Prevalence and Determinants of COVID-19 Vaccine Acceptance Among Healthcare Workers: A Systematic Review

Abstract

COVID-19 is a major public health problem that has been seriously affecting the global community. Healthcare workers (HCWs) are at high risk of infection due to being directly involved in diagnosing and taking care of patients. Due to this, they were prioritized to receive the initial supply of vaccines. However, vaccine hesitancy has been identified as a major global public health threat. Therefore, this review aimed to synthesize pieces of evidence on the prevalence of COVID-19 vaccine acceptance and determinate factors among HCWs. A systematic search of published articles was identified using PubMed, Science Direct, Web of Science, and Google Scholar for relevant studies of vaccine acceptance and determinant factors among HCWs. Published articles were identified using abstracts and titles of the articles, and articles were assessed for eligibility criteria. The review process was conducted according to the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). An electronic database search identified 365 articles, from which 33 full-text articles were included in the systematic review. In this review, the highest rate of vaccine acceptance was reported at 95% and the lowest rate of vaccine acceptance was found at 21%. Factors such as sex (male), age, profession (medical doctors), and previous influenza vaccination were the main positive predictors for COVID-19 vaccine acceptance among HCWs. Concerns about vaccine safety, efficacy, and effectiveness were the main barriers and drivers for vaccine hesitancy. Therefore, to improve the COVID-19 vaccine acceptance among HCWs, governments, public health authorities, and private healthcare systems should work together to provide continuous professional development and training on the safety and effectiveness of the COVID-19 vaccine.

COVID-19 Vaccine Hesitancy among Italian Healthcare Workers: Latent Profiles and Their Relationships to Predictors and Outcome

“…In a recent metanalysis, Wang and colleagues found that the global pooled acceptance rate of COVID-19 vaccination was 67.8% (95% CI: 67.1–68.6) among the general population, and 67.5% (95% CI: 64.4–70.6) among HCWs [ 7 ]. For example, recently, a systematic review reported that vaccine acceptance amongst HCWs correlated with their willingness to recommend the COVID-19 vaccination to their patients [ 8 ]. In this sense, it is necessary to investigate HCWs’ COVID-19 vaccine hesitancy to better understand the barriers, especially considering the last WHO’s global COVID-19 vaccination strategy [ 9 ].…”

COVID-19 Vaccine Uptake among Healthcare Workers: A Systematic Review and Meta-Analysis

“…Several systematic reviews and meta-analyses investigated intention of HCWs to accept a COVID-19 vaccine [ 21 , 22 , 23 , 24 , 25 ]. Evidence shows that the main predictors for COVID-19 vaccine acceptance among HCWs are male gender, older age, and previous influenza vaccination.…”

Uncommon Side Effects of COVID-19 Vaccination in the Pediatric Population

“…Hesitancy against vaccines is common in public and among healthcare workers, with post-vaccination side effects being the key barrier [ 57 ]. Open discussion about the possible side effects and reinforcing the individual, family, and community benefits are key to promoting acceptance [ 58 ]. Addressing the unique barriers to vaccine acceptance based on community dynamics, sociocultural factors, and vaccine criticism while providing well-informed messaging is vital [ 59 , 60 ].…”