Prévalence des marqueurs du virus de l'hépatite B chez des donneurs de sang vietnamiens

Hoàng, Bùi Hữu; Simonneau, M.; Xuan, Ping; Audat, F.; Guichoux, P.; Jaulmes, B

doi:10.1016/s0338-4535(85)80114-8

Cited by 5 publications

(2 citation statements)

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“…Because of its clinical consequences, such as liver cirrhosis and hepatocellular cancer, HBV is linked to significant morbidity and death [ 3 - 4 ]. HBV, a member of the Hepadnaviridae family, is composed of enveloped protein and small, double-stranded DNA [ 5 , 6 & 7 ]. The replicative cycle of the HBV genome involves an RNA intermediate that can integrate into the host genome and then survive in the infected cells, leading to HBV persistence [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

“…HBV, a member of the Hepadnaviridae family, is composed of enveloped protein and small, double-stranded DNA [ 5 , 6 & 7 ]. The replicative cycle of the HBV genome involves an RNA intermediate that can integrate into the host genome and then survive in the infected cells, leading to HBV persistence [ 7 ]. HBV infection can be accurately diagnosed using a combination of clinical, biochemical, histological, and serologic results [ 8 - 9 ].…”

Section: Introductionmentioning

confidence: 99%

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Persistence of hepatitis B surface antibody to hepatitis B vaccine among medical college students in Najran University, Saudi Arabia

Alshehri¹

2022

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Around 257 to 291 million people worldwide are infected with the hepatitis B virus (HBV). Immunization is one of the most effective ways to combat HBV infection. Saudi Arabia implemented a mandatory hepatitis B immunization program in 1989. This project investigated the levels of hepatitis B surface antibodies (anti-HBs) among medical students in the college of applied medical science at Najran University in December 2020. Students (n=82) were tested for anti-HBs levels using a chemiluminescent microparticle immunoassay (CMIA). Anti-HBs levels were the main outcome measures. Results showed that about 81.7% of participants had an insufficient amount of Anti-HBs levels (<10 IU/ L) compared to 18.3 % of participants who had protective levels of anti-HBs (≥10 IU/ L). However, 78.5% of the reactive group was at risk of losing immunity with a level between 12 and 42 IU/ L. Our study also showed an association between the age and the level of anti-HBs. Moreover, male students were at more risk than female students. Our results showed a strong relationship between Blood Groups and Anti-HBs antibody levels. The O+ (with 38.8%) and A+ (with 25.4%) blood groups showed the highest percentage amongst participants who had inadequate protection of anti-HBs (<10 IU/ L). Thus, data helps in our understanding and observations on anti-HBV immunity in individuals twenty years after being vaccinated as a child. According to the findings of our study, a large majority of students had a non-protective anti-HBs titer.

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