Prevalence of antibodies against feline panleukopenia virus in client-owned cats in Southern Germany

Mende, Katherina; Stuetzer, Bianca; Sauter‐Louis, Carola; Homeier, Timo; Truyen, Uwe; Hartmann, Katrin

doi:10.1016/j.tvjl.2013.12.023

Cited by 26 publications

(44 citation statements)

References 23 publications

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“…In this study, 44% of the diseased animals were aged under 6 months and 72% were unvaccinated, suggested that those would not be protected against infection by FPV at the time of contact with the virus in the environment, supporting previous observations [e.g. Mende et al (2014)]. However, in a recent study, Truyen and Parrish (2013) showed that 37% of the cats that were infected had been vaccinated at least once.…”

Section: Discussionsupporting

confidence: 82%

See 1 more Smart Citation

Genetic Analysis of Feline Panleukopenia Virus Full-length VP2 Gene in Domestic Cats Between 2006-2008 and 2012-2014, Portugal

Miranda

Vieira

Silva

et al. 2016

Transbound Emerg Dis

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Feline panleukopenia virus (FPV) and canine parvovirus (CPV) are two closely related viruses, which cause acute gastroenteritis in carnivores, and cats may be infected by strains of both viruses. The viruses are found worldwide and may have changing host ranges and genetic variation that can be found around the world in some cases. Here, we screened a Portuguese population of cats by a conventional PCR assay for the presence of FPV/CPV viruses in faecal samples and tissues between 2006-2008 and 2012-2014. The sequence analysis of the complete VP2 gene showed that 18 of 31 animals tested were positive for FPV DNA, and no case of CPV infection was detected. The analysis of specific DNA detected three new non-synonymous substitutions in the VP2 gene that were found in single groups and were related to viruses reported elsewhere by phylogenetic analysis - some were related to Italian isolates, one was closely related to isolates from Vietnam and China, and two were related with older strains from the USA. The results of our study show that FPV circulated in the Portuguese cat population and as expected the found strains are slightly divergent from those reported previously.

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Section: Discussionsupporting

confidence: 82%

“…Mende et al. ()]. However, in a recent study, Truyen and Parrish () showed that 37% of the cats that were infected had been vaccinated at least once.…”

Section: Discussionmentioning

confidence: 99%

Genetic Analysis of Feline Panleukopenia Virus Full-length VP2 Gene in Domestic Cats Between 2006-2008 and 2012-2014, Portugal

Miranda

Vieira

Silva

et al. 2016

Transbound Emerg Dis

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“…FPV, a member of the species Carnivore protoparvovirus 1, which belongs to the genus Protoparvovirus within the family Parvoviridae, is a highly contagious pathogen in domestic and wild cats [1]. FPV is transmitted by the faecal-oral route and primarily infects young kittens aged 3-6 months [15,21], resulting in severe enteric and immunosuppressive diseases characterized by fever, depression, anorexia, vomiting, acute diarrhea, haemorrhagic enteritis and leukopenia [16]. At present, FPV is widely spread throughout the world, with a high mortality rate of 25% to 90% [18], 1 3 and represents a serious threat to the life and health of cats.…”

Section: Introductionmentioning

confidence: 99%

Development and application of a multiplex PCR method for the simultaneous detection and differentiation of feline panleukopenia virus, feline bocavirus, and feline astrovirus

