Prevalence, Incidence And Characteristics Of Patients With Choroidal Neovascularization Secondary To Pathologic Myopia In A Representative Canadian Cohort

Zaour, N.; Luciani, L.; Petrella, RJ

doi:10.1016/j.jval.2014.03.1652

Cited by 2 publications

(2 citation statements)

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“…Specifically, fundus images were evaluated for the presence of the following: (1) MMD based on the international Meta Analyses of Pathologic Myopia (META-PM) classifications, where the presence of MMD was defined as META-PM MMD category 2 (diffuse atrophy) or worse (e.g., Figure 1A ), or the presence of plus signs (e.g., lacquer cracks, mCNV, or Fuchs spots; Figure 1B ) ( 6 ), (2) PPA (e.g., Figure 2A ), and (3) myopic tilted disc (e.g., Figure 2B ) defined as an optic disc with a ratio of minimal to maximal disc diameter of 0.75 or less and was assessed via the use of fundus photography ( 31 ). Given that Fuchs spot is considered a quiescent mCNV ( 32 ), and mCNV is one of the most commonly described features of PM ( 33 ), we included both active and quiescent forms in our prevalence of mCNV.…”

Section: Methodsmentioning

confidence: 99%

Multimodal Imaging-Based Phenotyping of a Singaporean Hospital-Based Cohort of High Myopia Patients

et al. 2022

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Purpose: To assess the effect of axial length (AL) on the prevalence of pathologic myopia (PM) and associated myopic features in a Singaporean hospital-based cohort of patient with high myopia (HM).Methods: In total, 923 HM eyes from 495 individuals were recruited from the Myopic and Pathologic Eyes in Singapore (MyoPES) cohort and underwent ocular biometry, fundus photography, fundus autofluorescence, and swept-source optical coherence tomography (SS-OCT). Images were analyzed for the presence of myopic macular degeneration (MMD), myopic choroidal neovascularization (mCNV), myopic traction maculopathy (MTM), peripapillary atrophy (PPA), myopic tilted disc, posterior staphyloma (PS), dome-shaped macula (DSM), vitremacular adhesions (VMA), and the epiretinal membrane (ERM). Eyes were stratified into quartiles based on ALs to determine cut-off values to perform comparisons between shorter-length and longer-length groups. A χ2-test was done to determine the difference in the prevalence of pathologies between groups.Results: Overall, mean AL was 29.2 ± 2.2 mm (range 25.0–36.7 mm). Myopic macular degeneration, PPA, myopic tilted disc, and ERM have AL threshold of ≥27.5 mm, whereas MTM has an AL threshold of ≥29.0 mm. We found that there was a significantly higher prevalence of MMD (88.2 vs. 49.4%; p < 0.001), PPA (98.1 vs. 80.1%; p < 0.001), myopic tilted disc (72.7 vs. 50.2%; p < 0.001), and ERM (81.4 vs. 17.3%; p = 0.003) in eyes with AL ≥ 27.5 mm vs. eyes without AL <27.5 mm. Prevalence of MTM (34.7 vs. 32.1%; p < 0.001), mCNV (17.4 vs. 12.1%; p = 0.03), PS (43.4 vs. 34.7%; p = 0.012), DSM (21.3 vs. 13.2%; p = 0.002), and VMA (5.9 vs. 2.6%; p = 0.014) in eyes with AL ≥ 29.0 mm compared with AL < 29.0 mm.Conclusion: Our study describes the overall prevalence of PM and related pathologies among patients with HM in our hospital-based cohort. Longer eyes even among HM eyes had a significantly higher prevalence of PM-associated pathologies studied. This supports the premise that eyes with longer AL, even among HM eyes may be at greater risk of vision-threatening changes and therefore merit regular follow-up.

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Section: Methodsmentioning

confidence: 99%

Multimodal Imaging-Based Phenotyping of a Singaporean Hospital-Based Cohort of High Myopia Patients

et al. 2022

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“…Willis et al [57] reported a prevalence of 0.017% for CNV in American people over 18y and 0.0079% in the over 65-year population. The majority of the studies presented the prevalence of CNV in patients with pathological myopia [58] ; for example, Wong et al [59] reported a prevalence of 5.2%-11.3% in different ethnic populations and Zaour et al [60] reported a prevalence of 6.2% in the Canadian population. The above values indicate that a higher percentage of the Iranian elderly population had CNV.…”

Section: Central Retinal Artery Occlusionmentioning

confidence: 99%

Prevalence of retinal pathologies in people over 60 years: the Tehran Geriatrics Eye Study

Mortazavi,

Jamali,

Hashemi

et al. 2024

Int J Ophthalmol

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AIM: To determine the prevalence of some retinal pathologies in people over 60y and their association with demographic and ocular factors. METHODS: A cross-sectional study was conducted in Tehran using multistage cluster sampling. After selecting subjects aged 60 and over, optometric, and ophthalmic examinations were done. For retinal examination, a 90 D lens was used and indirect ophthalmoscopy was performed after instilling tropicamide drops. Biometry was done using the IOL Master for all participants. RESULTS: Of 3791 people that were invited through cluster sampling, 3310 participated in the study (response rate=82%). The prevalence of retinal pigmented epithelium (RPE) change, drusen, geographic atrophy (GA), hypertensive retinopathy (HTR), nonproliferative diabetic retinopathy (NPDR), proliferative diabetic retinopathy (PDR), choroidal neovascularization (CNV), central retinal artery occlusion (CRAO), myopic retinopathy (MR), branch retinal vein occlusion (BRVO), and central retinal vein occlusion (CRVO) was 27.42%, 11.08%, 4.52%, 3.03%, 4.05%, 0.54%, 0.82%, 0.39%, 0.20%, 0.49%, and 0.19%, respectively. After removing the effect of age, the odds of NPDR were 1.68 times higher in women compared to men (P=0.014). After removing the effect of sex, the odds of drusen, RPE change, GA, CNV, BRVO, and CRVO increased with age. CONCLUSION: There is a higher prevalence of RPE change, drusen, GA, CNV and a lower prevalence of MR and CRAO in the elderly population of Tehran aged over 60y compared to global average values. Considering the correlation of most of the diseases with age and their effects on vision, attention should be paid to these diseases and the related screening programs to prevent vision impairment.

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Prevalence, Incidence And Characteristics Of Patients With Choroidal Neovascularization Secondary To Pathologic Myopia In A Representative Canadian Cohort

Cited by 2 publications

References 0 publications

Multimodal Imaging-Based Phenotyping of a Singaporean Hospital-Based Cohort of High Myopia Patients

Multimodal Imaging-Based Phenotyping of a Singaporean Hospital-Based Cohort of High Myopia Patients

Prevalence of retinal pathologies in people over 60 years: the Tehran Geriatrics Eye Study

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