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Subject. The prevalence of inflammatory periodontal diseases among elderly people, regardless of their gender, ranges from 69 to 98 % worldwide. Periodontitis is a chronic bacterial disease that proceeds with intoxication of the body, thereby causing serious health problems. It has been proven that periodontitis can cause myocardial infarction and habitual miscarriage. Local and systemic treatment of diseases of this pathology is primarily aimed at suppressing pathogenic bacteria. It is obvious that, in the conditions of total antibiotic resistance of microorganisms and a considerable list of contraindications and complications of the antibiotic therapy, the search for new ways to combat them becomes vital. The main thing is that antibiotics disrupt the biological balance of the biopsy of the body which the patient has to restore from several months to several years. Under these conditions, the use of bacteriophages is an extremely promising solution. Bacteriophages are natural antimicrobial highly sensitive medications. They consist of viruses that target a bacterial cell. In these circumstances, bacteriophages do not harm the microbiota of the oral cavity. A literature review on the use of bacteriophages in dentistry for the treatment of inflammatory diseases of periodontal tissues has been conducted by us. The mechanism of action of bacteriophages, the strengths and weaknesses of the use of phage therapy have also been considered. Goal ― to study the use of bacteriophages for the treatment of patients with inflammatory periodontal diseases. Methodology. The literature review of more than 40 scientific sources has been conducted. Conclusion. The use of bacteriophages is a promising issue. Their effectiveness has been confirmed in the treatment of infectious and inflammatory periodontal diseases and diseases of the oral mucosa. They demonstrate high efficiency to improve the hygiene of the oral cavity and reduce inflammation. Being highly targeted viral medications, they act upon a specific bacterium without affecting the natural microbiota of a person.
Subject. The prevalence of inflammatory periodontal diseases among elderly people, regardless of their gender, ranges from 69 to 98 % worldwide. Periodontitis is a chronic bacterial disease that proceeds with intoxication of the body, thereby causing serious health problems. It has been proven that periodontitis can cause myocardial infarction and habitual miscarriage. Local and systemic treatment of diseases of this pathology is primarily aimed at suppressing pathogenic bacteria. It is obvious that, in the conditions of total antibiotic resistance of microorganisms and a considerable list of contraindications and complications of the antibiotic therapy, the search for new ways to combat them becomes vital. The main thing is that antibiotics disrupt the biological balance of the biopsy of the body which the patient has to restore from several months to several years. Under these conditions, the use of bacteriophages is an extremely promising solution. Bacteriophages are natural antimicrobial highly sensitive medications. They consist of viruses that target a bacterial cell. In these circumstances, bacteriophages do not harm the microbiota of the oral cavity. A literature review on the use of bacteriophages in dentistry for the treatment of inflammatory diseases of periodontal tissues has been conducted by us. The mechanism of action of bacteriophages, the strengths and weaknesses of the use of phage therapy have also been considered. Goal ― to study the use of bacteriophages for the treatment of patients with inflammatory periodontal diseases. Methodology. The literature review of more than 40 scientific sources has been conducted. Conclusion. The use of bacteriophages is a promising issue. Their effectiveness has been confirmed in the treatment of infectious and inflammatory periodontal diseases and diseases of the oral mucosa. They demonstrate high efficiency to improve the hygiene of the oral cavity and reduce inflammation. Being highly targeted viral medications, they act upon a specific bacterium without affecting the natural microbiota of a person.
Subject. Currently, there is an increase in the prevalence of inflammatory and non-inflammatory diseases of the oral cavity, including those combined with various organs and systems. The article addresses the issue of the occurrence of dental diseases in patients with ongoing somatic pathologies, in particular with diseases of the cardiovascular system. Aim — study of the epidemiological characteristics of dental diseases in patients with diseases of the cardiovascular system. Methodology. Since 2015, an epidemiological study of 116 patients (87 in the main group and 29 in the comparison group) was conducted. The age range is 40-60 years, in the ratio of 57 % of women and 43 % of men. For each patient, an individually developed map was filled in which the indices of the solid and soft tissues of the oral cavity were noted, as well as microbial and cytological data. Also, each patient completes the Ohip-14 dental questionnaire. Results. Lesions of caries and its complications in all groups had a similar character. The prevalence of periodontal and oral mucosa diseases is 27.6 % higher in patients with coronary heart disease. Assessing the papillary-marginal-alveolar index (PMA), the level of differences in the groups was 15.5 %. Analysis of the periodontal index (PI) revealed intergroup differences of 16.6 %. The most significant differences were found in the processing of data on the need for treatment of periodontal disease (CPITN), which amounted to 40.7 %. The results of the Schiller—Pisarev test confirmed the propensity for inflammatory processes in the gums in patients with cardiovascular pathology. Evaluating the results of the Kulazhenko test, one can speak of a sharp decrease in the resistance of capillaries in periodontal tissues in cardiac patients, the level of differences was 56.6 %. Conclusion. Summing up the epidemiological characteristics of the prevalence of the considered dental indicators, one can speak of a greater propensity for periodontal disease and oral mucosa in cardiac patients, which is confirmed by periodontal indices and samples. Also, patients with cardiac diseases are 20.3 % worse than life quality indicators.
Object. Periodontitis, as a chronic disease, must be treated comprehensively, in stages, with subsequent preventive medical examination. Periodontal treatment being a time-consuming process, requires special cooperation from both the doctor and for the patient. The results of the treatment largely depend on the patient's involvement in the process of treatment. It depends on how efficiently and timely patients fulfill all the recommendations. The task of a dentist is to assess and increase the level of patients’ compliance to treatment. Objective. To study the effect of the use of doctor's appointment monitoring using the patient's self-monitoring diary on the effectiveness of periodontitis treatment. Materials and methods. The object of the study was 63 patients diagnosed with chronic generalized periodontitis aged 32 to 63 years, who were 44.6 ± 5.8 years old in average. The patients were divided into two groups (No. 1 and No. 2). Group No. 1, after diagnosis, a conversation was conducted about the importance of compliance with doctor’s recommendations and sequence of prescribed treatment. Also, every patient was given a step-by-step list of appointments with the patient's diary, which they were to fill out. Group No. 2 received only medical appointments and recommendations. Diagnosis and treatment were carried out in accordance with the protocol for the management of patients with periodontal diseases developed by Federal State Budgetary Educational Institution of Higher Education "Moscow State Medical and Dental University named after A. I. Evdokimov" of the Ministry of Health and Social Development of the Russian Federation, 2012. On the 7th day and after 1 month of the study, the effectiveness of the prescribed therapy was evaluated. Conclusions. The results of our study show that the appointment list and self-monitoring diary issued to patient are good ways to increase the patient's adherence to treatment, evaluation of medication intake, compliance with doctor's recommendations. This method undoubtedly increases the effectiveness of the prescribed treatment.
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