Objectives: The aims of this study are to evaluate the hematological parameters, type and severity of spectrum of anemia in known anemic cases in adult age group. Methods: This study was carried out in the Department of Pathology, in a tertiary health care center on 1330 cases. The cases were from both indoor and outdoor patients admitted in various wards. The samples for test were collected in EDTA tube. The samples were run in hematology cell counter Sysmex XS-800i for hematology indices and other parameters. Results: The overall prevalence of anemia was 71.58%. Moderate degree of Anemia was the most common followed by mild degree. Anemia was present in 39.92% of men and in 60.08% of women. Microcytic hypochromic anemia is the most common type of anemia in adult, more in reproductive age group indicating iron deficiency as the main cause. It was followed by normocytic normochromic anemia both in men and women. Conclusion: Anemia is a widespread public health problem associated with an increased risk of morbidity and mortality, especially in pregnant women and young children. The prevalence of anemia increases with age and is associated with race, chronic diseases, nutritional deficiencies and other conditions such as infection. A diagnosis of anemia warrants adequate clinical attention, to find out the cause, type, severity and this forms the basis for treatment of anemia. RBC indices provide important guidelines for diagnosis, classification and monitoring the treatment of anemia .