Prevalence and epidemiological characteristics of COVID-19 after one year of pandemic in Jakarta and neighbouring areas, Indonesia: A single center study

Setiadi, Wuryantari; Rozi, Ismail Ekoprayitno; Safari, Dodi; Daningrat, Wa Ode Dwi; Johar, Edison; Yohan, Benediktus; Yudhaputri, Frilasita A.; Lestari, Karina D; Oktavianthi, Sukma; Myint, Khin Saw Aye; Malik, Safarina G.; Soebandrio, Amin

doi:10.1371/journal.pone.0268241

Cited by 32 publications

(39 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Nevertheless, in the first wave of the pandemic, the mortality rate in this population was lower than that in other studies from a different tertiary hospital in Mexico [ 27 ]. In addition, other studies from Brazil and Indonesia have reported higher mortality rates, with 15% and 40%, respectively [ 28 , 29 ]. This difference might be due to the significantly higher number of patients in this study, which includes hospitalized and ambulatory patients from the four waves of the pandemic.…”

Section: Discussionmentioning

confidence: 98%

Clinical Characteristics of Coronavirus Disease (COVID-19) in Mexican Children and Adolescents

Flores-Alanis

Saldaña-Ahuactzi

Parra-Ortega

et al. 2022

Viruses

View full text Add to dashboard Cite

Background: We analyzed the demographic, clinical, and diagnostic data of children and adolescents in Mexico, from the first case of coronavirus disease (COVID-19) to 28 February 2022. Methods: Using the open databases of the Ministry of Health and a tertiary pediatric hospital, we obtained demographic and clinical data from the beginning of the COVID-19 pandemic until 28 February 2022. In addition, quantitative reverse-transcription polymerase chain reaction outputs were used to determine the viral load, and structural protein-based serology was performed to evaluate IgG antibody levels. Results: Of the total 437,832 children and adolescents with COVID-19, 1187 died. Of these patients, 1349 were admitted to the Hospital Infantil de Mexico Federico Gómez, and 11 died. Obesity, asthma, and immunosuppression were the main comorbidities, and fever, cough, and headache were the main symptoms. In this population, many patients have a low viral load and IgG antibody levels. Conclusion: During the first 2 years of the COVID-19 pandemic in Mexico, children and adolescents had low incidence and mortality. They are a heterogeneous population, but many patients had comorbidities such as obesity, asthma, and immunosuppression; symptoms such as fever, cough, and headache; and low viral load and IgG antibodies.

show abstract

Section: Discussionmentioning

confidence: 98%

Clinical Characteristics of Coronavirus Disease (COVID-19) in Mexican Children and Adolescents

Flores-Alanis

Saldaña-Ahuactzi

Parra-Ortega

et al. 2022

Viruses

View full text Add to dashboard Cite

show abstract

“…Viral RNA was extracted from plasma samples and used as a template for quantitative RT-PCR targeting a 200 bp region of the envelope (E1) gene [ 47 ]. Recently, the real-time RT-PCR technique was employed to detect and quantify SARS-CoV-2 in specimens collected from COVID-19 suspects or persons in contact tracing programs [ 48 , 63 , 64 ].…”

Section: Applicationsmentioning

confidence: 99%

“…Nasopharyngeal/oropharyngeal swabs have typically been used to confirm the clinical diagnosis. Notably, SARS-CoV-2 could also be detected in specimens from other sites such as bronchoalveolar lavage fluid, sputum, fiber bronchoscope brush biopsy, feces, and blood [ 64 , 70 ]. The real-time PCR method was applied to detect SARS-CoV-2 in more than 64,000 specimens collected from COVID-19 suspects or individuals in contact tracing programs in Jakarta and neighboring areas, Indonesia, within the first year of the COVID-19 pandemic [ 64 ].…”

