebsiella pneumoniae 10/86 (11.6%), Klebsiella oxytoca 6/86 (7.0%), Proteus mirabilis 3/86 (3.5%), Enterococcus faecalis 3/86 (3.5%), and Proteus vulgaris 1/86 (1.2%). This study has demonstrated that age ≤19 years, female gender, married individuals, genitourinary tract abnormalities, diabetes, hospitalization, indwelling catheter <6 days, and indwelling catheter >6 days had statistically significant relationships (p<0.05) with UTI. Screening for UTI in hospitalized patients, female gender, married individuals, genitourinary tract abnormalities, indwelling catheter, and diabetics should be adopted.

Antibiotic sensitivity pattern in urinary tract infection among adults in central part of Nepal

“…Overall prevalence of UTI in this study was found to be 13.5% with higher prevalence among females (23.1%) than in the males (6.2%). The prevalence of UTIs in the current study is similar to the finding by Pradhan et al 13 but is lower than the studies by Mwaka et al (10%), 14 Tibyangye et al (22%) 15 and Odoki et al (32%) 16 from Uganda; and Khatiwada et al from Nepal. 17 The possible explanation for the variation in the prevalence in these studies could be the differences in the types of the populations studied.…”

Prevalence and Antibiogram Characteristics of Bacteriuria and Cadidiuria among Indigenes of Selected Parts of Akure North, Ondo State

“…This present study also implicated Ipogun-Ayo to have the highest prevalence of (28.72%). The presence of these organisms in urine samples was however, substantial to the findings of [21,22]. Staphylococcus aureus to be the most frequently occurred uropathogen with 27.2%.…”

“…is common to cause urinary tract infections in younger persons. Odoki et al, [21] also recorded S. aureus to be more prominent to cause UTIs among pregnant women in Uganda.…”

Prevalence and antibiotic susceptibility of urinary tract infections in febrile children below ten years attending mulago hospital, Uganda

“…These findings concur with those in similar studies carried out in Europe and Asia. The predominance of Enterobacteriaceae could be due to their omnipresence in the environment (18,19). Furthermore, Escherichia coli is the most predominant normal aerobic intestinal flora with various strains of specific virulence factors that interact with the host to overcome host defenses in the urinary tract and to stimulate an infection.…”