Prevalence and Determinants of Angle Closure in Central Sri Lanka: The Kandy Eye Study

Casson, Robert J.; Baker, Michelle; Edussuriya, Kapila; Senaratne, Tissa; Selva, Dinesh; Sennanayake, Saman

doi:10.1016/j.ophtha.2009.03.005

Cited by 57 publications

(52 citation statements)

References 21 publications

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“…Previous studies have found that women are more likely to develop angle-closure glaucoma. (21,29,30) CPACG eyes also have significantly shorter axial lengths, shallower anterior chamber depths and less myopia than POAG eyes.…”

Section: Discussionmentioning

confidence: 98%

A prospective comparison of chronic primary angle-closure glaucoma versus primary open-angle glaucoma in Singapore

Ngo¹,

Aquino²,

Shabana³

et al. 2013

smedj

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the optic disc, visual field and ocular characteristics (such as intraocular pressure [IOP] at presentation, best-corrected visual acuity, sphere equivalent, mean keratometry, axial length, lens thickness, corneal thickness and lens opacity) of a consecutive cohort of Asian patients with CPACG, and to compare them with a similarly enrolled sample of patients with POAG. METHODSThis was a prospective comparative study of new patients with POAG or CPACG, who presented to the National University Health System, a tertiary eye care centre in Singapore, from January 2002 to June 2009. These were newly diagnosed patients, with no previous treatment or laser therapy done. The patients, who presented with unrelated eye conditions, were found to have clinical signs suggestive of glaucoma. They were referred from general ophthalmology clinics and community screening programmes for diabetes mellitus and glaucoma, as they were found to have suspicious discs or raised IOP. Ethics approval was obtained from the institutional review board and the study was conducted in accordance with the Declaration of Helsinki.Written informed consent was obtained from all study participants prior to enrolment in the study. RESULTS 98 patients were enrolled (POAG n = 48; CPACG n = 50). CPACG patients were significantly older (66.5 ± 9.2 years vs. 64.1 ± 13.5 years; p = 0.027) and mostly female (p = 0.004). CPACG eyes had significantly higher intraocular pressure (26.9 ± 6.9 mmHg vs. 24.5 ± 3.3 mmHg; p = 0.03), shorter axial length (22.89 ± 0.97 mm vs. 24.26 ± 1.79 mm; p < 0.001) and shallower anterior chamber depth (2.60 ± 0.25 mm vs. 3.16 ± 0.48 mm; p < 0.001). HVF mean deviation or pattern standard deviation (PSD) did not differ significantly between POAG and CPACG eyes, but the latter had a lower PSD for a given mean deviation. HRT parameters between the two groups were not significantly different. CONCLUSIONIn this study, CPACG eyes had significantly higher presenting intraocular pressure than POAG eyes, but there were no significant differences in optic disc topography. A majority of the patients in both groups had moderate field defects at the time of presentation, followed by severe and then mild defects. The field loss in CPACG eyes was more diffuse than that in POAG eyes.

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Section: Discussionmentioning

confidence: 98%

A prospective comparison of chronic primary angle-closure glaucoma versus primary open-angle glaucoma in Singapore

Ngo¹,

Aquino²,

Shabana³

et al. 2013

smedj

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“…17,[19][20][21] The prevalence of angle-closure glaucoma in the KES has been reported elsewhere. 22 The prevalence of POAG increased exponentially with age ( Figure 1). This is a well-established finding across all epidemiological studies on glaucoma.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of and Risk Factors for Primary Open-Angle Glaucoma in Central Sri Lanka: the Kandy Eye Study

Sia

Edussuriya

Sennanayake

et al. 2010

Ophthalmic Epidemiology

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“…The central anterior chamber depth (ACD) is measured as a representative value of the anterior ocular segment and is considered to be a useful screening parameter for angle closure [1][2][3]. However, the central ACD has some limitations in identifying eyes with angleclosure, such as difficulty in differentiating patients with plateau iris syndrome from those without angle-closure [3,4].…”

Section: Introductionmentioning

confidence: 99%

Comparison of the anterior ocular segment measurements using swept-source optical coherent tomography and a scanning peripheral anterior chamber depth analyzer

et al. 2011

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Prevalence and Determinants of Angle Closure in Central Sri Lanka: The Kandy Eye Study

Cited by 57 publications

References 21 publications

A prospective comparison of chronic primary angle-closure glaucoma versus primary open-angle glaucoma in Singapore

A prospective comparison of chronic primary angle-closure glaucoma versus primary open-angle glaucoma in Singapore

Prevalence of and Risk Factors for Primary Open-Angle Glaucoma in Central Sri Lanka: the Kandy Eye Study

Comparison of the anterior ocular segment measurements using swept-source optical coherent tomography and a scanning peripheral anterior chamber depth analyzer

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