Prevalence and Progression Rate of Diabetic Retinopathy in Type 2 Diabetes Patients in Correlation with the Duration of Diabetes

Voigt, Margarete; Scheer, Sebastian; Lehmann, Thomas; Köhler, Benjamin; Kloos, C; Voigt, Ulrich; Meller, Daniel; Wolf, Günter; Müller, Ulrich; Müller, N

doi:10.1055/s-0043-120570

Cited by 90 publications

(62 citation statements)

References 31 publications

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“…Therefore, the prevalence of DR in patients would rise substantially when the patient's diabetic durations were over 10 years. 27 Some studies also found that the longer duration of diabetes, the higher chance of retinopathy appeared; with impact on the risk of DR. 17,24,28 The result of those studies were corresponding to our study. Therefore, well controlled earlier could prevent and delay the progression of DR in patients with diabetes.…”

Section: Discussionmentioning

confidence: 99%

The related risk factors of diabetic retinopathy in elderly patients with Type 2 diabetes mellitus: A cohort study

Chiu

Tsai

et al. 2020

Preprint

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KEYWORDS health behavior; chewing betel nut; dilated fundus examination 2 Abstract Background: Diabetic retinopathy (DR) caused by small vessel disease was the main cause of blindness in person with diabetes, and it mainly occurred in patients with Type 2 diabetes mellitus (T2DM). Taiwan was one of the Asian countries with the highest prevalence rate of DR, there were only few studies for the risk of DR in patients with T2DM in Taiwan. According to some studies have shown DR was a major cause of blindness on elderly both in developed and other developing countries. The purpose was to investigate the related risk factors of DR in elderly patients with T2DM. Methods: During July 2010 to December 2017, 4010 T2DM patients without DR were preselected for this study, but 792 patients completed the continuously follow-up evaluation. Patients were invited to have an outpatient visit at least every three months, and they were asked to fill out a brief questionnaire and collect their blood samples. Additionally, statistical methods used independent sample T-test, Chi-square tests and logistic regression in univariate analysis to analyze the relationships between onset DR and each related factor; and finally the optimal multivariate logistic regression model would be determined by stepwise model selection. Results: Of the 792 effective samples, 611 patients (77.1%) progressed to DR and 181 patients

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Section: Discussionmentioning

confidence: 99%

The related risk factors of diabetic retinopathy in elderly patients with Type 2 diabetes mellitus: A cohort study

Chiu

Tsai

et al. 2020

Preprint

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“…Many studies have reported a high prevalence (ranging from 11.9-43.1 %) of DR in adults with T2DM mainland China [20,21]. Some studies in Denmark and Germany showed that the prevalence of DR were 21.2 and 25.8 % in patients with T2DM [22,23]. The prevalence of DR patients was 7.2 and 13.1 % , in which young patients newly diagnosed with T2DM aged ≤ 21 years were enrolled in a large US managed-care network and a new diagnosis of T2DM in China, respectively [24,25].…”

Section: Discussionmentioning

confidence: 99%

“…Many studies have reported that increased duration of diabetes, poor blood glucose control, ineffective blood pressure control, and genetic factors are the major risk factors for DR [23,29,30]. In our study, FC-P and FBG were positively correlated with DR in the patients newly diagnosed with T2DM (P < 0.05), and the OR values of FC-P and FBG were 7.685 and 1.256, which indicate that FC-P levels were the highest risk factors for DR followed by FBG.…”

Section: Discussionmentioning

confidence: 99%

Serum CA 19–9 Level is Correlated to the Clinical Characteristics and Chronic Complications of Patients Newly Diagnosed with Type 2 Diabetes Mellitus

Cui

et al. 2019

Exp Clin Endocrinol Diabetes.

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Aim This study investigated the relation of serum carbohydrate antigen 199 (CA 19–9) levels to the clinical characteristics and chronic complications of patients newly diagnosed with type 2 diabetes mellitus (T2DM). Methods A total of 371 patients newly diagnosed with T2DM and 133 healthy people with consecutively matched age were compared. The 371 patients with T2DM were divided into four groups by quartiles based on their serum CA 19–9 levels, in which clinical characteristics and chronic complications, such as diabetic retinopathy (DR), diabetic nephropathy, and macrovascular complications were compared. Logistic regression analysis was used to evaluate the risk factors of DR. Results Among the 371 patients newly diagnosed with T2DM, 60 had elevated CA 19–9 levels (16.17%). The frequencies of elevated serum CA 19–9 were 24.39% (30 of 123) for females and 12.10% (30 of 248) for males, in which the values for females were higher than those for males (P<0.01).Differences were observed among the serum CA 19–9 levels, hemoglobin A1c (HbA1c), and DR (P<0.05). Logistic regression analysis showed that serum CA 19–9 levels, fasting blood glucose (FBG) and fasting C-peptide (FC-P) were risk factors for DR (P<0.05). Conclusions Serum CA 19–9 levels were correlated with HbA1c and DR in patients newly diagnosed with T2DM. The elevated serum CA 19–9 levels, high FC-P, and FBG levels were important risk factors for DR in patients newly diagnosed with T2DM.

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“…DR has a delayed onset and a slow, gradual progression over many years and can even regress when the disease is in an early mild form. [ 25 ]…”

Section: Discussionmentioning

confidence: 99%

The prevalence and risk factors of diabetic retinopathy in selected primary care centers during the 3-year screening intervals

Magliah

Bardisi

Attah

et al. 2018

J Family Med Prim Care

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Prevalence and Progression Rate of Diabetic Retinopathy in Type 2 Diabetes Patients in Correlation with the Duration of Diabetes

Cited by 90 publications

References 31 publications

The related risk factors of diabetic retinopathy in elderly patients with Type 2 diabetes mellitus: A cohort study

The related risk factors of diabetic retinopathy in elderly patients with Type 2 diabetes mellitus: A cohort study

Serum CA 19–9 Level is Correlated to the Clinical Characteristics and Chronic Complications of Patients Newly Diagnosed with Type 2 Diabetes Mellitus

The prevalence and risk factors of diabetic retinopathy in selected primary care centers during the 3-year screening intervals

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