Prevalence of Apical Periodontitis and Conventional Nonsurgical Root Canal Treatment in General Adult Population: An Updated Systematic Review and Meta-analysis of Cross-sectional Studies Published between 2012 and 2020

Abstract

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Prevalence and risk factors of Apical periodontitis in endodontically treated teeth: cross-sectional study in an Adult Moroccan subpopulation

“…As well as many studies, the present study revealed that both of the root canal filling and coronal restoration quality are equally important for the periapical health in endodontically treated teeth [9,33]. According to the present study, when the root canal filling was inadequate, the good coronal seal did not prevent AP in endodontically treated teeth (Fig.…”

“…5% of endodontically treated teeth with inadequate root canal treatment, and AP in their study was significantly associated with insufficient root canal fillings (P < 0.05) [5]. Moreover, in a Meta-analysis of previous crosssectional studies published between 2012 and 2020, Jakovljevich et al, had shown a significant higher prevalence of AP in treated teeth with inadequate root canal treatment (OR = 4.65; 95% CI 2.75-7.84; p < 0.00001), and a significant higher prevalence of AP in ETT with poor coronal restoration (OR = 1.54; 95% CI 1.16-2.05, p = 0.003) [9], these findings are all in accordance with the results of the present study. The interpretation of radiographs is the most common method used to evaluate AP in epidemiological studies [11,34], clinical symptoms such as pain, swelling, sinus tract formation and tenderness are moderately specific.…”

“…A Meta-analysis of previous cross-sectional studies, has shown a significant higher prevalence of AP in treated teeth with inadequate root canal treatment (OR = 4.65; 95% CI 2.75-7.84; p < 0.00001), and a significant higher prevalence of AP in ETT with poor coronal restoration (OR = 1.54; 95% CI 1.16-2.05, p = 0.003) [3,[9][10][11][12][13][14].…”

“…An updated systematic review of cross-sectional studies published between 2012 and 2020 [9], revealed a worrying increase in the worldwide prevalence of AP among endodontically treated teeth (from 35.9% to 41.3%). These results enhance the need for further investigations of risk factors of AP in ETT, especially because of the growing evidence of AP impact on impaired systemic health (eg, diabetes mellitus, cardiovascular diseases) [15,16].…”

Ultrasound imaging for the differential diagnosis of periapical lesions of endodontic origin in comparison with histopathology – a systematic review and meta‐analysis

“…Occasionally, lesions in the periapical region can also develop due to nonodontogenic causes (Rodrigues & Estrela 2008, Moraes Ramos-Perez et al 2010. Jakovljevic et al (2020) in their systematic review reported that 6.3% of teeth in the general adult population had apical periodontitis.…”