Prevalence and factors associated with erectile dysfunction in a cohort of HIV-infected patients

Pérez, Isabel; Moreno, Tamara; Navarro, Ferrán Martínez; Santos, Jesús; Palacios, Rosario

doi:10.1177/0956462413482423

Cited by 26 publications

(49 citation statements)

References 26 publications

(42 reference statements)

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“…Although anxiety and guilt were not included in our evaluation, they have been previously assessed [ 35 ]. We also acknowledge that as the aim of this study was to relate metabolic and clinical variables with ED in patients with HIV, some other confounding variables were not included in our evaluation.…”

Section: Discussionmentioning

confidence: 99%

Erectile Dysfunction Among HIV Patients Undergoing Highly Active Antiretroviral Therapy: Dyslipidemia as a Main Risk Factor

et al. 2014

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ObjectiveTo assess the prevalence and risk factors of erectile dysfunction (ED) in HIV patients from the HIV clinic of a tertiary referral center in Mexico City.DesignPrevalence was obtained from cross-sectional studies, and the International Index of Erectile Function (IIEF), a standardized method, was used to assess ED.MethodsA cross-sectional study was performed in the HIV clinic. Participants completed the IIEF to allow ED assessment. Information on demographics, clinical and HIV-related variables was retrieved from their medical records.ResultsOne hundred and nine patients were included, with a mean age of 39.9 ± 8.8 years. ED was present in 65.1% of the individuals. Patients had been diagnosed with HIV for a mean of 92.7 ± 70.3 months and had undergone a mean 56.4 ± 45.5 months of HAART. The only variable associated with ED in the univariate analysis was dyslipidemia, and this association was also found in the multivariate analysis (P = 0.01).ConclusionsED is highly prevalent in HIV patients. Dyslipidemia should be considered as a risk factor for ED in HIV patients. Romero-Velez G, Lisker-Cervantes A, Villeda-Sandoval CI, Sotomayor de Zavaleta M, Olvera-Posada D, Sierra-Madero JG, Arreguin-Camacho LO, and Castillejos-Molina RA. Erectile dysfunction among HIV patients undergoing highly active antiretroviral therapy: Dyslipidemia as a main risk factor. Sex Med 2014;2:24–30.

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Section: Discussionmentioning

confidence: 99%

Erectile Dysfunction Among HIV Patients Undergoing Highly Active Antiretroviral Therapy: Dyslipidemia as a Main Risk Factor

et al. 2014

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“…The side effects experienced from taking necessary ART to prevent HIV progression is potentially a factor influencing the SRHR experiences of YPLWH ( 20 ). Evidence suggests that possible side effects of ART (and perhaps HIV infection itself) may negatively impact on sexual functioning – including decreased libido and erectile dysfunction – further affecting the SRHR of YPLWH ( 32 ).…”

Section: Treatment Adherence and Side Effectsmentioning

confidence: 99%

Interventions targeting sexual and reproductive health and rights outcomes of young people living with HIV: a comprehensive review of current interventions from sub-Saharan Africa

Pretorius¹,

Gibbs²,

Crankshaw³

et al. 2015

Global Health Action

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BackgroundA growing number of young people (ages 10–24) are living with HIV (YPLWH) in sub-Saharan Africa (SSA). These YPLWH have particular needs and challenges related to their sexual and reproductive health and rights (SRHR). Contextual factors including gender inequalities, violence, stigma, and discrimination and lack of tailored services undermine YPLWH's SRHR.ObjectiveUnderstand the scope and impact of interventions targeting YPLWH to improve SRH-related outcomes in SSA.DesignWe undertook a review to synthesise evaluated interventions (qualitative, quantitative, or mixed methods) aimed at improving the SRH outcomes of YPLWH in SSA with outcomes based on a World Health Organization framework of comprehensive SRHR approaches for women living with HIV. Using inclusion criteria, only six interventions were identified.ResultsInterventions sought to improve a range of direct and indirect SRH outcomes, including sexual behaviour, adherence, disclosure, and mental health. Four overarching issues emerged: 1) all interventions were structured according to cognitive behavioural therapy theories of behaviour change – while showing promise they do not tackle the wider gender, social, and economic contexts that shape YPLWH's SRH; 2) ‘significant others’ were included in two of the interventions, but further work needs to consider how to leverage parental/guardian support appropriately; 3) interventions only accessed young people who were already linked to care, participants were likely to have better SRH outcomes than those potentially more vulnerable YPLWH; and 4) none of the interventions explored the sexuality of young people.ConclusionsThere have been a limited number of evaluated interventions to strengthen SRH of YPLWH in SSA, and gaps exist in addressing the SRHR needs of YPLWH. Intervention approaches require greater scope and depth, including the need to address structural and contextual challenges.

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“…More recently, the 2011 US National Health and Wellness Survey showed that 24.6% of men aged 40 years and older had ED [10]. However, the reported prevalence of ED has appeared to be higher among HIV-infected men, ranging 25%–74% in various study populations [5–7, 11–14]. Using more stringent methodological criteria including adequate sample sizes and a validated questionnaire for ED assessment, a 2014 review found an ED prevalence of 50%–60% in HIV-infected men [15].…”

Section: Introductionmentioning

confidence: 99%

Erectile Dysfunction Medication Prescription and Condomless Intercourse in HIV-Infected Men Who have Sex with Men in the United States

et al. 2016

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Using nationally representative data, we assessed the prevalence of erectile dysfunction medication (EDM) prescription, and its association with insertive condomless anal intercourse (CAI) with an HIV-serodiscordant partner among sexually-active HIV-infected men who have sex with men (MSM) receiving medical care in the United States. Overall, 14% (95% CI 12–16) were prescribed EDM and 21% (95% CI 19–23) engaged in serodiscordant CAI. MSM who were prescribed EDM were more likely to engage in insertive CAI with a serodiscordant casual partner than those not prescribed EDM after adjusting for illicit drug use before or during sex (adjusted prevalence ratio=1.38; 95% CI 1.01–1.88). We found no association with main partners. Only 40% (95% CI 36–44) of MSM prescribed EDM received risk-reduction counseling from healthcare professionals. Risk-reduction counseling should be provided at least annually to all HIV-infected persons as recommended, especially at the time of EDM prescription.

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Prevalence and factors associated with erectile dysfunction in a cohort of HIV-infected patients

Cited by 26 publications

References 26 publications

Erectile Dysfunction Among HIV Patients Undergoing Highly Active Antiretroviral Therapy: Dyslipidemia as a Main Risk Factor

Erectile Dysfunction Among HIV Patients Undergoing Highly Active Antiretroviral Therapy: Dyslipidemia as a Main Risk Factor

Interventions targeting sexual and reproductive health and rights outcomes of young people living with HIV: a comprehensive review of current interventions from sub-Saharan Africa

Erectile Dysfunction Medication Prescription and Condomless Intercourse in HIV-Infected Men Who have Sex with Men in the United States

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