Prévalence de la trypanosomose bovine dans l’Etat de Gongola (Nord Nigeria)

Daniel, A. D.; Dadah, A.J.; Kalejaiye, J. O.; Dalhatu, A.

doi:10.19182/remvt.9411

Cited by 10 publications

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“…Five of these reported infection in cattle - bovine trypanosomiasis. 27,28, 29, 30,31 Two studies investigated trypanosomiasis infection in pigs – porcine trypanosomiasis. 32, 33 Three studies investigated infection in ruminants – sheep, goat, cattle, 34,35,36 while one study investigated in dogs – canine trypanosomiasis.…”

Section: Resultsmentioning

confidence: 99%

Prevalence of Human and Animal African Trypanosomiasis in Nigeria: A Scoping Review

Odebunmi,

Ibeachu,

Chukwudi

2024

Preprint

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Background: African trypanosomiasis continues to pose a substantial threat to both human and animal health in sub-Saharan Africa. This study examined the prevalence of African trypanosomiasis within human and animal populations in Nigeria, the trypanosome species involved, the spread of animal reservoirs, and the variability in diagnostic methodologies employed. Methodology/principal findings: A scoping review was performed, following the methodological framework outlined in PRISMA-ScR checklist. Eligible studies were explored for disease prevalence, causative parasites, reservoir hosts, and diagnostic techniques used. A total of 16 eligible studies published between 1993 and 2021 were retrieved. 13 studies reported the prevalence of African trypanosomiasis in animals, and 3 for humans. Varying prevalence rates were recorded depending on the host population and diagnostic methods employed. The overall prevalence of Animal African Trypanosomiasis (AAT) and Human African Trypanosomiasis (HAT) was 27.3% (4,404/16,117) and 3.6% (72/1,974) respectively. The highest incidence of HAT was detected using the Card Agglutination Test for Trypanosomiasis (CATT), whereas that of AAT was observed using PCR, followed by microscopy which was the most extensively employed technique in this study. The various diagnostic methods used in various studies showed a variety of sensitivities and specificities, affecting the accuracy of disease detection. Remarkably, domestic animals like cattle, pigs, and dogs were identified as potential reservoirs for the human-infective parasites (T. b. gambiense) in Nigeria. Conclusion: This study highlights the high prevalence rate and complex epidemiology of African trypanosomiasis in humans and animals in Nigeria. These findings underscore the importance of comprehensive measures involving both veterinary and human health sectors to combat African trypanosomiasis effectively in Nigeria. Only few studies have investigated the prevalence of HAT in Nigeria. Hence, adequately coordinated epidemiological surveys are imperative to ascertain the true epidemiological status of HAT in Nigeria and inform targeted intervention policies to achieve WHO’s NTD elimination targets in 2030.

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Section: Resultsmentioning

confidence: 99%

Prevalence of Human and Animal African Trypanosomiasis in Nigeria: A Scoping Review

Odebunmi,

Ibeachu,

Chukwudi

2024

Preprint

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“…Five of these reported infection in cattle -bovine trypanosomiasis. 23,24,25,26,27 Two studies investigated trypanosomiasis infection in pigsporcine trypanosomiasis. 28,29 Three studies investigated infection in ruminants -sheep, goat, cattle, 30,31,32 while one study investigated in dogs -canine trypanosomiasis.…”

Section: Description Of Eligible Studiesmentioning

confidence: 99%

Prevalence of Human and Animal African Trypanosomiasis in Nigeria: a Scoping Review

Odebunmi,

Ibeachu,

Chukwudi

2024

Preprint

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Background African trypanosomiasis affects both humans (HAT) and animals (AAT). HAT is an NTD targeted for elimination in 2030, and has not been officially reported by WHO from Nigeria in the last decade despite frequent reports of animal carriers. Conversely, the burden of AAT continues to increase. This study synthesized published evidence on the prevalence of African trypanosomiasis within human and animal populations in Nigeria, the trypanosome species involved, the spread of animal reservoirs, and the variability in diagnostic methodologies employed. Methodology/principal findings A scoping review was performed following the methodological framework outlined in PRISMA-ScR checklist. A total of 16 eligible studies published between 1993 and 2021 were reviewed. 13 studies reported the prevalence of AAT, and 3 for HAT. Varying prevalence rates were recorded depending on the diagnostic methods employed. The overall prevalence of HAT was 3.6%, and AAT 27.3%. The highest incidence of HAT was detected using the Card Agglutination Test for Trypanosomiasis (CATT), and AAT by PCR, followed by microscopy (the most used technique). Domestic animals like cattle, pigs, and dogs were identified as carriers of the human-infective trypanosomes (T. brucei gambiense). Conclusion This study highlights the high prevalence and complex epidemiology of African trypanosomiasis in humans and animals in Nigeria. Remarkably, published evidence indicate that HAT is highly prevalent in Nigeria despite not being reported by WHO. However, only few studies have investigated HAT in Nigeria, indicating limited disease surveillance. Unfortunately, diagnostics challenges and disease reporting protocols seem to limit HAT reporting to WHO. Therefore, adequately coordinated epidemiological surveys and targeted intervention policies are imperative to ascertain the true epidemiological status of HAT in Nigeria towards achieving WHO’s elimination targets in 2030. The presence of animal carriers of human-infective trypanosomes underscores the importance of a one-health approach to avoid breeding the next epidemic clone in Nigeria and combat African trypanosomiasis effectively.

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Animal African Trypanosomiasis in Nigeria: A long way from elimination/eradication

et al. 2017

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Prévalence de la trypanosomose bovine dans l’Etat de Gongola (Nord Nigeria)

Cited by 10 publications

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Prevalence of Human and Animal African Trypanosomiasis in Nigeria: A Scoping Review

Prevalence of Human and Animal African Trypanosomiasis in Nigeria: A Scoping Review

Prevalence of Human and Animal African Trypanosomiasis in Nigeria: a Scoping Review

Animal African Trypanosomiasis in Nigeria: A long way from elimination/eradication

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