Zhang

Niu

et al. 2019

Arch Virol

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A multiplex polymerase chain reaction (mPCR) assay was developed to detect and distinguish feline panleukopenia virus (FPV), feline bocavirus (FBoV) and feline astrovirus (FeAstV). Three pairs of primers were designed based on conserved regions in the genomic sequences of the three viruses and were used to specifically amplify targeted fragments of 237 bp from the VP2 gene of FPV, 465 bp from the NP1 gene of FBoV and 645 bp from the RdRp gene of FeAstV. The results showed that this mPCR assay was effective, because it could detect at least 2.25-4.04 × 10 4 copies of genomic DNA of the three viruses per μl, was highly specific, and had a good broad-spectrum ability to detect different genotypes of the targeted viruses. A total of 197 faecal samples that had been screened previously for FeAstV and FBoV were collected from domestic cats in northeast China and were tested for the three viruses using the newly developed mPCR assay. The total positive rate for these three viruses was 59.89% (118/197). From these samples, DNA from FPV, FBoV and FeAstV was detected in 73, 51 and 46 faecal samples, respectively. The mPCR testing results agreed with the routine PCR results with a coincidence rate of 100%. The results of this study show that this mPCR assay can simultaneously detect and differentiate FPV, FBoV and FeAstV and can be used as an easy, specific and efficient detection tool for clinical diagnosis and epidemiological investigation of these three viruses.Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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“…In einer Studie mit 350 teils geimpften und teils ungeimpften Katzen aus Süddeutschland lag die Antikörperprävalenz bei 71 %. Fast ein Drittel dieser Katzen war also nicht vor Panleukopenie geschützt (39). Bei 313 dieser Katzen war der Impfstatus bekannt.…”

Section: Antikörperprävalenz In Der Populationunclassified

“…Bis zu 30 % aller Katzen haben keine messbaren Antikörpertiter. Auch manche Katzen, die regelmäßig geimpft wurden, verfügen nicht über Antikörper (39). Die Impfung ist die wichtigste Maßnahme für den Schutz des Individuums und der Popula -tion.…”

Section: Introductionunclassified

Feline Panleukopenie – die wichtige Rolle von Antikörpern

Proksch¹,

Mende²,

Bergmann³

et al. 2018

Tierarztl Prax Ausg K

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ZusammenfassungDie feline Panleukopenie zählt zu den wichtigsten Infektionskrankheiten der Katze. Jede Katze sollte zuverlässig vor Panleukopenie geschützt sein. Eine erfolgreiche Grundimmunisierung ist für die Ausbildung einer belastbaren Immunität essenziell. Panleukopenie tritt nach wie vor häufig auf und betrifft vor allem Katzenwelpen. Maternale Antikörper spielen eine wichtige Rolle für den Schutz der Welpen. Aufgrund ihres langen Fortbestehens, teilweise bis zur 20. Lebenswoche, können maternale Antikörper jedoch mit der Impfung interferieren und den Aufbau einer belastbaren Immunität verhindern. So kannes trotz Impfung zu Erkrankungen kommen. Bei adulten Katzen mit chronischer Krankheit oder Immunsuppression kann die Immunantwort nach einer Impfung reduziert sein. Etwa 30% aller adulten Katzen haben keine Antikörper. Die Bestimmung des Antikörpertiters bei Welpen ermöglicht die Berechnung des optimalen Zeitpunkts für eine erfolgreiche Grundimmunisierung. Bei adulten Tieren bietet die Titerbestimmung eine Alternative, um unnötige Impfungen zu vermeiden und ein individuelles Impfschema zu ermitteln. Nur Katzen ohne Antikörper sollten geimpft werden. Zur Bestimmung des Antikörpertiters steht für die Praxis ein leicht durchführbarer Schnelltest zur Verfügung.

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Prevalence of antibodies against feline panleukopenia virus in client-owned cats in Southern Germany

Cited by 26 publications

References 23 publications

Genetic Analysis of Feline Panleukopenia Virus Full-length VP2 Gene in Domestic Cats Between 2006-2008 and 2012-2014, Portugal

Genetic Analysis of Feline Panleukopenia Virus Full-length VP2 Gene in Domestic Cats Between 2006-2008 and 2012-2014, Portugal

Development and application of a multiplex PCR method for the simultaneous detection and differentiation of feline panleukopenia virus, feline bocavirus, and feline astrovirus

Feline Panleukopenie – die wichtige Rolle von Antikörpern

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