Section: Detection and Quantification Of Sars-cov-2mentioning

confidence: 99%

“…Notably, SARS-CoV-2 could also be detected in specimens from other sites such as bronchoalveolar lavage fluid, sputum, fiber bronchoscope brush biopsy, feces, and blood [ 64 , 70 ]. The real-time PCR method was applied to detect SARS-CoV-2 in more than 64,000 specimens collected from COVID-19 suspects or individuals in contact tracing programs in Jakarta and neighboring areas, Indonesia, within the first year of the COVID-19 pandemic [ 64 ]. In order to assess environmental contamination with SARS-CoV-2 in a hospital setting, swab samples were collected from hospital surfaces such as intensive care unit (ICU) floors, medical floors, heating, ventilation, and air conditioning (HVAC) and then used for diagnosis of SARS-CoV-2 using RT-qPCR [ 71 ].…”

Section: Detection and Quantification Of Sars-cov-2mentioning

confidence: 99%

See 1 more Smart Citation

Real-Time Polymerase Chain Reaction: Current Techniques, Applications, and Role in COVID-19 Diagnosis

Artika

Dewi

Nainggolan

et al. 2022

Genes

View full text Add to dashboard Cite

Successful detection of the first SARS-CoV-2 cases using the real-time polymerase chain reaction (real-time PCR) method reflects the power and usefulness of this technique. Real-time PCR is a variation of the PCR assay to allow monitoring of the PCR progress in actual time. PCR itself is a molecular process used to enzymatically synthesize copies in multiple amounts of a selected DNA region for various purposes. Real-time PCR is currently one of the most powerful molecular approaches and is widely used in biological sciences and medicine because it is quantitative, accurate, sensitive, and rapid. Current applications of real-time PCR include gene expression analysis, mutation detection, detection and quantification of pathogens, detection of genetically modified organisms, detection of allergens, monitoring of microbial degradation, species identification, and determination of parasite fitness. The technique has been used as a gold standard for COVID-19 diagnosis. Modifications of the standard real-time PCR methods have also been developed for particular applications. This review aims to provide an overview of the current applications of the real-time PCR technique, including its role in detecting emerging viruses such as SARS-CoV-2.

show abstract

“…SARSCoV-2 can infect people of all ages. However, epidemiological studies indicate that older men (Setiadi et al, 2022), smokers, and patients with comorbid conditions such as diabetes mellitus, chronic obstructive lung disease, heart disease, and others have higher incidence and severity of the condition (Fu et al, 2020;Xiaofan Liu et al, 2020). Symptomatic or light instances make up 55% of cases in children and adolescent, moderate cases make up 40%, severe cases make up 5%, and very serious cases make up just 1% (CDC, 2020).…”

Section: Introductionmentioning

confidence: 99%

Diet Pattern and Psychological Conditions in Adolescents During Covid-19 Isolation

Sriwiyanti¹,

Hartati²

2022

CHIPROF

View full text Add to dashboard Cite

Social isolation has a negative impact on eating habits and mental health. especially in adolescents. Teenagers' daily lives have changed dramatically during the COVID-19 era due to the social restrictions that have been imposed, including the closure of schools, recreation centers and sports facilities. The purpose of this study was to assess the diet carried out during isolation with psychological adolescents. A total of 206 teenagers took the online survey. Participants showed negative psychological, and healthy diet at moderate limits. Hierarchical regression analysis shows that a healthy diet has a positive psychological effect. The results of the study found that adolescent psychology in this study was below the threshold recommended by the World Health Organization as an indication of possible depressive symptoms, measures to reduce wrong dietary behavior in adolescents a priority for the community and policy makers.

show abstract

Prevalence and epidemiological characteristics of COVID-19 after one year of pandemic in Jakarta and neighbouring areas, Indonesia: A single center study

Cited by 32 publications

References 17 publications

Clinical Characteristics of Coronavirus Disease (COVID-19) in Mexican Children and Adolescents

Clinical Characteristics of Coronavirus Disease (COVID-19) in Mexican Children and Adolescents

Real-Time Polymerase Chain Reaction: Current Techniques, Applications, and Role in COVID-19 Diagnosis

Diet Pattern and Psychological Conditions in Adolescents During Covid-19 Isolation

Contact Info

Product

Resources

About